Body Fluids and Their Neutrality

PEDIATRICS ◽  
1964 ◽  
Vol 33 (4) ◽  
pp. 632-632
Author(s):  
MALCOLM A. HOLLIDAY

It is not often that a medical textbook contains the qualities of a fresh style in writing, lucidity, and due respect for scientific accuracy. Dr. Christensen achieves this in the book Diagnostic Biochemistry and now in the shorter paper-bound version. Each chapter deals with a physico-chemical aspect of body fluids and relates it to clinical chemistry and to clinical disease. At the end of each chapter one finds a series of questions, not very easy ones at that, to provoke the intellectually curious into thought and library research.

2001 ◽  
Vol 47 (12) ◽  
pp. 2166-2178 ◽  
Author(s):  
Noel G Coley

Abstract I review here key research in the early years of the field of blood chemistry. The review includes successes and limitations of animal chemistry in the critical period of the eighteenth and nineteenth centuries. Eighteenth century medical theories emphasized the primacy of body solids. Body fluids were governed by the tenets of humoral pathology. After Boerhaave sparked interest in the chemistry of the body fluids, a new humoralism developed. With the rise of animal chemistry in the eighteenth century, two complementary ideas came into play. The concept of vital force was introduced in 1774, and the chemical composition of animal matters, including the blood, began to be investigated. In the early nineteenth century, the development of new methods of analysis encouraged such chemical studies. Prominent chemists led the field, and physicians also became involved. Physiologists were often opposed to the chemical tradition, but François Magendie recognized the importance of chemistry in physiology. Liebig linked the formation and functions of the blood to general metabolism and so extended the scope of animal chemistry from 1842. About the same time, microscopic studies led to discoveries of the globular structure of the blood, and Magendie’s famous pupil, Claude Bernard, began the animal chemistry studies that led him to new discoveries in hematology. This review addresses discoveries, controversies, and errors that relate to the foundations of clinical chemistry and hematology and describes contributions of instrumental investigators.


2013 ◽  
Vol 29 ◽  
pp. 89-95
Author(s):  
Sharda Yadav ◽  
Sanjaya KC

Clinical chemistry is emerging area in the field of clinical medicine which deals with the estimation of different analytes from body fluids. Different drugs interfere with the estimation of these analyte. The interference can be either physiological or analytical. Out of many analytes the most commonly estimated analyte are glucose, urea, creatinine, sodium and potassium. Small changes in these analytes also might give misleading information to the clinician. Though the clinicians will be aware of the major side effects of the drug, minor physiological effect might be overlooked also the analytical procedure and the effect of drug in different analytes. Hence, it is necessary for laboratory to inform clinicians regarding the possible effects of drugs on analytes.DOI: http://dx.doi.org/10.3126/jncs.v29i0.9257Journal of Nepal Chemical Society Vol. 29, 2012 Page:  89-95 Uploaded date: 12/5/2013 


1961 ◽  
Vol 7 (3) ◽  
pp. 297-299
Author(s):  
Helmut Richter

Abstract A simple, effective system is presented by which pipets can be completely and thoroughly cleaned of lipids, blood, and other body fluids which tend to leave a coating—a problem common to hospital and other laboratories.


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