scholarly journals Early Blood Chemistry in Britain and France

2001 ◽  
Vol 47 (12) ◽  
pp. 2166-2178 ◽  
Author(s):  
Noel G Coley
Keyword(s):  
Eighteenth Century ◽  
Clinical Chemistry ◽  
Blood Chemistry ◽  
Body Fluids ◽  
The Body ◽  
Early Years ◽  
Globular Structure ◽  
Humoral Pathology ◽  
Claude Bernard ◽  
Microscopic Studies

Abstract I review here key research in the early years of the field of blood chemistry. The review includes successes and limitations of animal chemistry in the critical period of the eighteenth and nineteenth centuries. Eighteenth century medical theories emphasized the primacy of body solids. Body fluids were governed by the tenets of humoral pathology. After Boerhaave sparked interest in the chemistry of the body fluids, a new humoralism developed. With the rise of animal chemistry in the eighteenth century, two complementary ideas came into play. The concept of vital force was introduced in 1774, and the chemical composition of animal matters, including the blood, began to be investigated. In the early nineteenth century, the development of new methods of analysis encouraged such chemical studies. Prominent chemists led the field, and physicians also became involved. Physiologists were often opposed to the chemical tradition, but François Magendie recognized the importance of chemistry in physiology. Liebig linked the formation and functions of the blood to general metabolism and so extended the scope of animal chemistry from 1842. About the same time, microscopic studies led to discoveries of the globular structure of the blood, and Magendie’s famous pupil, Claude Bernard, began the animal chemistry studies that led him to new discoveries in hematology. This review addresses discoveries, controversies, and errors that relate to the foundations of clinical chemistry and hematology and describes contributions of instrumental investigators.

Chemistry of the body fluids of the coelacanth, Latimeria chalumnae

1980 ◽  
Vol 208 (1172) ◽  
pp. 329-347 ◽  
Keyword(s):  
Sea Water ◽  
Water Environment ◽  
Blood Chemistry ◽  
Body Fluids ◽  
The Body ◽  
Coelomic Fluid ◽  
Rectal Gland ◽  
Internal Fertilization ◽  
Latimeria Chalumnae ◽  
Trimethylamine Oxide

The coelacanth, Latimeria chalumnae , possesses a blood chemistry that is nearly identical to that of the elasmobranch fishes and contrasts with that of the bony fishes and tetrapods. Especially notable is the retention of high concentrations of urea (377 mM) and of trimethylamine oxide (122 mM), which aid in raising the blood osmolarity (942 mosm/I) to close to that of the sea water environment. These features also characterize other coelacanth body fluids, such as the notochordal fluid, aqueous and vitreous humours, ventricular fluid, coelomic fluid and bile. The tissues of Latimeria , such as muscle, are also characterized by high urea concentrations. The osmotic balance between extracellular fluids and tissues seems to be achieved by the presence of very high tissue levels of trimethylamine oxide ( ca . 300 mmol/(kg H 2 O)), which counteract the low ion concentrations found in tissue. Renal function in Latimeria seems to involve the selective elimination of certain divalent ions (magnesium, phosphate and sulphate) and of organic substances (glucuronate, creatine and some amino acids). Unlike other ureosmotic fishes, the coelacanth does not possess the renal capacity to reabsorb urea. Evidence suggests that the rectal gland, structurally much like those of chondrichthyians, functions to excrete excess sodium chloride. Since the blood osmolarity of Latimeria is some­what lower than that of sea water (942 cf. 1026 mosm/l), it is in negative water balance. Some evidence suggests that this is overcome by drinking sea water in a manner similar to that of the teleosts. The problem of whether ureosmotic regulation is homologous in Latimeria and the chondrichthyians is moot, although we favour the possibility that it was independently acquired for the following reasons. (1) Renal urea reabsorbtion is absent in Latimeria although it is crucial to ureosmotic regulation in the chondrichthyians. (2) Internal fertilization and development are necessary concomitants of ureosmotic regulation in fishes and internal fertilization in the two groups is achieved by non-homologous mechanisms. (3) Ureosmotic regulation has been evolved independently in a third vertebrate group, the euryhaline amphibian Rana cancrivora .

IMPLEMENTATION OF FATWA ULAMA COUNCIL ACEH CONCERNING MAINTAINING FARDHU KIFAYAH FOR THE MUSLIM’S CORPSE INFECTED BY COVID 19 IN BANDA ACEH

2020 ◽  
Author(s):  
Andri Nirwana
Keyword(s):  
Health Workers ◽  
Descriptive Analysis ◽  
Body Fluids ◽  
The Body ◽  
Analysis Approach ◽  
Data Sets ◽  
Infected People ◽  
The Public ◽  
The People ◽  
Banda Aceh

Abstract: The phenomenon of the people who forcibly took covid's corpse 19 from the hospital to be taken care of by Fardhu Kifayah by his family and the community, became a conclusion that there was community doubt about the management of Tajhiz Mayat conducted by the hospital. Coupled with the circulation of the video of the Ruku movement 'in the corpse prayer conducted by unscrupulous parties at the Hospital, became added doubts from the public against the hospital. To solve this problem, this research uses a Descriptive Analysis approach, namely by formulating a question, namely How to arrange Covid 19's body in Banda Aceh and this question will be answered with several theories and data sets from the field. So it was concluded in a conclusion that answered the formulation of the problems mentioned. Theoretically the spread of covid 19 is very fast, the size of the virus is only 0.1 micrometer and is in body fluids, especially nasopharyngeal fluid and oropharyngeal fluids of infected people, fluids in the body of covid 19 bodies can get out through every gap of the body such as mouth, nose, eye and rectum, because it requires special techniques in its management. Fardhu kifayah to covid 19 bodies should be carried out by trained Ustad and trained health workers, so that the spread stopped. The results of this study concluded that the management of the Moslem bodies died at Zainal Abidin Hospital in Banda Aceh was in accordance with the Fatwa of the Aceh Ulama Council (MPU) and the bodies were handled by trained Ustad and health workers.

Locating the Historical and Contemporary Context of Women’s Imprisonment

2018 ◽  
Author(s):  
Anastasia Chamberlen
Keyword(s):  
Eighteenth Century ◽  
The Body ◽  
Historical Account ◽  
Women’S Experiences ◽  
Contemporary Research ◽  
Women's Experiences ◽  
Women's Prisons ◽  
Women's Imprisonment ◽  
Contemporary Context

This chapter sketches the broader context of the study presented in this book. It starts with a historical account of imprisonment, focusing particularly on women’s imprisonment, and attempts to trace the centrality of prisoner bodies in the delivery of punishment via the prison since the eighteenth century. Through this brief historiography, it examines how the body has been the object and subject of punishment and, since the start, has been part and parcel of the delivery of imprisonment. More specifically, the chapter argues that, since its establishment, women’s imprisonment has been gendered and embodied. The second half of the chapter looks at more contemporary research on women’s experiences in prison, and unpacks the punishment–body relation by connecting the study’s objectives to extant research on women’s prisons.

scholarly journals Analysis of the ex-vivo transformation of semen, saliva and urine as they dry out using ATR-FTIR spectroscopy and chemometric approach

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tanurup Das ◽  
Abhimanyu Harshey ◽  
Ankit Srivastava ◽  
Kriti Nigam ◽  
Vijay Kumar Yadav ◽  
...  
Keyword(s):  
Phase I ◽  
Phase Ii ◽  
Ex Vivo ◽  
Body Fluids ◽  
Biochemical Changes ◽  
Partial Least Square ◽  
The Body ◽  
Slow Phase ◽  
Time Since Deposition ◽  
Dry Out

AbstractThe ex-vivo biochemical changes of different body fluids also referred as aging of fluids are potential marker for the estimation of Time since deposition. Infrared spectroscopy has great potential to reveal the biochemical changes in these fluids as previously reported by several researchers. The present study is focused to analyze the spectral changes in the ATR-FTIR spectra of three body fluids, commonly encountered in violent crimes i.e., semen, saliva, and urine as they dry out. The whole analytical timeline is divided into relatively slow phase I due to the major contribution of water and faster Phase II due to significant evaporation of water. Two spectral regions i.e., 3200–3400 cm−1 and 1600–1000 cm−1 are the major contributors to the spectra of these fluids. Several peaks in the spectral region between 1600 and 1000 cm−1 showed highly significant regression equation with a higher coefficient of determination values in Phase II in contrary to the slow passing Phase I. Principal component and Partial Least Square Regression analysis are the two chemometric tool used to estimate the time since deposition of the aforesaid fluids as they dry out. Additionally, this study potentially estimates the time since deposition of an offense from the aging of the body fluids at the early stages after its occurrence as well as works as the precursor for further studies on an extended timeframe.

scholarly journals Epithelial Protein Lost in Neoplasm, EPLIN, the Cellular and Molecular Prospects in Cancers

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1038
Author(s):  
Jianyuan Zeng ◽  
Wen G. Jiang ◽  
Andrew J. Sanders
Keyword(s):  
The Body ◽  
Early Years ◽  
Actin Binding ◽  
Cell Cycle Gene ◽  
Lim Domain ◽  
The Past ◽  
Concise Review ◽  
Cancerous Cell ◽  
Cytoskeletal Dynamics ◽  
In Cells

Epithelial Protein Lost In Neoplasm (EPLIN), also known as LIMA1 (LIM Domain And Actin Binding 1), was first discovered as a protein differentially expressed in normal and cancerous cell lines. It is now known to be key to the progression and metastasis of certain solid tumours. Despite a slow pace in understanding the biological role in cells and body systems, as well as its clinical implications in the early years since its discovery, recent years have witnessed a rapid progress in understanding the mechanisms of this protein in cells, diseases and indeed the body. EPLIN has drawn more attention over the past few years with its roles expanding from cell migration and cytoskeletal dynamics, to cell cycle, gene regulation, angiogenesis/lymphangiogenesis and lipid metabolism. This concise review summarises and discusses the recent progress in understanding EPLIN in biological processes and its implications in cancer.

scholarly journals Exploratory Factor Analysis of Rainbow Trout Serum Chemistry Variables

2021 ◽  
Vol 18 (4) ◽  
pp. 1537
Author(s):  
Maurizio Manera
Keyword(s):  
Factor Analysis ◽  
Rainbow Trout ◽  
Exploratory Factor Analysis ◽  
Clinical Chemistry ◽  
Blood Chemistry ◽  
Hepatosomatic Index ◽  
Physiological Status ◽  
Serum Chemistry ◽  
Clinical Tool ◽  
Correlated Variables

Clinical chemistry offers a valuable, affordable, moderately invasive, and nondisruptive way to assess animal physiological status and wellness within defined ranges and is widely used as a diagnostic clinical tool. Because of physiological differences between mammals, clinical correlates of blood chemistry variables are not known in detail in fish, in which tissue/organ function tests are inferred from mammal-derived clinical chemistry data. The aim of the present study was to apply exploratory factor analysis on a serum chemistry dataset from clinically healthy, reared rainbow trout Oncorhynchusmykiss (Walbaum, 1792) to select the most correlated variables and to test for possible underlying factors explaining the observed correlations as possible physiological status estimates in trout. The obtained factors were tested for correlation with hepatosomatic and splenosomatic indexes. Thirteen highly correlated variables were selected out of 18 original serum chemistry variables, and three underlying factors (Factors 1, 2, and 3) were identified that explained the observed correlations among variables. Moreover, Factor 1 correlated negatively with the hepatosomatic index and Factors 2 and 3 negatively with the splenosomatic index. The obtained factors were tentatively associated with: protein (liver) metabolism (Factor 1), cell turnover (Factor 2), and lipid (muscle) metabolism (Factor 3).

Maiden Voyage

Nuncius ◽  
2011 ◽  
Vol 26 (1) ◽  
pp. 21-49
Author(s):  
Dario De Santis
Keyword(s):  
Eighteenth Century ◽  
Human Body ◽  
Scientific Community ◽  
Microscopic Investigation ◽  
The Body ◽  
Natural Phenomena ◽  
Scientific Debate

AbstractThe scientific debate which developed during the eighteenth century, proposed and diffused new theories on the generation not only within the scientific community. Microscopic investigation and various experimental campaigns fostered daring models attempting to unveil the natural phenomena from which life originates. Besides the famous scientific and philosophical works that marked the age, in the second part of the century two pamphlets appeared that well represent the importance of the querelle about embryological systems defining the concept of generation as a voyage within the human body. Lucina sine concubitu and Juno abortans, respectively published in England and in Germany between 1750 and 1760, narrate the odd and imaginary adventures of two doctors who are trying to interrupt and modify the embryos' journey towards the body of the mother.

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