In Reply: Radionuclide Brain Scans in Convulsive Disorders?

PEDIATRICS ◽  
1972 ◽  
Vol 49 (5) ◽  
pp. 788-788
Author(s):  
Melvin Tefft

I have noted the review of the experience of the Children's Hospital Medical Center, by Page, et al., in which gliomas related to epilepsy had an incidence of only 0.3%. However, as noted in the original article as published in Pediatrics of November 1971, lesions other than low grade gliomas may cause epileptiform seizures, including various benign lesions, and thus the overall incidence of abnormality might well be raised above the 0.3% level for malignant lesions.

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii386-iii386
Author(s):  
Nune Karapetyan ◽  
Samvel Danielyan ◽  
Gevorg Tamamyan ◽  
Armen Tananyan ◽  
Liana Safaryan ◽  
...  

Abstract BACKGROUND Central nervous system (CNS) tumors are the second most common malignant neoplasms among children worldwide. The current paper aims to analyze the situation in pediatric neuro-oncology in Armenia from the neurosurgical perspective. METHODS We have collected data of pediatric patients with CNS tumors treated in the Neurosurgery department of “Surb Astvasamayr” Medical Center from 01.01.2010 till 01.12.2019. Incidence by gender, age at diagnosis, and histopathology results were calculated. Survival rates were calculated based on the follow-up results performed until 30.12.2019. RESULTS Hospital-based data showed that during the previous 10 years 47 patients with CNS tumors received neurosurgical treatment in the unit, among them 66% were females. 38.3%, 31.9% and 29.8% of diagnosed patients were aged 0–4, 5–9, and 10–18 respectively. In 41 cases, the disease was not disseminated at diagnosis. The most common observed malignancies were low-grade gliomas (21.3%) and embryonal tumors (19.1%), followed by high-grade gliomas (14.9%) and ependymal tumors (8.5%). Follow-up information only for 33 patients is available. From them, 14 are dead and 19 alive. Survival rates in most common groups were 62.5%, 80%, 50%, and 50% respectively. The median follow-up time was 18 months (range 1–113 months). CONCLUSION Similar to the data reported in the literature, low-grade gliomas, and embryonal tumors are the most frequent pediatric CNS tumors in Armenia. On the other hand, the pediatric CNS tumor survival rates are lower compared to those reported in developed countries.


PEDIATRICS ◽  
1973 ◽  
Vol 52 (6) ◽  
pp. 818-822
Author(s):  
Richard Galdston ◽  
Alan D. Perlmutter

This report comprises concurrent studies of the urologic and psychiatric manifestations of intrapsychic conflict among a group of children who had been admitted to the surgical wards of The Children's Hospital Medical Center, Boston, between 1965 to 1970 for complaints of disordered urination. Experience with these children indicates that anxiety can alter the frequency and disturb the adequacy of voiding to a degree sufficient to dispose the child to urinary tract infection. This effect of anxiety can occur both in the presence or absence of a demonstrable anatomic lesion. It suggests that an assessment of the degree and nature of the child's anxiety should be an integral part of the pediatric urologic examination.


PEDIATRICS ◽  
1974 ◽  
Vol 54 (5) ◽  
pp. 658-658
Author(s):  
Frederick H. Lovejoy

Rumack and Temple in their thoughtful analysis of Lomotil poisoning1 note that narcotic antagonists should be used "as soon as adequate indications exist." From our experience with Lomotil toxicity in the last three years at Children's Hospital Medical Center and with other drugs producing narcotic like effects,2.3 we would like briefly to comment on the indications for the use of the narcotic antagonist, naloxone (Narcan) hydrochloride. Four prominent signs of naloxone efficacy exist: (1) dilatation of constricted pupils; (2) increase in depth and rate of respiratory effort; (3) reversal of hypotension; and (4) correction of an obtunded or comatose state.4


PEDIATRICS ◽  
1967 ◽  
Vol 39 (5) ◽  
pp. 771-774
Author(s):  
J. M. GUPTA ◽  
F. H. LOVEJOY

Twenty patients with phenothiazine toxicity admitted to the Children's Hospital Medical Center have been reviewed. In any patient presenting with bizarre neurological symptoms, phenothiazine toxicity should be borne in mind. Diphenhydramine (Benadryl) was found to be useful in both diagnosis and treatment. The use of phenothiazines in the treatment of acute nausea and vomiting in childhood is questioned.


PEDIATRICS ◽  
1972 ◽  
Vol 50 (3) ◽  
pp. 504-506

Conference on Newborn Infants: The University of Tennessee College of Medicine will present the Fourth Memphis Conference on the Newborn at the Holiday Inn-Rivermont, Memphis, Tennessee, on September 21, 1972. Faculty will include Drs. Marshall Klaus, Leo Stern, and Paul Swyer. For further information write the Division of Continuing Education and Conferences, The University of Tennessee Medical Units, 800 Madison Avenue, Memphis, Tennessee 38103. Problems in Pediatric Cardiology: The American Heart Association Council on Clinical Cardiology, the Council on Rheumatic Fever and Congenital Heart Disease, and the Departments of Pediatrics, Surgery, and Pathology of Children's Hospital Medical Center and Harvard Medical School, in cooperation with the Massachusetts Heart Association, will cosponsor a course: Problems in Pediatric Cardiology, September 25-27, 1972, at Children's Hospital Medical Center, Boston, Massachusetts.


PEDIATRICS ◽  
1974 ◽  
Vol 54 (5) ◽  
pp. 655-656
Author(s):  
Sanford Sherman

Pediatrics has obviously placed Dr. Lorber's commentary (53:307, 1974) and Dr. Freeman's paper (53:311, 1974) in a prominent position in order to provoke response. I hereby rise to the "bait." At Children's Hospital Medical Center in Oakland, California, there is an active program for managing spina bifida. Our clinic, which meets weekly, has the regular attendance of a pediatrician, neurosurgeon, orthopedists, urologist, physical therapist, occupational therapist, social worker, Public Health nurse and brace maker. Our ten-year experience is small compared with Dr. Lorber's and others, but it has had great continuity of professional personnel.


PEDIATRICS ◽  
1972 ◽  
Vol 49 (5) ◽  
pp. 787-788
Author(s):  
Gerald S. Golden ◽  
Gerald Erenberg

In a recent article, Tefft1 has stated that radioactive brain scans must be used to evaluate each child with a convulsive disorder, including those with a normal neurological examination and a normal or nonspecific electroencephalogram. He states that this should be done to rule out the presence of a low grade intracranial neoplasm or arteriovenous malformation. We would like to present three objections to this blanket policy. First, the yield would be extremely low. Follow up of children with epilepsy detected gliomas in 23 of 10,450 children (0.3%) in the study by Page, et al.2 and in 3 of 1,518 (0.2%) studied by Livingston.3


1965 ◽  
Vol 66 (2) ◽  
pp. 443-452 ◽  
Author(s):  
Sidney Farber ◽  
Gordon F. Vawter

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