scholarly journals Die sozialräumliche Struktur der LEADER-Region Vorderland-Walgau-Bludenz – Auf dem Weg zur alpinen Postsuburbia?

2020 ◽  
Vol 1 ◽  
pp. 35-62
Author(s):  
Johannes Herburger
Keyword(s):  
Leader Region

Importance of the leader region of mRNA for translation initiation of ColE2 Rep protein

Plasmid ◽  
2007 ◽  
Vol 58 (3) ◽  
pp. 249-260 ◽  
Author(s):  
Tomomi Nagase ◽  
Shin-ya Nishio ◽  
Tateo Itoh
Keyword(s):  
Translation Initiation ◽  
Leader Region ◽  
Rep Protein

scholarly journals Tetracycline Induces Stabilization of mRNA in Bacillus subtilis

2002 ◽  
Vol 184 (4) ◽  
pp. 889-894 ◽  
Author(s):  
Yi Wei ◽  
David H. Bechhofer
Keyword(s):  
Bacillus Subtilis ◽  
Mrna Stability ◽  
The Other ◽  
Leader Region ◽  
Subinhibitory Concentration ◽  
Coding Sequence ◽  
Mrna Stabilization ◽  
Threefold Increase ◽  
The Stability

ABSTRACT The tet(L) gene of Bacillus subtilis confers low-level tetracycline (Tc) resistance. Previous work examining the >20-fold-inducible expression of tet(L) by Tc demonstrated a 12-fold translational induction. Here we show that the other component of tet(L) induction is at the level of mRNA stabilization. Addition of a subinhibitory concentration of Tc results in a two- to threefold increase in tet(L) mRNA stability. Using a plasmid-borne derivative of tet(L) with a large in-frame deletion of the coding sequence, the mechanism of Tc-induced stability was explored by measuring the decay of tet(L) mRNAs carrying specific mutations in the leader region. The results of these experiments, as well as experiments with a B. subtilis strain that is resistant to Tc due to a mutation in the ribosomal S10 protein, suggest different mechanisms for the effects of Tc on translation and on mRNA stability. The key role of the 5" end in determining mRNA stability was confirmed in these experiments. Surprisingly, the stability of several other B. subtilis mRNAs was also induced by Tc, which indicates that addition of Tc may result in a general stabilization of mRNA.

Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Krüppel

1990 ◽  
Vol 10 (8) ◽  
pp. 4401-4405 ◽  
Author(s):  
N Kato ◽  
K Shimotohno ◽  
D VanLeeuwen ◽  
M Cohen
Keyword(s):  
Amino Acid ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Genomic Sequences ◽  
Cdna Clones ◽  
Leader Region ◽  
Rna Transcripts ◽  
Finger Protein

RNA transcripts of the HERV-R (ERV3) human provirus that are abundant in placenta but absent in choriocarcinoma contain nonproviral genomic sequences at their 3' ends. We report here the isolation of cDNA clones of these genomic sequences. The transcripts encode a Krüppel-related zinc finger protein consisting of a unique leader region and more than 12 28-amino-acid finger motifs.

Transcriptional and translational control through the 5′-leader region of thedmpRmaster regulatory gene of phenol metabolism

2014 ◽  
Vol 17 (1) ◽  
pp. 119-133 ◽  
Author(s):  
Anjana Madhushani ◽  
Teresa del Peso-Santos ◽  
Renata Moreno ◽  
Fernando Rojo ◽  
Victoria Shingler
Keyword(s):  
Translational Control ◽  
Regulatory Gene ◽  
Leader Region
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