Severe atopic dermatitis in a boy with potato allergy

Food allergy is an important problem in the paediatric population. Food products that are most likely to induce allergic reactions include cow’s milk, wheat, peanuts, hen’s eggs, fish and seafood. Food-allergy-related diseases include, among other things, atopic dermatitis, urticaria and asthma. Anaphylactic shock is the most severe form of allergic reaction. Intramuscular adrenalin at a dose of 0.01 mg/kg body weight (maximum dose 0.3–0.5 mg) is the primary treatment for anaphylaxis. An elimination diet is the treatment of choice in food allergy. If symptoms persist despite dietary intervention, extended diagnosis using skin prick tests and/or specific IgE measurements should be performed. We present a clinical case of a 2.5-year-old boy with erythroderma secondary to atopic dermatitis, who was referred to our Department due to the lack of improvement after outpatient treatment. It was found during hospital stay that the symptoms were caused by potato allergens.

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Unexpected Cat Allergy in Infants with Persistent Atopic Dermatitis

Journal of Dr Behcet Uz Children s Hospital ◽

10.5222/buchd.2021.26213 ◽

2021 ◽

Author(s):

Serdar Al ◽

Suna Asilsoy ◽

Özden Anal ◽

Dilek Tezcan ◽

Seda Şirin Köse ◽

...

Keyword(s):

Atopic Dermatitis ◽

Food Allergy ◽

Allergic Diseases ◽

Specific Ige ◽

Elimination Diet ◽

Severe Atopic Dermatitis ◽

Barrier Dysfunction ◽

Prick Test ◽

Cat Allergy ◽

History Of

Atopic dermatitis is a chronic, recurrent inflammatory skin disease usually caused by genetic predisposition, immune dysregulation, epidermal barrier dysfunction and interaction of environmental factors. Atopic dermatitis is part of atopic march and is often accompanied by food allergy. Aeroallergenic sensitization at early age is not an expected finding. Here, we present five cases with moderate-severe atopic dermatitis during infancy, in whom food allergy was detected and the symptoms improved only partially despite elimination and treatment. Sensitization was investigated in patients with a history of intense exposure to cats by specific IgE and skin prick test in infants with atopic dermatitis who had food allergy and persistant findings. Egg allergy was detected in four of the cases, wheat allergy in one. Cat allergy was present in all. Elimination diet was started in all cases. When exposure to cats was reduced, a marked improvement in the findings of atopic dermatitis was observed in all cases. Allergic diseases are increasing day by day. Unexpected aeroallergenic sensitization is now more common in the early stages of life. Allergic patients, regardless of age, should be questioned in detail for aeroallergen exposure. If it is detected; necessary preventive measures should be taken.

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Skin Manifestations of Food Allergy

PEDIATRICS ◽

10.1542/peds.111.s3.1617 ◽

2003 ◽

Vol 111 (Supplement_3) ◽

pp. 1617-1624 ◽

Cited By ~ 3

Author(s):

Wesley Burks

Keyword(s):

Atopic Dermatitis ◽

Food Allergy ◽

Specific Ige ◽

Rational Approach ◽

Severe Atopic Dermatitis ◽

Acute Urticaria ◽

Skin Response ◽

Allergic Skin ◽

Food Challenges ◽

Food Specific Ige

The pediatrician is faced with evaluating a panoply of skin rashes, a subset of which may be induced by food allergy. Acute urticaria is a common manifestation of an allergic skin response to food, but food is rarely a cause of chronic urticaria. Approximately one third of infants/children with moderate to severe atopic dermatitis have food allergy. Although diagnosis of acute urticaria provoked by a food may be evident from a straightforward history and confirmed by diagnostic tests to detect food-specific IgE antibody, determination of the role of food allergy in patients with atopic dermatitis is more difficult and may require additional diagnostic maneuvers, including elimination diets and oral food challenges. The immunopathologic basis of food-allergic disorders that affect the skin and a rational approach to diagnosis and treatment are discussed. Additional disorders that are caused by or mimic ones caused by food allergy are reviewed.

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FEATURES OF DIET THERAPY IN INFANTS WITH POLYVALENTFOOD ALLERGY

Rossiiskii Allergologicheskii ZHurnal ◽

10.36691/rja921 ◽

2010 ◽

Vol 7 (6) ◽

pp. 60-63

Author(s):

A N Pampura ◽

E E Varlamov

Keyword(s):

Atopic Dermatitis ◽

Food Allergy ◽

Amino Acid ◽

Challenge Test ◽

Specific Ige ◽

Elimination Diet ◽

Food Protein ◽

Oral Challenge Test ◽

Protein Intolerance ◽

Amino Acid Formula

Background. Establish indications for prescription of amino acid formula to infants with atopic dermatitis. Methods. 55 infants with atopic dermatitis and food allergy were enrolled. Allergic examination included skin prick tests and evaluation of specific IgE level. Oral challenge test was performed if necessary. Results. Low efficacy of elimination diet was observed in 16 infants with multiple food protein intolerance. In the issue cluster analysis defined two subgroups. High IgE levels, specific IgE to egg and fish were considered as criterions of the first subgroup. Patients with multiple food protein intolerance and low efficacy to elimination diet received amino acid formula, SCORAD index decreased more than 50% after the first week of treatment. Conclusion. Multiple food protein intolerance is particular form of food allergy. Prescription of amino acid formula is reasonable in this category of patients.

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Addressing Common Misconceptions in Food Allergy: A Review

Children ◽

10.3390/children8060497 ◽

2021 ◽

Vol 8 (6) ◽

pp. 497

Author(s):

Aikaterini Anagnostou

Keyword(s):

Food Allergy ◽

The United States ◽

Specific Ige ◽

Oral Immunotherapy ◽

Food Allergies ◽

Allergy Prevention ◽

Diagnosis And Management ◽

Skin Prick Tests ◽

Food Specific Ige ◽

Common Misconceptions

Background: Food allergies are common, affecting 1 in 13 school children in the United States and their prevalence is increasing. Many misconceptions exist with regards to food allergy prevention, diagnosis and management. Objective: The main objective of this review is to address misconceptions with regards to food allergies and discuss the optimal, evidence-based approach for patients who carry this diagnosis. Observations: Common misconceptions in terms of food allergy prevention include beliefs that breastfeeding and delayed introduction of allergenic foods prevent the development of food allergies. In terms of diagnosis, statements such as ‘larger skin prick tests or/and higher levels of food-specific IgE can predict the severity of food-induced allergic reactions’, or ‘Tryptase is always elevated in food-induced anaphylaxis’ are inaccurate. Additionally, egg allergy is not a contraindication for receiving the influenza vaccine, food-allergy related fatalities are rare and peanut oral immunotherapy, despite reported benefits, is not a cure for food allergies. Finally, not all infants with eczema will develop food allergies and epinephrine auto-injectors may unfortunately be both unavailable and underused in food-triggered anaphylaxis. Conclusions and relevance: Healthcare professionals must be familiar with recent evidence in the food allergy field and avoid common misunderstandings that may negatively affect prevention, diagnosis and management of this chronic disease.

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Dupilumab in Moderate-to-Severe Atopic Dermatitis With or Without Comorbid Food Allergy: Pooled Analysis of 2 Randomized Phase 3 Trials (LIBERTY AD SOLO 1 & 2)

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2017.12.418 ◽

2018 ◽

Vol 141 (2) ◽

pp. AB131

Author(s):

Eric L. Simpson ◽

Jean-Philippe Lacour ◽

Jonathan I. Silverberg ◽

Margitta Worm ◽

Andreas Wollenberg ◽

...

Keyword(s):

Atopic Dermatitis ◽

Food Allergy ◽

Pooled Analysis ◽

Severe Atopic Dermatitis ◽

Phase 3

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Diagnostic and Therapeutic Principles In Allergy

10.2310/im.1067 ◽

2018 ◽

Author(s):

Mitchell H. Grayson ◽

Peter Mustillo

Keyword(s):

Food Allergy ◽

Immunoglobulin E ◽

Skin Testing ◽

Allergic Sensitization ◽

Allergic Diseases ◽

Specific Ige ◽

Severe Form ◽

Therapeutic Principles ◽

Anticytokine Therapy ◽

Release Assay

The incidence of allergic diseases, like asthma, allergic rhinitis, and food allergy, is increasing in Westernized countries. This chapter discusses the importance of taking a careful and focused history and physical examination, as well as the laboratory studies that can be used to demonstrate the presence of allergic sensitization. Treatment for allergic disease is discussed, with an emphasis on new biologic therapies that have been developed. Finally, the chapter explores relatively new studies on the potential for interventions to prevent food allergy. Allergy is defined as an untoward physiologic event mediated by immune mechanisms, usually involving the interaction between an allergen and the allergic antibody, immunoglobulin E (IgE). Allergic reactions typically occur due to exposure to either airborne allergens, foods, drugs, chemicals, or Hymenoptera (such as wasps, bees and fire ants). Allergies manifest in numerous ways, including allergic asthma, allergic rhinoconjunctivitis, urticaria, eczema, and in its most severe form, anaphylaxis. This review contains 4 videos, 5 figures, 4 tables and 42 references Key Words: Delayed allergic reaction (Alpha-gal), Allergy diagnosis, Measurement of specific IgE, Allergy and asthma therapies, Anticytokine therapy (dupilumab, mepolizumab, reslizumab), AntiIgE therapy (omalizumab), Allergy skin testing, Basophil histamine release assay

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