Skin Manifestations of Food Allergy

PEDIATRICS ◽  
2003 ◽  
Vol 111 (Supplement_3) ◽  
pp. 1617-1624 ◽  
Author(s):  
Wesley Burks
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Specific Ige ◽  
Rational Approach ◽  
Severe Atopic Dermatitis ◽  
Acute Urticaria ◽  
Skin Response ◽  
Allergic Skin ◽  
Food Challenges ◽  
Food Specific Ige

The pediatrician is faced with evaluating a panoply of skin rashes, a subset of which may be induced by food allergy. Acute urticaria is a common manifestation of an allergic skin response to food, but food is rarely a cause of chronic urticaria. Approximately one third of infants/children with moderate to severe atopic dermatitis have food allergy. Although diagnosis of acute urticaria provoked by a food may be evident from a straightforward history and confirmed by diagnostic tests to detect food-specific IgE antibody, determination of the role of food allergy in patients with atopic dermatitis is more difficult and may require additional diagnostic maneuvers, including elimination diets and oral food challenges. The immunopathologic basis of food-allergic disorders that affect the skin and a rational approach to diagnosis and treatment are discussed. Additional disorders that are caused by or mimic ones caused by food allergy are reviewed.

Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements

PEDIATRICS ◽  
2015 ◽  
Vol 136 (6) ◽  
pp. e1530-e1538 ◽  
Author(s):  
J. M. Spergel ◽  
M. Boguniewicz ◽  
L. Schneider ◽  
J. M. Hanifin ◽  
A. S. Paller ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Specific Ige ◽  
Food Specific Ige

scholarly journals Severe atopic dermatitis in a boy with potato allergy

2020 ◽  
Vol 16 (3) ◽  
pp. 301-305
Author(s):  
Jędrzej Przekora ◽  
◽  
Agata Wawrzyniak ◽  
Anna Bujnowska ◽  
Agnieszka Rustecka ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Dietary Intervention ◽  
Paediatric Population ◽  
Specific Ige ◽  
Primary Treatment ◽  
Elimination Diet ◽  
Severe Form ◽  
Severe Atopic Dermatitis ◽  
Skin Prick Tests

Food allergy is an important problem in the paediatric population. Food products that are most likely to induce allergic reactions include cow’s milk, wheat, peanuts, hen’s eggs, fish and seafood. Food-allergy-related diseases include, among other things, atopic dermatitis, urticaria and asthma. Anaphylactic shock is the most severe form of allergic reaction. Intramuscular adrenalin at a dose of 0.01 mg/kg body weight (maximum dose 0.3–0.5 mg) is the primary treatment for anaphylaxis. An elimination diet is the treatment of choice in food allergy. If symptoms persist despite dietary intervention, extended diagnosis using skin prick tests and/or specific IgE measurements should be performed. We present a clinical case of a 2.5-year-old boy with erythroderma secondary to atopic dermatitis, who was referred to our Department due to the lack of improvement after outpatient treatment. It was found during hospital stay that the symptoms were caused by potato allergens.

Food allergy

2018 ◽  
Author(s):  
John Puntis
Keyword(s):  
Food Allergy ◽  
Nasal Congestion ◽  
Skin Prick Testing ◽  
Clinical History ◽  
Specific Ige ◽  
Cow Milk ◽  
Severe Reaction ◽  
Detailed Clinical History ◽  
Food Challenges ◽  
Food Specific Ige

Food allergy is an immune response to food that can be classified as immunoglobulin (Ig)-E and non-IgE mediated. Milk, egg, peanut, tree nuts, and fish are among the most prevalent causes of food allergy. Mild reactions can include itchy rash, watering eyes, and nasal congestion while a severe reaction results in anaphylaxis. A detailed clinical history is essential when making a diagnosis, and skin prick testing and quantitative measurement of food-specific IgE antibodies can be helpful. Cow milk protein allergy causes a plethora of symptoms and frequently resolves spontaneously over the first 2 years of life; diagnosis is based mainly on clinical history. Food challenges have a pivotal role in the diagnosis of food allergy. Introduction of ‘allergic’ foods at 3–6 months alongside continuing breastfeeding may prevent allergy.

scholarly journals Unexpected Cat Allergy in Infants with Persistent Atopic Dermatitis

2021 ◽  
Author(s):  
Serdar Al ◽  
Suna Asilsoy ◽  
Özden Anal ◽  
Dilek Tezcan ◽  
Seda Şirin Köse ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Elimination Diet ◽  
Severe Atopic Dermatitis ◽  
Barrier Dysfunction ◽  
Prick Test ◽  
Cat Allergy ◽  
History Of

Atopic dermatitis is a chronic, recurrent inflammatory skin disease usually caused by genetic predisposition, immune dysregulation, epidermal barrier dysfunction and interaction of environmental factors. Atopic dermatitis is part of atopic march and is often accompanied by food allergy. Aeroallergenic sensitization at early age is not an expected finding. Here, we present five cases with moderate-severe atopic dermatitis during infancy, in whom food allergy was detected and the symptoms improved only partially despite elimination and treatment. Sensitization was investigated in patients with a history of intense exposure to cats by specific IgE and skin prick test in infants with atopic dermatitis who had food allergy and persistant findings. Egg allergy was detected in four of the cases, wheat allergy in one. Cat allergy was present in all. Elimination diet was started in all cases. When exposure to cats was reduced, a marked improvement in the findings of atopic dermatitis was observed in all cases. Allergic diseases are increasing day by day. Unexpected aeroallergenic sensitization is now more common in the early stages of life. Allergic patients, regardless of age, should be questioned in detail for aeroallergen exposure. If it is detected; necessary preventive measures should be taken.

scholarly journals Addressing Common Misconceptions in Food Allergy: A Review

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 497
Author(s):  
Aikaterini Anagnostou
Keyword(s):  
Food Allergy ◽  
The United States ◽  
Specific Ige ◽  
Oral Immunotherapy ◽  
Food Allergies ◽  
Allergy Prevention ◽  
Diagnosis And Management ◽  
Skin Prick Tests ◽  
Food Specific Ige ◽  
Common Misconceptions

Background: Food allergies are common, affecting 1 in 13 school children in the United States and their prevalence is increasing. Many misconceptions exist with regards to food allergy prevention, diagnosis and management. Objective: The main objective of this review is to address misconceptions with regards to food allergies and discuss the optimal, evidence-based approach for patients who carry this diagnosis. Observations: Common misconceptions in terms of food allergy prevention include beliefs that breastfeeding and delayed introduction of allergenic foods prevent the development of food allergies. In terms of diagnosis, statements such as ‘larger skin prick tests or/and higher levels of food-specific IgE can predict the severity of food-induced allergic reactions’, or ‘Tryptase is always elevated in food-induced anaphylaxis’ are inaccurate. Additionally, egg allergy is not a contraindication for receiving the influenza vaccine, food-allergy related fatalities are rare and peanut oral immunotherapy, despite reported benefits, is not a cure for food allergies. Finally, not all infants with eczema will develop food allergies and epinephrine auto-injectors may unfortunately be both unavailable and underused in food-triggered anaphylaxis. Conclusions and relevance: Healthcare professionals must be familiar with recent evidence in the food allergy field and avoid common misunderstandings that may negatively affect prevention, diagnosis and management of this chronic disease.

Racial Differences In The Relationship Of Total and Food-Specific IgE To Atopic Dermatitis In Childhood

2014 ◽  
Vol 133 (2) ◽  
pp. AB196
Author(s):  
Gillian Bassirpour ◽  
Edward M. Zoratti ◽  
Ganesa Wegienka ◽  
Suzanne Havstad ◽  
Alexandra Sitarik ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Racial Differences ◽  
Specific Ige ◽  
Food Specific Ige ◽  
Relationship Of ◽  
The Relationship

scholarly journals Dupilumab in Moderate-to-Severe Atopic Dermatitis With or Without Comorbid Food Allergy: Pooled Analysis of 2 Randomized Phase 3 Trials (LIBERTY AD SOLO 1 & 2)

2018 ◽  
Vol 141 (2) ◽  
pp. AB131
Author(s):  
Eric L. Simpson ◽  
Jean-Philippe Lacour ◽  
Jonathan I. Silverberg ◽  
Margitta Worm ◽  
Andreas Wollenberg ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Pooled Analysis ◽  
Severe Atopic Dermatitis ◽  
Phase 3
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