scholarly journals A nyelv necrosisa mint az arteritis temporalis szokatlan manifesztációja

2017 ◽  
Vol 158 (2) ◽  
pp. 77-80
Author(s):  
Zoltán Sámson ◽  
Beáta Gábor ◽  
Petra Görög ◽  
Csaba Tóth ◽  
Ákos Rőthy ◽  
...  
Keyword(s):  
Temporal Arteritis ◽  
Clinical Course ◽  
Corticosteroid Treatment ◽  
Disease Pathogenesis ◽  
Rare Manifestation ◽  
Diagnostic Difficulties ◽  
Arteritis Temporalis

Abstract: Authors present a rare manifestation of the temporal arteritis, wich caused initial diagnostic difficulties, but it responded well for corticosteroid treatment. The features of the disease, pathogenesis, possible therapy are briefly summarized beside the description of clinical course. Orv. Hetil., 2017, 158(2), 77–80.

Eosinophilic enteritis – case report of a rare manifestation and review of updates

2020 ◽  
Vol 74 (6) ◽  
pp. 492-496
Author(s):  
Eliška Hloušková ◽  
Kateřina Bajerová ◽  
Jakub Pecl ◽  
Petr Jabandžiev ◽  
Marta Ježová ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Histopathological Examination ◽  
Corticosteroid Treatment ◽  
Elimination Diet ◽  
Eosinophilic Infiltration ◽  
Duodenal Wall ◽  
Dietary Restrictions ◽  
Rare Manifestation ◽  
Eosinophilic Gastrointestinal Disorders

Eosinophilic enteritis is one of the eosinophilic gastrointestinal disorders characterised by various clinical symptoms. Histopathologic proof of dense eosinophilic infiltration is the cornerstone for the diagnosis. There is no consensus on how dense the infiltration should be, and cut-off values of the eosinophilic count in HPF have not been defined yet. Therapy for eosinophilic enteritis is based on an elimination diet and corticosteroid treatment. Herein the authors report a case of 14-year-old boy who suffered from acute abdominal pain. Computer tomography of the abdomen revealed a thickening of the duodenal wall mimicking a tumour, which seemed to infiltrate the gallbladder and omentum. Histopathological examination of samples taken during laparoscopy showed eosinophilic infiltration and sclerotic changes of the gallbladder and duodenum. Follow-up endoscopy proved extensive eosinophilic infiltration of the gastrointestinal tract: eosinophilic esophagitis, duodenal ulcer with dense eosinophilic presence and eosinophilic proctitis. The patient recovered after dietary restrictions and prednisone.

scholarly journals Diagnostic Difficulties in a Case of Fetal Ventricular Tachycardia Associated with Neonatal COVID Infection: Case Report

2021 ◽  
Vol 18 (23) ◽  
pp. 12796
Author(s):  
Liliana Gozar ◽  
Carmen Corina Șuteu ◽  
Dorottya Gabor-Miklosi ◽  
Andreea Cerghit-Paler ◽  
Amalia Făgărășan
Keyword(s):  
Ventricular Tachycardia ◽  
Myocardial Injury ◽  
Clinical Course ◽  
Myocardial Dysfunction ◽  
Pediatric Population ◽  
Left Ventricular ◽  
Rapid Progression ◽  
First Case ◽  
Diagnostic Difficulties ◽  
Fetal Tachyarrhythmia

The clinical course of COVID in the pediatric population is considered to be much milder when compared to adults; however, the occurrence of severe and fatal forms of the disease in children is non-negligible, especially in patients with comorbidities such as prematurity or cardiac disease. We report a case of a newborn with sotalol-controlled fetal ventricular tachycardia, who was postnatally diagnosed with COVID infection. The myocardial injury was sustained on the basis of pericardial effusion, left ventricular dysfunction, rapid progression to coronary artery dilation, and an arrhythmic storm. We believe that, in our case, there is a significant overlap between fetal ventricular tachycardia, associated with impaired left ventricular function, and COVID infection, diagnosed after birth; both factors contribute to the myocardial dysfunction with a fulminant clinical evolution. To our knowledge, this is the first case describing neonatal myocardial dysfunction associated with SARS-CoV infection complicating the clinical course of rare fetal tachyarrhythmia.

scholarly journals Incretin-Based Therapies Role in COVID-19 Era: Evolving Insights

2020 ◽  
Vol 25 (6) ◽  
pp. 494-496
Author(s):  
Anca Pantea Stoian ◽  
Nikolaos Papanas ◽  
Martin Prazny ◽  
Ali A. Rizvi ◽  
Manfredi Rizzo
Keyword(s):  
Scientific Community ◽  
Clinical Course ◽  
Mechanisms Of Action ◽  
Disease Pathogenesis ◽  
Prognostic Variables ◽  
Dipeptidyl Peptidase 4 ◽  
Treatment Regimens ◽  
Antidiabetic Treatment ◽  
Coronavirus Infection

The current coronavirus disease 2019 (COVID-19) pandemic has led the scientific community to breach new frontiers in the understanding of human physiology and disease pathogenesis. It has been hypothesized that the human dipeptidyl peptidase 4 (DPP4) enzyme receptor may be a functional target for the spike proteins of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Since DPP4-inhibitors are currently used for the treatment of patients with type-2 diabetes (T2DM), there is currently high interest in the possibility that these agents, or incretin-based therapies (IBTs) in general, may be of benefit against the new coronavirus infection. Diabetes is associated with increased COVID-19 severity and mortality, and accumulating evidence suggests that IBTs may favorably alter the clinical course of SARS-CoV-2 infection due to their inherent mechanisms of action. Further research into prognostic variables associated with various antidiabetic treatment regimens, and in particular the IBT, in patients with T2DM affected by the COVID-19 pandemic is therefore warranted.

scholarly journals Steroid-Induced Sigmoid Diverticular Perforation in a Patient with Temporal Arteritis: A Rare Clinical Pathology

2012 ◽  
Vol 5 ◽  
pp. CPath.S7924 ◽  
Author(s):  
Bulent Kaya ◽  
Orhan Aras ◽  
Orhan Bat ◽  
Nuriye Esen Bulut ◽  
Kemal Memisoglu
Keyword(s):  
Temporal Arteritis ◽  
Clinical Pathology ◽  
Corticosteroid Treatment ◽  
Term Treatment ◽  
Mucosal Barrier ◽  
Colon Perforation ◽  
Pathophysiological Mechanism ◽  
Long Term Treatment ◽  
Rheumatological Diseases

Corticosteroids are used in the treatment of many rheumatological diseases including temporal arteritis. The gastrointestinal perforation during corticosteroid treatment is a serious complication. Colon perforation after steroid use was first reported by Beck et al in 1950. 1 Although the pathophysiological mechanism is not understood clearly, it is claimed that steroids probably by disturbing the intestinal mucosal barrier, facilitate the intestinal perforation. The long term treatment with corticosteroids increases the risk of colon perforation. We are presenting a patient who was taking corticosteroid due to temporal arteritis for two years and operated with sigmoid diverticular perforation.

scholarly journals Effective and Safe Use of Glucocorticosteroids for Rescue of Late ARDS

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Paolo Diana ◽  
Dustin T. Money ◽  
Michael G. Gelvin ◽  
Nadia Lunardi
Keyword(s):  
Marked Improvement ◽  
Low Dose ◽  
Distress Syndrome ◽  
Clinical Course ◽  
Corticosteroid Treatment ◽  
Lung Compliance ◽  
Lung Mechanics ◽  
Extra Corporeal Membrane Oxygenation ◽  
Rescue Treatment ◽  
Refractory Hypoxemia

We describe a case of severe refractory hypoxemia requiring prolonged extra corporeal membrane oxygenation (ECMO) support in a case of postpartum acute respiratory distress syndrome (ARDS). The clinical course was marked by persistently poor lung compliance and several complications of ECMO, that is, significant hemolysis, hemothorax, and intracranial bleeding. We report marked improvement of lung mechanics and respiratory function, leading to accelerated separation from ECMO, following rescue administration of low dose methylprednisolone 24 days after the onset of ARDS. Corticosteroid treatment was safe and well tolerated. In contrast with the conclusions of the 2006 ARDS Network trial, our report establishes a case in support of the use of low dose methylprednisolone as a safe and effective rescue treatment option in selected subsets of patients with nonresolving ARDS.

Zungennekrose und unilaterale Erblindung infolge Arteritis temporalis

VASA ◽  
2001 ◽  
Vol 30 (3) ◽  
pp. 222-224 ◽  
Author(s):  
Alec Cikes ◽  
M. Depairon ◽  
R.-M. Jolidon ◽  
P. Wyss ◽  
H.-J. Lang
Keyword(s):  
Temporal Arteritis ◽  
Clinical Presentation ◽  
Temporal Artery ◽  
The Other ◽  
Unusual Complication ◽  
Prompt Treatment ◽  
Clinical Presentations ◽  
The Right ◽  
Arteritis Temporalis ◽  
Tongue Necrosis

While blindness is one of the typical clinical presentations of temporal arteritis, tongue necrosis, on the other hand, is an unusual complication of the disease. An 80 year old male patient presenting a sudden massive swelling of the tongue was admitted to the Hospital of Yverdon. The swelling rapidly progressed to a complete necrosis of the tongue within a few days. The clinical presentation, the dramatic evolution of the necrosis, and sudden unilateral blindness despite prompt treatment confirmed our diagnosis of temporal arteritis. However, all the examinations, including biopsy of the right temporal artery, remained non-specific for the disease. Our diagnosis was based on the unusual clinical presentation of the disease.

scholarly journals A Case of Disseminated Cryptococcal Infection and Concurrent Lung Tuberculosis in a Patient under Steroid Therapy for Interstitial Pneumonia

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Aoi Kuroda ◽  
Sadatomo Tasaka ◽  
Kazuma Yagi ◽  
Takao Mochimaru ◽  
Tetsuo Tani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Interstitial Pneumonia ◽  
Clinical Course ◽  
Corticosteroid Treatment ◽  
Cell Mediated Immunity ◽  
Cryptococcal Infection ◽  
Computed Tomography Images ◽  
Lung Tuberculosis ◽  
Immunodeficiency Virus ◽  
Concurrent Infections

Both disseminated cryptococcal infection and tuberculosis occur in hosts with impaired cell-mediated immunity, but there have been few reports about the concurrent infections in patients without human immunodeficiency virus infection. A 64-year-old man, who had been taking corticosteroids for interstitial pneumonia, was diagnosed with disseminated cryptococcal infection. While the patient was receiving anticryptococcal therapy, pulmonary tuberculosis also emerged. The patient developed acute exacerbation of interstitial pneumonia and passed away. Based on the patient’s clinical course, serial computed tomography images, and autopsy results, we believe that the preceding several months of corticosteroid treatment might have contributed to these coinfections in the lungs already vulnerable due to underlying fibrosis.

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