The replication of canine herpesvirus (CHV) induces apoptosis in canine kidney cell line: Short communication

2005 ◽  
Vol 53 (1) ◽  
pp. 147-151 ◽  
Author(s):  
O. Kim ◽  
S. J. Yi

The alphaherpesvirus canine herpesvirus (CHV) was tested in order to determine whether or not it has apoptotic potential. We have demonstrated that lytic replication of CHV resulted in induction of apoptosis. This phenomenon was confirmed using different techniques including in situ TUNEL assay and DNA laddering. The apoptotic activity of CHV might influence the pathobiology of this virus.

1980 ◽  
Vol 8 (4) ◽  
pp. 265-267
Author(s):  
Michael J. Browne ◽  
Gillian M. Sperrin ◽  
Malcolm R. Boyd

1981 ◽  
Vol 10 (2) ◽  
pp. 217-217
Author(s):  
Michael J. Brown ◽  
Gillian M. Sperrin ◽  
Malcolm R. Boyd

1979 ◽  
Vol 9 (2) ◽  
pp. 175-179
Author(s):  
H Meguro ◽  
J D Bryant ◽  
A E Torrence ◽  
P F Wright

By means of a continuous canine kidney cell line (MDCK), influenza viruses were rapidly isolated from specimens collected from patients with respiratory disease. The cell line proved more sensitive than either eggs or rhesus monkey cells for currently circulating influenza A and B strains. Influenza viruses caused a distinct cytopathology within 5 days of inoculation if trypsin-ethylenediamine-tetraacetic acid was incorporated into the medium. Sufficient hemagglutinin was produced on the initial tissue culture passage to allow direct identification of isolates by hemagglutinin inhibition tests. A variety of other respiratory viruses replicated in MDCK, and over a 10-month period 211 of 600 specimens (35%) yielded viruses.


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