Acute inferior myocardial infarction with severe thrombus formation in a young male patient with primary antiphospholipid syndrome

Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis and/or recurrent pregnancy loss in the presence of antiphospholipid (APL) antibodies. It is evaluated as APS when it develops associated with other systemic autoimmune diseases or primary APS if there is no concomitant disorder. In this study, we present a case of a 16-year-old male patient with primary APS. The patient was admitted with presumptive diagnosis of pneumonia, but multiple pulmonary thromboembolism (PTE) was observed on computerized tomography (CT) pulmonary angiography. APL antibodies positivity and thrombocytopenia developed in our patient. The patient was evaluated as primary APS since another etiology that could explain PTE was not found. Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases. We present here a young male patient with primary APS and PTE to contribute to the literature. The patient initially had pneumonia but later developed PTE and thrombocytopenia.

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False Lumen Catheterization in a Patient Who Has Type A Aortic Dissection That Mimics Acute Inferior Myocardial Infarction: A Case Report

The Heart Surgery Forum ◽

10.1532/hsf.1340 ◽

2015 ◽

Vol 18 (5) ◽

pp. 208

Author(s):

Erhan Kaya ◽

Hakan Fotbolcu ◽

Zeki Şimşek ◽

Ömer Işık

Keyword(s):

Myocardial Infarction ◽

Case Report ◽

Aortic Dissection ◽

Cardiac Catheterization ◽

False Lumen ◽

Type A ◽

Inferior Myocardial Infarction ◽

Type A Aortic Dissection ◽

Acute Inferior Myocardial Infarction ◽

Catheterization Procedure

We report a 61-year-old patient who suffered from a type A aortic dissection that mimicked an acute inferior myocardial infarction. During a routine cardiac catheterization procedure, diagnostic catheters can be inserted accidentally into the false lumen. Invasive cardiologists should keep this complication in mind.

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Case of an unusual diagnosis of primary antiphospholipid syndrome with multiple clinical complications

Oxford Medical Case Reports ◽

10.1093/omcr/omaa117 ◽

2020 ◽

Vol 2020 (12) ◽

Author(s):

Stathis Tsiakas ◽

Chrysanthi Skalioti ◽

Paraskevi Kotsi ◽

Ioannis Boletis ◽

Smaragdi Marinaki

Keyword(s):

Antiphospholipid Syndrome ◽

Thrombotic Event ◽

Renal Involvement ◽

Clinical Manifestations ◽

Young Male ◽

Multiple Organ ◽

Systemic Autoimmune Disease ◽

Antiphospholipid Antibody ◽

Primary Antiphospholipid Syndrome ◽

Wide Range

ABSTRACT Antiphospholipid syndrome (APS) is a systemic autoimmune disease defined by the presence of antiphospholipid antibodies in association with thrombotic events and/or obstetric complications. Renal involvement is not infrequent in both primary and secondary APS. Kidney manifestations comprise a wide range of clinical features, including hypertension, major renal vessel thrombosis or microvascular endothelial injury, also described as APS nephropathy. In the absence of a thrombotic event, clinical manifestations of APS are often non-specific. We recently encountered a case of primary APS in a young male with newly diagnosed hypertension and renal impairment. The diagnosis of APS was initially suspected by his kidney biopsy findings, when electron microscopy examination showed the features of chronic microangiopathy, and was later confirmed by a triple positive antiphospholipid antibody profile and multiple organ involvement.

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