Sperm proteomics: potential impact on male infertility treatment

2016 ◽  
Vol 13 (3) ◽  
pp. 285-296 ◽  
Author(s):  
Ashok Agarwal ◽  
Ricardo Pimenta Bertolla ◽  
Luna Samanta
Keyword(s):  
Male Infertility ◽  
Infertility Treatment ◽  
Potential Impact

scholarly journals Large bowel infarct following antegrade scrotal sclerotherapy for varicocele: A case report

2014 ◽  
Vol 8 (9-10) ◽  
pp. 641 ◽  
Author(s):  
Patrizio Vicini ◽  
Giovanni Battista Di Pierro ◽  
Pietro Grande ◽  
Giuseppe Voria ◽  
Gabriele Antonini ◽  
...  
Keyword(s):  
Case Report ◽  
Male Infertility ◽  
Surgical Approach ◽  
Large Bowel ◽  
Infertility Treatment ◽  
Colonic Resection ◽  
Venous Anastomosis ◽  
Mesenteric Veins ◽  
Minimal Invasiveness

Varicocele is the main cause of male infertility. Treatment stops continuous damage to spermatogenesis, thereby potentially improving fertility. Among all the available procedures, the antegrade scrotal sclerotherapy (ASS), a combined radiological-surgical approach first introduced by Tauber, is gaining more popularity due to its minimal invasiveness. We report the case of a 35-year-old man who was subjected to a colonic resection after antegrade scrotal sclerotherapy for varicocele. The procedure was necessary due to the embolization of venous anastomosis between the spermatic and mesenteric veins, which were not detectable at the preoperative phlebography.

Evaluation of male infertility treatment following Rhus coriaria extract administration on rats exposed to morphine

2020 ◽  
Vol 47 (8) ◽  
pp. 6073-6081
Author(s):  
Shiva Roshankhah ◽  
Mohammad Reza Gholami ◽  
Mohammad Reza Salahshoor
Keyword(s):  
Male Infertility ◽  
Infertility Treatment ◽  
Rhus Coriaria

scholarly journals Women's perceptions and experiences of the challenges in the process of male infertility treatment: A qualitative study

10.19082/4349 ◽  
2017 ◽  
Vol 9 (5) ◽  
pp. 4349-4356 ◽  
Author(s):  
Ali Taghipour ◽  
Fatemeh Zahra Karimi ◽  
Robab Latifnejad Roudsari ◽  
Seyed Ali Kimiaei ◽  
Seyed Reza Mazlom ◽  
...  
Keyword(s):  
Qualitative Study ◽  
Male Infertility ◽  
Infertility Treatment ◽  
Women’S Perceptions

scholarly journals 87 ANTIOXIDANT THERAPY IN MALE INFERTILITY TREATMENT

2010 ◽  
Vol 20 ◽  
pp. S35
Author(s):  
I.V. Vinogradov ◽  
L.M. Afanasyeva ◽  
M.Y. Gabliya ◽  
R.A. Alexeev
Keyword(s):  
Male Infertility ◽  
Infertility Treatment ◽  
Antioxidant Therapy

scholarly journals Incidence and impact of hyperviscosity on sperm parameters of Malawian men seeking assisted reproduction

2020 ◽  
Vol 20 (1) ◽  
pp. 1-3
Author(s):  
Fanuel Lampiao ◽  
Joseph Chisaka
Keyword(s):  
Male Infertility ◽  
Sperm Motility ◽  
Volume Concentration ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Infertility Treatment ◽  
Normal Morphology ◽  
Progressive Motility ◽  
Accessory Sex Glands ◽  
Semen Volume

Background: Seminal hyperviscosity has been shown to be associated with male infertility. The aim of this study was to assess the prevalence of hyperviscosity in semen of Malawian males seeking infertility treatment. Methods: A total of 120 men visiting our laboratory for fertility assessment donated semen samples. The semen samples were assessed for hyperviscosity, volume, concentration, total motility, progressive motility, viability, and morphology. Results: Out of the 120 samples analyzed, 34 samples were hyperviscous representing 28.3%. No significant statistical differ- ence in semen volume between samples with normal viscosity compared to those with hyperviscosity (p>0.05). Sperm concen- tration, progressive motility, total motility, viability, and normal morphology were significantly higher in the normal viscosity group when compared to the abnormal viscocity group (p<0.05). Conclusion: Hyperviscosity affects a significant number of men in Malawi and may be the cause of decreased fertility as it was associated with poor sperm concentration, total motility, progressive motility, viability, and morphology. Keywords: Viscosity; sperm motility; accessory sex glands; infertility; semen; semen analysis; spermatozoa.

Using miRNAs as diagnostic biomarkers for male infertility: opportunities and challenges

2020 ◽  
Vol 26 (4) ◽  
pp. 199-214 ◽  
Author(s):  
A Vashisht ◽  
G K Gahlay
Keyword(s):  
Male Infertility ◽  
Human Development ◽  
Infertility Treatment ◽  
Mirna Biogenesis ◽  
Testicular Development ◽  
Transcriptional Level ◽  
Diagnostic Biomarkers ◽  
Clinical Disorder ◽  
Epididymal Maturation ◽  
Non Coding Rnas

Abstract The non-coding genome has been extensively studied for its role in human development and diseases. MicroRNAs (miRNAs) are small non-coding RNAs, which can regulate the expression of hundreds of genes at the post-transcriptional level. Therefore, any defects in miRNA biogenesis or processing can affect the genes and have been linked to several diseases. Male infertility is a clinical disorder with a significant number of cases being idiopathic. Problems in spermatogenesis and epididymal maturation, testicular development, sperm maturation or migration contribute to male infertility, and many of these idiopathic cases are related to issues with the miRNAs which tightly regulate these processes. This review summarizes the recent research on various such miRNAs and puts together the candidate miRNAs that may be used as biomarkers for diagnosis. The development of strategies for male infertility treatment using anti-miRs or miRNA mimics is also discussed. Although promising, the development of miRNA diagnostics and therapeutics is challenging, and ways to overcome some of these challenges are also reviewed.

scholarly journals Male Subfertility; Challenges and advancement in the andrology clinic at Khyber Pakhtunkhwa, Pakistan

2021 ◽  
Vol 6 (6) ◽  
pp. 8-14
Author(s):  
Mir Abid Jan ◽  
Arshad Arshad ◽  
Majid Khan Kakakhel ◽  
Muhammad Hamid
Keyword(s):  
Male Infertility ◽  
Medical Treatment ◽  
Infertility Treatment ◽  
Infertile Male ◽  
Secondary Infertility ◽  
Male Subfertility ◽  
Mean Delay ◽  
Infertile Men ◽  
Male Patients ◽  
The Mean

Objective:  This study is aimed to discuss the challenges in dealing the infertile male and advances in the treatment of male infertility. Material and methods: The study included infertile male patients who presented to andrology outpatient as primary or secondary infertility between December 2018 and January 2021. The data detailed different aspects of challenges and advances in male infertility treatment. The data analysisone with SPSS. Results: Total 289 patients included, most of them (74%) presented as primary infertility and a quarter presented as secondary infertility. The mean delay in presentation was 6.8 years which were due to treatment from non-andrologist doctors of different specialities (53.9%), hakims (15.2%), quacks (13.8%), gynaecologists (10.3%) and some were reluctant to tell their problem (6.5%). The diagnosis was N.O.A (42.9%), unexplained infertility (24.2%), varicocele (22.8%), OA (6.2%), OAT syndrome (2.7%) and CABVD (1%). Different treatment option opted were vasography plus vasovasostomy or vasoepididmostomy (31.1%), ART (23.9%), MSV (22.8%) and medical treatment (22.1%). Vasography plus vasovasostomy or vasoepididmostomy and medical treatment were the available options provided. There was no ART facility and those who were counseled for referral either their unwillingness or cost resulted in a hurdle in their provision. Conclusion: There are still a number of challenges in treating infertile men. Recently provision of medical and microsurgical treatment at andrology clinic resulted in proper treatment of a large number of infertile men who previously received treatment from un- related facilities.

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