scholarly journals Plasma miR-1273g-3p acts as a potential biomarker for early Breast Ductal Cancer diagnosis

Author(s):  
Huan Guo ◽  
Xiangting Zeng ◽  
Haining Li ◽  
Yanxiang Guo ◽  
Tao Wang ◽  
...  
2021 ◽  
Author(s):  
Xiaolong Chen ◽  
Yuanyi Deng ◽  
Gaihua Cao ◽  
Yifan Xiong ◽  
Danqun Huo ◽  
...  

MicroRNA-21 (miR-21) has been considered as a potential biomarker for cancer diagnosis and prognosis due to its highly expressed in tumors. Here, an analytical method which integrates the multiple cascaded...


2019 ◽  
Vol 13 (1) ◽  
pp. 45-54 ◽  
Author(s):  
Hongbing Mei ◽  
Yuhan Liu ◽  
Qun Zhou ◽  
Kun Hu ◽  
Yuchen Liu

2016 ◽  
Vol 39 (5) ◽  
pp. 1716-1722 ◽  
Author(s):  
Ting Deng ◽  
Yaozong Yuan ◽  
Chunni Zhang ◽  
Chenyu Zhang ◽  
Weiyan Yao ◽  
...  

Background: The aim of this study was to identify novel microRNAs for potential use in the diagnosis of pancreatic cancer (PaC). Methods: A total of 1063 serum samples from 303 patients with PaC were collected, and the expression level of miR-25 was measured using quantitative real-time PCR (qRT-PCR). Results: We found that miR-25 had significant diagnostic value for the differential diagnosis of PaC in normal controls with an AUC (the area under the ROC curve) of 0.915 (95% CI: 0.893-0.937) that was significantly higher compared with an AUC of 0.725 for serum tumor marker carcinoembryonic antigen (CEA) and an AUC of 0.844 for CA19-9. Conclusions: These data suggest that serum miR-25 has strong potential as a novel biomarker for the early detection of PaC.


2020 ◽  
Vol 24 (4) ◽  
pp. 2392-2401 ◽  
Author(s):  
Wenjun Chen ◽  
Jing Song ◽  
Hongjun Bian ◽  
Xia Yang ◽  
Xiaoyu Xie ◽  
...  

2014 ◽  
Vol 13 (1) ◽  
pp. e204
Author(s):  
S. Giglio ◽  
C. De Nunzio ◽  
R. Cirombella ◽  
A. Tubaro ◽  
A. Vecchione

RSC Advances ◽  
2017 ◽  
Vol 7 (35) ◽  
pp. 21630-21637 ◽  
Author(s):  
Guijin Zhai ◽  
Liping Yang ◽  
Qun Luo ◽  
Kui Wu ◽  
Yao Zhao ◽  
...  

A serum phosphopeptide (DpSGEGDFLAEGGGVR) was demonstrated to be a potential biomarker for gastric cancer diagnosis, particularly for early stage cases.


Gene ◽  
2019 ◽  
Vol 687 ◽  
pp. 246-254 ◽  
Author(s):  
Huo Zhang ◽  
Mingxia Zhu ◽  
Xia Shan ◽  
Xin Zhou ◽  
Tongshan Wang ◽  
...  

Tumor Biology ◽  
2017 ◽  
Vol 39 (2) ◽  
pp. 101042831769220 ◽  
Author(s):  
Harsimran Sidhu ◽  
Neena Capalash

UHRF1 is a master regulator of epigenome as it coordinates DNA methylation and histone modifications. Compelling evidence suggests a strong link between UHRF1 overexpression and tumorigenesis, substantiating its ability to act as a potential biomarker for cancer diagnosis and prognosis. UHRF1 also mediates repair of damaged DNA that makes cancer cells resistant toward cytocidal drugs. Hence, understanding the molecular mechanism of UHRF1 regulation would help in developing cancer therapeutics. Natural compounds have shown applicability to downregulate UHRF1 leading to growth arrest and apoptosis in cancer cells.


2016 ◽  
Vol 17 (8) ◽  
pp. 1-13
Author(s):  
Chao-Hui Zhen ◽  
Guo-Jun Yao ◽  
Yan Tan ◽  
Lu Yang ◽  
Xiao-Fang Yu ◽  
...  

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