scholarly journals Impulse control and related disorders in Parkinson’s disease

2018 ◽  
Vol 76 (6) ◽  
pp. 399-410 ◽  
Author(s):  
Antonio Pedro Vargas ◽  
Francisco Eduardo Costa Cardoso
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impulse Control ◽  
Gambling Disorder ◽  
Clinical Characteristics ◽  
Compulsive Buying ◽  
Compulsive Sexual Behavior ◽  
Dopamine Dysregulation Syndrome ◽  
Dopaminergic Stimulation ◽  
Stimulation Of

ABSTRACT Neuropsychiatric disorders are common among patients with Parkinson’s disease and may appear in any stage of the disease. However, these disorders often go undiagnosed and receive insufficient treatment. Observations in recent years have revealed that dopamine replacement therapy may lead to the development or worsening of conditions, such as gambling disorder, compulsive sexual behavior, compulsive buying and binge eating, in addition to punding and dopamine dysregulation syndrome. The pathophysiology of these disorders seems to be related to abnormal dopaminergic stimulation of the basal regions of the basal ganglia, especially via nigro-mesolimbic pathways. The aim of the present study was to perform a literature review on impulsivity, impulse control disorders and related conditions among patients with Parkinson’s disease, with emphasis on their epidemiology, clinical characteristics and treatment.

scholarly journals Impulse Control Disorders in Parkinson's Disease: Epidemiology, Pathogenesis and Therapeutic Strategies

2021 ◽  
Vol 12 ◽  
Author(s):  
Jun-Fang Zhang ◽  
Xi-Xi Wang ◽  
Ya Feng ◽  
Robert Fekete ◽  
Joseph Jankovic ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Broad Spectrum ◽  
Impulse Control ◽  
Compulsive Buying ◽  
Therapeutic Strategies ◽  
Impulse Control Disorders ◽  
Dopaminergic Therapy ◽  
Disease Epidemiology ◽  
Tremendous Impact

Impulse control disorders (ICDs) in Parkinson's disease (PD) are aberrant behavior such as pathological gambling, hypersexuality, binge eating, and compulsive buying, which typically occur as a result of dopaminergic therapy. Numerous studies have focused on the broad spectrum of ICDs-related behaviors and their tremendous impact on patients and their family members. Recent advances have improved our understanding of ICDs. In this review, we discuss the epidemiology, pathogenesis and treatment of ICDs in the setting of PD.

scholarly journals Impulsive and Compulsive Behaviors in Parkinson's Disease:

2014 ◽  
Vol 4 (1) ◽  
pp. 37-41
Author(s):  
Abdulraheem M. Alshehri
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impulse Control ◽  
Case Series ◽  
Impulse Control Disorders ◽  
Dopaminergic Therapy ◽  
Compulsive Eating ◽  
Dopamine Dysregulation Syndrome ◽  
Current Thinking ◽  
Compulsive Behaviors

Parkinson's disease is a common neurodegenerative disease, with a worldwide incidence of about 10-20 in 100,000. Its diagnosis remains clinical, and it requires bradykinesia plus one of the following: Rest tremor, rigidity or postural instability. Dopaminergic therapy including levodopa and dopamine agonists has allowed a reasonable control over the motor symptoms, but it offered no help for the non-motor manifestations. To the contrary, dopaminergic antiparkinson therapy was the most likely culprit in the emergence of a new set of impulse control disorders including:  Pathological gambling, hypersexuality, compulsive shopping, compulsive eating, punding (complex, repetitive, excessive, non-goal oriented behaviors), walkabout, and dopamine dysregulation syndrome. A case series of three main impulse control disorders in Parkinson's disease is presented here with a review of the current thinking regarding diagnosis and treatment.

scholarly journals Impact of Impulse Control Disorders on Sleep-Wake Regulation in Parkinson’s Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Atbin Djamshidian ◽  
Werner Poewe ◽  
Birgit Högl
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impulse Control ◽  
Sleep Disturbances ◽  
Treatment Strategies ◽  
Compulsive Buying ◽  
Impulse Control Disorders ◽  
Underlying Mechanisms ◽  
The Relationship ◽  
Behavioural Addictions

Sleep disturbances are common in patients with Parkinson’s disease (PD) and are even more prevalent in patients with behavioural addictions, such as pathological gambling, compulsive sexual behaviour, compulsive buying, binge eating, punding, and the compulsive use of dopamine replacement therapy. An overview of the relationship between these impulse control disorders and sleep disturbances is given and potential underlying mechanisms and treatment strategies are covered.

Clinical characteristics of impulse control and repetitive behavior disorders in Parkinson’s disease

2012 ◽  
Vol 260 (2) ◽  
pp. 429-437 ◽  
Author(s):  
Juyeon Kim ◽  
Mijin Kim ◽  
Do Young Kwon ◽  
Woo-Keun Seo ◽  
Ji Hyun Kim ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Behavior Disorders ◽  
Impulse Control ◽  
Clinical Characteristics ◽  
Repetitive Behavior

scholarly journals Parkinson’s Disease Impulsive-Compulsive Disorders Questionnaire – Current Short (QUIP-CS) – Translation and validation of content of Portuguese Version

2017 ◽  
Vol 66 (2) ◽  
pp. 111-115 ◽  
Author(s):  
Débora Mascella Krieger ◽  
Sabrina Vilanova Cardoso ◽  
Wolnei Caumo ◽  
Guilherme Valença ◽  
Daniel Weintraub ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Gold Standard ◽  
Impulse Control ◽  
Neuropsychiatric Symptoms ◽  
Compulsive Buying ◽  
Portuguese Version ◽  
Back Translation ◽  
Compulsive Disorders ◽  
Translation And Validation

ABSTRACT Objective Parkinson’s disease (PD) management is usually successfully reached with proper pharmacological treatment. However, PD patients can manifest neuropsychiatric symptoms secondary to medical therapy, including impulse control disorders (ICD), presenting as pathological gambling, hypersexuality, compulsive buying, drinking or eating disorders. We translated and validated the Portuguese version of the gold-standard questionnaire Parkinson’s Disease Impulsive-Compulsive Disorders Questionnaire, or (QUIP) for identifying ICDs in PD patients. Methods Translation, back translation and submission to instrument developer was performed, that approved its new version comparing it to his original, validated version, with no loss of it’s original properties. Then, the Portuguese version was administered to 30 PD patients. They also were asked to rate from 1 to 5 the level of comprehensibility of the questions. Results The average level of comprehension was 4.06 ± 0.69 DP, considering 3 or more as acceptable. No patient has answered 1 or 2. Conclusion Our results on Portuguese version of QUIP-CS show that QUIP-CS translated and corrected version was easily understood and easily self-applied.

scholarly journals Impulsive and Compulsive Behaviors in Parkinson's Disease:

2014 ◽  
Vol 4 (1) ◽  
pp. 37-41
Author(s):  
Abdulraheem M. Alshehri
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Impulse Control ◽  
Case Series ◽  
Impulse Control Disorders ◽  
Dopaminergic Therapy ◽  
Compulsive Eating ◽  
Dopamine Dysregulation Syndrome ◽  
Current Thinking ◽  
Compulsive Behaviors

Parkinson's disease is a common neurodegenerative disease, with a worldwide incidence of about 10-20 in 100,000. Its diagnosis remains clinical, and it requires bradykinesia plus one of the following: Rest tremor, rigidity or postural instability. Dopaminergic therapy including levodopa and dopamine agonists has allowed a reasonable control over the motor symptoms, but it offered no help for the non-motor manifestations. To the contrary, dopaminergic antiparkinson therapy was the most likely culprit in the emergence of a new set of impulse control disorders including:  Pathological gambling, hypersexuality, compulsive shopping, compulsive eating, punding (complex, repetitive, excessive, non-goal oriented behaviors), walkabout, and dopamine dysregulation syndrome. A case series of three main impulse control disorders in Parkinson's disease is presented here with a review of the current thinking regarding diagnosis and treatment.

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