scholarly journals Quality of life and changes in the social dimension of hematopoietic stem cell transplants recipients

2021 ◽  
Vol 74 (1) ◽  
Author(s):  
Celina Angélica Mattos Machado ◽  
Angela da Costa Barcellos Marques ◽  
Luciana de Alcantara Nogueira ◽  
Bruna Eloise Lenhani ◽  
Jorge Vinicius Cestari Felix ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Allogeneic Transplantation ◽  
Social Dimension ◽  
Life Questionnaire ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
The Social ◽  
Significant Difference

ABSTRACT Objectives: to assess/correlate health-related quality of life with the social dimension of hematopoietic, autologous and allogeneic stem cell transplant patients in the three years post-transplant. Methods: longitudinal, observational study with 55 patients, in a reference hospital in Latin America, from September 2013 to February 2019, using the Quality of Life Questionnaire-Core and Functional Assessment Cancer Therapy Bone Marrow Transplantation. Results: A total of 71% underwent allogeneic transplantation. The social dimension had low averages since the baseline stage (55, 21) and low scores (56) for quality of life in pancytopenia. There was a significant positive correlation between social dimension, quality of life in pancytopenia (p<0.01) and follow-up after hospital discharge (p<0.00). There is a significant difference (p<0.00) throughout the stages, however, not in terms of the type of transplant (p>0.36/0.86). Conclusions: patients with better assessments in the social dimension have a better quality of life. Interventions focusing on the multidimensionality of the quality of life construct are necessary.

Assessment of quality of life three years from hematopoietic stem cell transplant

2021 ◽  
Vol 55 ◽  
Author(s):  
Angela da Costa Barcellos Marques ◽  
Celina Angélica Mattos Machado ◽  
Dabna Hellen Tomim ◽  
Paulo Ricardo Bittencourt Guimarães ◽  
Jorge Vinicius Cestari Felix ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Life Questionnaire ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Hematologic Cancer

ABSTRACT Objective: To assess the domains of quality of life related to hematologic cancer patient health in the first three years from autologous and allogeneic hematopoietic stem cell transplantation. Method: A prospective cohort from September 2013 to February 2019 at a reference service in Latin America with 55 patients. The instruments Quality of Life Questionnaire Core C30 and Functional Assessment Cancer Therapy – Bone Marrow Transplantation were used. For data analysis, Generalized Linear Mixed Model was used. Results: The domains global and overall quality of life presented the lowest scores in the pancytopenia phase: 59.3 and 91.4 in autologous, 55.3 and 90.3 in allogeneic. The mixed method analysis has shown that there was a significant change in scores between the phases throughout the treatment (p< 0.05). Conclusion: Health-related quality of life presented significant changes in the domains between the phases throughout time. Understanding these results enables nursing interventions directed at the domains which were damaged during treatment.

scholarly journals Quality of life concerns and depression among hematopoietic stem cell transplant survivors

2010 ◽  
Vol 19 (9) ◽  
pp. 1357-1365 ◽  
Author(s):  
Catherine E. Mosher ◽  
Katherine N. DuHamel ◽  
Christine Rini ◽  
Geoffrey Corner ◽  
Joanne Lam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Hematopoietic Stem Cell Transplant ◽  
Stem Cell Transplant ◽  
Cell Transplant ◽  
Hematopoietic Stem

VP111 Referral Center For Multiple Myeloma Patient Care

2017 ◽  
Vol 33 (S1) ◽  
pp. 201-201
Author(s):  
Indara Saccilotto ◽  
Rosane Bittencourt ◽  
Camila Fischer ◽  
Amanda Quevedo ◽  
Vania Hirakata ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Outcome Measure ◽  
Hematopoietic Stem ◽  
Significant Difference ◽  
Care Facilities

INTRODUCTION:Within the Brazilian Health System, Referral Centers (RCs) are care facilities that provide specialized services. The objective of this study was to evaluate the efficacy of care provided to patients with multiple myeloma (MM) at a specialized Referral Centers (Hospital de Clínicas de Porto Alegre Referral Center for Multiple Myeloma, CRMM-HCPA) and to compare quality of life between patients with MM treated at CRMM-HCPA and those treated at non-RC facilities.METHODS:A 6-month cohort study was conducted in patients with MM receiving thalidomide from the State Health Department and treated at CRMM-HCPA, and patients receiving treatment at other non-RC facilities. Thirty-two patients were included in the study, nineteen from CRMM-HCPA and thirteen from other institutions. To analyze the efficacy of care provided at CRMM-HCPA, the main outcome measure was the time from diagnosis to referral for autologous hematopoietic stem cell transplantation.This outcome measure was assessed using questionnaires specifically designed for this study. Quality of life was also assessed, using the Short-Form 36 Item Health Survey (SF-36) questionnaire.RESULTS:Time from MM diagnosis to referral for autologous hematopoietic stem cell transplantation in each group was measured only in patients aged 65 years (n = 25); of these, 15 were recruited from CRMM-HCPA and 10 from other institutions. In this analysis, there was a significant difference (p = .036) in time elapsed between diagnosis and referral for autologous hematopoietic stem cell transplantation, which was significantly shorter for patients treated at CRMM-HCPA (median, 9 months; Interquartile Range, IQR, 8.5–14.5) than for those treated elsewhere (median, 24 months; IQR, 16–24). On quality of life analysis, there was a significant difference in the Social Functioning, which relates to performance of social activities (p = .02).CONCLUSIONS:The Referral Centers model provided seems to be a more efficient treatment strategy as compared with other health care facilities, as it enabled a reduction in time to transplantation. Patients treated at CRMM-HCPA demonstrated greater ease in performing social activities, with less interference from physical or emotional problems.

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