Brazilian Protocol for Sexually Transmitted Infections, 2020: infections that cause genital ulcers

This study set out to investigate the influence of male circumcision and other factors on sexually transmitted infections in Botswana. A syndromic approach, which diagnoses a sexually transmitted infection based on the presence of urethral discharge or genital ulcers rather than on laboratory tests, was used. The data were from the 2001 Botswana AIDS Impact Survey where a nationally representative, randomly selected sample of men and women aged 10–64 years were interviewed in both urban and rural areas. The sample selected for this study consisted of 216,480 men aged 15–64 years who had ever had sexual intercourse. The logistic regression technique was executed to examine the association between male circumcision and self-reported urethral discharge or genital ulcers, while controlling for all other independent variables in the analysis. The main finding of this study was that among men who are circumcised, the odds for self-reported urethral discharge or genital ulcers are significantly lower than for those men who are not circumcised in both urban and rural Botswana. The analysis also showed that the odds in favour of self-reported urethral discharge or genital ulcers, for men who drink alcohol, are twice as large as those for men who do not drink alcohol, controlling for all other independent variables in the analysis. Religion and ethnicity also came through as factors exerting a protective influence against self-reported symptoms of sexually transmitted infections. The conclusion is that while male circumcision appears to be significantly associated with the risk for self-reported urethral discharge or genital ulcers, it is man’s behaviour, irrespective of ethnicity or religious dictates, that continues to play a vital role in protection against self-reported symptoms of sexually transmitted infections in Botswana.

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Co-Occurrence of Chancroid and Gonorrhea

Journal of Cutaneous Medicine and Surgery ◽

10.1007/7140.2006.00002 ◽

2006 ◽

Vol 10 (1) ◽

pp. 41-44 ◽

Cited By ~ 2

Author(s):

Al-Mutairi Nawaf ◽

Arun Joshi ◽

Mohammad Tayeh

Keyword(s):

Human Immunodeficiency Virus ◽

Sexually Transmitted Infections ◽

Treatment Options ◽

Single Exposure ◽

Sexually Transmitted ◽

Urethral Discharge ◽

Intramuscular Dose ◽

Immunodeficiency Virus ◽

The World ◽

Genital Ulcers

Background: Gonorrhea and chancroid are common sexually transmitted infections in many parts of the world. Still, cooccurrence of these two conditions is uncommonly reported. Objective: We present here a patient who presented with painful genital ulcers and urethral discharge simultaneously acquired from a single exposure, which turned out to be chancroid and gonorrhea, respectively. Both conditions responded well to a single intramuscular dose of ceftriaxone 250 mg. Conclusion: This report describes the uncommon occurrence of gonorrhea and chancroid in a patient. Clinical features, relevant investigations, treatment options of these two sexually transmitted infections, and possible implications in view of the human immunodeficiency virus (HIV) pandemic are briefly discussed.

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Syndromes Associated with Sexually Transmitted Infections

Canadian Journal of Infectious Diseases and Medical Microbiology ◽

10.1155/2005/216365 ◽

2005 ◽

Vol 16 (1) ◽

pp. 13-14 ◽

Cited By ~ 1

Author(s):

Max Chernesky ◽

David Patrick ◽

Rosanna Peeling

Keyword(s):

Human Papillomavirus ◽

Sexually Transmitted Infections ◽

Inflammatory Disease ◽

Transmitted Infection ◽

Sexually Transmitted ◽

Laboratory Services ◽

Appropriate Treatment ◽

Enteric Infections ◽

Genital Ulcers ◽

Microbial Agents

Excellent technologies have been developed to identify the specific microbial agents of chlamydia, gonorrhea, syphilis, herpes, chancroid, trichomoniasis, human papillomavirus and HIV infection. However, it is also crucial to recognize syndromes that may be caused by one or more sexually transmitted pathogens. When laboratory services are lacking or are inadequate to provide timely results to enable appropriate treatment, some patients must be managed and treated syndromically. Most Canadian laboratories should be able to provide diagnostic services to determine the etiology of syndromes such as cervicitis, urethritis, pelvic inflammatory disease, prostatitis, genital ulcers, sexually transmitted infection (STI)-related enteric infections, epididymitis, hepatitis, ophthalmia neonatorum, vulvovaginitis and vaginosis.

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Genital Ulcers and Concomitant Complaints in Men Attending a Sexually Transmitted Infections Clinic: Implications for Sexually Transmitted Infections Management

Sexually Transmitted Diseases ◽

10.1097/olq.0b013e31816a4f2e ◽

2008 ◽

Vol 35 (6) ◽

pp. 545-549 ◽

Cited By ~ 19

Author(s):

Nigel O’Farrell ◽

Linda Morison ◽

Prashini Moodley ◽

Keshree Pillay ◽

Trusha Vanmali ◽

...

Keyword(s):

Sexually Transmitted Infections ◽

Sexually Transmitted ◽

Genital Ulcers

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Sexually Transmitted Infections: Part I: Genital Bumps and Genital Ulcers

Pediatrics in Review ◽

10.1542/pir.2018-0261 ◽

2020 ◽

Vol 41 (9) ◽

pp. 455-468

Author(s):

Nupur Gupta

Keyword(s):

Sexually Transmitted Infections ◽

Sexually Transmitted ◽

Genital Ulcers

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Sexually Transmitted Infections and Genital Ulcers

Practical Guide to Oral Exams in Obstetrics and Gynecology ◽

10.1007/978-3-030-29669-8_33 ◽

2019 ◽

pp. 203-215

Author(s):

Görker Sel

Keyword(s):

Sexually Transmitted Infections ◽

Sexually Transmitted ◽

Genital Ulcers

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Penile eczema: Not all genital ulcers are sexually transmitted infections

International Journal of STD & AIDS ◽

10.1177/0956462419875553 ◽

2019 ◽

Vol 30 (14) ◽

pp. 1443-1445

Author(s):

John Verrinder Veasey ◽

Rebeca Ruppert

Keyword(s):

Complete Remission ◽

Early Diagnosis ◽

Sexually Transmitted Infections ◽

World Health ◽

Syndromic Management ◽

Sexually Transmitted ◽

The World ◽

Syndromic Approach ◽

Genital Ulcers ◽

Health Organization

The presence of genital lesions leads some physicians and patients to instinctively think of sexually transmitted infections (STIs). In parallel, the World Health Organization guides the use of syndromic management to provide early diagnosis and immediate treatment in cases of genital lesions with suspected STI. We present two cases of patients with genital lesions for months that were unsuccessfully treated with the STI syndromic approach. Well-conducted histories were fundamental for the discovery of the eczematous etiology of genital ulcers due to the use of topical products indicated by both physicians and patients themselves, and the established therapy led to complete remission of the condition within a few weeks.

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Estimating syphilis seroprevalence among patients in a sexually transmitted infections clinic in Lilongwe, Malawi

International Journal of STD & AIDS ◽

10.1177/0956462420906762 ◽

2020 ◽

Vol 31 (4) ◽

pp. 359-363

Author(s):

Jane S Chen ◽

Mitch Matoga ◽

Shiraz Khan ◽

Edward Jere ◽

Cecilia Massa ◽

...

Keyword(s):

Sexually Transmitted Infections ◽

Newly Diagnosed ◽

Syndromic Management ◽

Ulcer Disease ◽

Sexually Transmitted ◽

Genital Ulcer Disease ◽

Resource Limited ◽

Syphilis Screening ◽

Genital Ulcers ◽

Diagnostic Capabilities

The syndromic management of genital ulcer disease (GUD) misses asymptomatic syphilis cases but is widely utilized in resource-limited settings without diagnostic capabilities to ensure treatment for the most common etiologies of GUD. We used rapid serology tests for syphilis screening at a Malawian sexually transmitted infections clinic. The estimated seroprevalence was 9% and was highest among patients with genital ulcers (26%) and newly diagnosed HIV infection (19%). Rapid syphilis screening has the potential to increase syphilis detection, but accurate patient histories regarding syphilis diagnosis and prior treatment are needed.

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