scholarly journals WILLIAM ABRÃO SAAD: IN MEMORIAN TO THE GRAND MASTER OF HEPATIC SURGERY!

Author(s):  
Marcelo A. F. RIBEIRO-JR ◽  
Paulo HERMAN ◽  
Luiz Augusto Carneiro D`ALBUQUERQUE ◽  
Fabrício F. COELHO ◽  
Eleazar CHAIB ◽  
...  
Keyword(s):  
2021 ◽  
Vol 32 (5) ◽  
pp. S113
Author(s):  
M. Rupasinghe ◽  
V. Ramachandran ◽  
F. Al-Khouja ◽  
D. Fernando ◽  
F. Dayyani ◽  
...  

2021 ◽  
Author(s):  
Camila Dossi ◽  
Romina Vargas ◽  
Rodrigo Valenzuela ◽  
Luis Videla

Liver ischemia-reperfusion injury (IRI) is a phenomenon inherent to hepatic surgery that severely compromises the organ functionality, whose underlying mechanisms involve cellular and molecular interrelated processes leading to the development...


2005 ◽  
Vol 48 (2) ◽  
pp. 31-36 ◽  
Author(s):  
Herve Delingette ◽  
Nicholas Ayache

2009 ◽  
Vol 34 (4) ◽  
pp. 308-311 ◽  
Author(s):  
Robert Shontz ◽  
Venkateswara Karuparthy ◽  
Robert Temple ◽  
Timothy J. Brennan

2002 ◽  
Vol 9 (1) ◽  
pp. 67-79 ◽  
Author(s):  
Florencia G. Que ◽  
Juan M. Sarmiento ◽  
David M. Nagorney

Author(s):  
Mehmet Asim Ozer ◽  
Alper Uguz ◽  
Omer Vedat Unalp ◽  
Ahmet Coker ◽  
Figen Govsa ◽  
...  

HPB Surgery ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. 285-297 ◽  
Author(s):  
M. A. J. Moser ◽  
N. M. Kneteman ◽  
G. Y. Minuk

Despite recent advances in hepatic surgery, resection of the cirrhotic liver continues to be fraught with high morbidity and mortality rates. As a result, for many patients requiring resection of HCC the postoperative course is complicated and the probability of cure is diminished by coexisting cirrhosis. In this review, we discuss the characteristics of the cirrhotic liver which make it poorly tolerant of resection and the most common complications that follow such surgery. The main purpose of this paper is to review recent attempts to identify interventions that might be beneficial to cirrhotic patients undergoing resection. These interventions include assessment of liver reserve, advances in surgical technique, and improvement in liver function and regeneration.


2006 ◽  
Vol 24 (13) ◽  
pp. 2065-2072 ◽  
Author(s):  
Jean-Nicolas Vauthey ◽  
Timothy M. Pawlik ◽  
Dario Ribero ◽  
Tsung-Teh Wu ◽  
Daria Zorzi ◽  
...  

Purpose Chemotherapy before resection of hepatic colorectal metastases (CRM) may cause hepatic injury and affect postoperative outcome. Patients and Methods Four hundred six patients underwent hepatic resection of CRM between 1992 and 2005. Pathologic review of the nontumorous liver was performed using established criteria for steatosis, steatohepatitis, and sinusoidal injury. The effect of chemotherapy and liver injury on perioperative outcome was analyzed. Results One hundred fifty-eight patients (38.9%) received no preoperative chemotherapy, whereas 248 patients (61.1%) did. The median duration of chemotherapy was 16 weeks (range, 2 to 70 weeks). Chemotherapy consisted of fluoropyrimidine-based regimens (fluorouracil [FU] alone, 15.5%; irinotecan plus FU, 23.1%; and oxaliplatin plus FU, 19.5%) and other therapy (3.0%). On pathologic analysis, 36 patients (8.9%) had steatosis, 34 (8.4%) had steatohepatitis, and 22 (5.4%) had sinusoidal dilation. Oxaliplatin was associated with sinusoidal dilation compared with no chemotherapy (18.9% v 1.9%, respectively; P < .001; odds ratio [OR] = 8.3; 95% CI, 2.9 to 23.6). In contrast, irinotecan was associated with steatohepatitis compared with no chemotherapy (20.2% v 4.4%, respectively; P < .001; OR = 5.4; 95% CI, 2.2 to 13.5). Patients with steatohepatitis had an increased 90-day mortality compared with patients who did not have steatohepatitis (14.7% v 1.6%, respectively; P = .001; OR = 10.5; 95% CI, 2.0 to 36.4). Conclusion Steatohepatitis is associated with an increased 90-day mortality after hepatic surgery. In patients with hepatic CRM, the chemotherapy regimen should be carefully considered because the risk of hepatotoxicity is significant.


HPB ◽  
2013 ◽  
Vol 15 (7) ◽  
pp. 548-558 ◽  
Author(s):  
Robert Öllinger ◽  
Andre L. Mihaljevic ◽  
Christoph Schuhmacher ◽  
Hüseyin Bektas ◽  
Florian Vondran ◽  
...  

2014 ◽  
pp. 175-182
Author(s):  
Adrian W. Ong ◽  
Kusum Tom
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document