scholarly journals Influence Of Genetic Polymorphisms In Genes Of Bone Remodeling And Angiogenesis Process In The Apical Periodontitis

2018 ◽  
Vol 29 (2) ◽  
pp. 179-183 ◽  
Author(s):  
Jardel Francisco Mazzi-Chaves ◽  
Igor Bassi Ferreira Petean ◽  
Isadora Mello Vilarinho Soares ◽  
Alessandro Guimarães Salles ◽  
Lívia Azeredo Alves Antunes ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Root Canal ◽  
Apical Periodontitis ◽  
Genotype Distribution ◽  
Canal System ◽  
Root Canal Therapy ◽  
Angiogenesis Process ◽  
Root Canal System ◽  
Genotype And Allele Frequencies

Abstract Persistent apical periodontitis (AP) is a situation involving an inflammatory and immune response caused mainly by anaerobic polymicrobial infection of the root canal system and the outcome and follow-up of the root canal treatment has been reported as intimately related to host response. The apical periodontitis repair might be associated with genetic polymorphisms. This study aimed to evaluate the association between HIF1A genetic polymorphisms (rs2301113 and rs2057482) with PAP in Brazilian patients. Subjects with at least 1 year of follow-up after root canal therapy (RCT) were recalled. Sixty-four subjects with signs/symptoms of PAP and 84 subjects with root canal-treated teeth exhibiting healthy perirradicular tissues (healed) were included. Genomic DNA was extracted from saliva and used for HIF1A genotyping by real-time PCR. Genotype and allele frequencies were compared by c2 or Fisher’s exact tests and odds ratio was implemented, using Epi Info 3.5.2. All tests were performed with an established alpha of 0.05. There was no association between allele and genotype distribution for HIF1As polymorphisms and PAP (p>0.05). The genetic polymorphisms in HIF1A were not associated with persistent apical periodontitis.

scholarly journals Microbial infection and its control in cases of symptomatic apical periodontitis: A review

Medicina ◽  
2008 ◽  
Vol 45 (5) ◽  
pp. 343 ◽  
Author(s):  
Neringa Skučaitė ◽  
Vytautė Pečiulienė ◽  
Vita Mačiulskienė
Keyword(s):  
Host Resistance ◽  
Root Canal ◽  
Susceptibility Testing ◽  
Apical Periodontitis ◽  
Microbial Infection ◽  
Canal System ◽  
Root Canal Therapy ◽  
Dental Origin ◽  
Root Canal System ◽  
Selection Of

Apical periodontitis is an inflammation of dental periapical tissues developed as a response to colonization of microorganisms in root canal system. Etiology of periapical pathology is associated with different species of microorganisms that are not fully defined yet. The changes in the composition of root canal microbiota as well as other factors, such as host resistance to various infections and concomitant viral infection, etc., can influence development of the symptomatic apical periodontitis. Etiology of disease is reviewed in this article. The purpose of treatment of symptomatic apical periodontitis is to eliminate the infection in root canal system and to obtain relief of symptoms. It can be done by conventional root canal therapy, which can be combined with anti-inflammatory medication. Indications for antibiotic therapy in such cases are limited to particular occasions, which are considered in article. Nevertheless, findings show that usually dentists prescribe antibiotics improperly in clinical practice. It can render drugs ineffective against diseases of dental origin as well as against potentially fatal infectious diseases. Selection of antibiotics for the treatment of root canal infections is reviewed in this article. Importance of antimicrobial susceptibility testing is emphasized. There is a need for more research on microbial causes and interactions in different forms of apical periodontitis to improve diagnosis and treatment.

Chitosan-decorated calcium hydroxide microcapsules with pH-triggered release for endodontic applications

2015 ◽  
Vol 3 (45) ◽  
pp. 8884-8891 ◽  
Author(s):  
Xiaoman Li ◽  
Bing Han ◽  
Xiaoyan Wang ◽  
Xuejun Gao ◽  
Fuxin Liang ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Drug Toxicity ◽  
Apical Periodontitis ◽  
Canal System ◽  
Triggered Release ◽  
Root Canal Therapy ◽  
Root Canal System ◽  
Immune Factors

The treatment of apical periodontitis (AP) remains challenging because traditional root canal therapy (RCT) outcomes are limited by the complexity of the root canal system, drug toxicity, and host immune factors.

The Apical Root Canal System of Teeth with Posttreatment Apical Periodontitis: Correlating Microbiologic, Tomographic, and Histopathologic Findings

2020 ◽  
Vol 46 (9) ◽  
pp. 1195-1203 ◽  
Author(s):  
José F. Siqueira ◽  
Henrique S. Antunes ◽  
Alejandro R. Pérez ◽  
Flávio R.F. Alves ◽  
Ibrahimu Mdala ◽  
...  
Keyword(s):  
Root Canal ◽  
Apical Periodontitis ◽  
Canal System ◽  
Root Canal System ◽  
Histopathologic Findings ◽  
Posttreatment Apical Periodontitis

scholarly journals Endodontic Disinfection for Orthograde Root Canal Treatment in Veterinary Dentistry

2020 ◽  
Vol 37 (1) ◽  
pp. 35-40
Author(s):  
Laura Sasser
Keyword(s):  
Sodium Hypochlorite ◽  
Root Canal ◽  
Ethylenediaminetetraacetic Acid ◽  
Endodontic Treatment ◽  
Smear Layer ◽  
Canal System ◽  
Root Canal Therapy ◽  
Complex Anatomy ◽  
Root Canal System ◽  
Necrotic Debris

Pulp debridement and disinfection in the pulp cavity is a critical step in achieving a successful root canal therapy. Microorganisms remaining in the root canal system after endodontic treatment are a main cause of root canal failure. The challenges faced in endodontic disinfection include the complex anatomy of the root canal system, the existence of a biofilm within the root canal, and the creation of a problematic smear layer during instrumentation of the canal. Historically, sodium hypochlorite and ethylenediaminetetraacetic acid have been utilized as irrigants and still remain as the most effective disinfectants due to their synergistic abilities to eradicate microorganisms, dissolve necrotic debris, and remove the smear layer and biofilm. This article addresses challenges in endodontic disinfection, objectives of endodontic irrigants, properties of an ideal irrigant, currently used irrigants, and irrigant delivery systems utilized in veterinary dentistry.

scholarly journals Single visit apexification technique by root end barrier formation with MTA

2015 ◽  
Vol 5 (1) ◽  
pp. 21-25
Author(s):  
Tazdik G Chowdhury ◽  
SM Abdul Quader ◽  
Tasnim A Jannat ◽  
Shirin Sultana Chowdhury ◽  
KM Rowank Jahan ◽  
...  
Keyword(s):  
Root Canal ◽  
Paediatric Dentistry ◽  
Lateral Incisor ◽  
Periapical Lesion ◽  
Canal System ◽  
Single Visit ◽  
Barrier Formation ◽  
Root Canal System ◽  
One Year

Aim: To seal with Mineral trioxide aggragate(MTA) and make a sizeable communication between the root canal system and the periradicular tissue and provide a barrier because of lack of apical constriction.Summary: A 9 year old girl who had met with trauma about six years ago, before she visited department of Paediatric Dentistry , Update Dental College,Dhaka,Bangladesh for the treatment of mandibular right lateral incisor. The case was diagnosed as necrosis of pulp with open apex. After proper isolation access opening and biomechanical preparation was performed with 1mm short of the radiographic apex and calcium hydroxideused as intra canal medicament. After 15 days MTA was placed in the canal till a barrier of 4mm was achieved. Later obturation was done using lateral condensation technique.Size of the periapical lesion was almost decreased after one year of follow up. Followup was done after 1 month, 6 months and 1 year later.Update Dent. Coll. j: 2015; 5 (1): 21-25

scholarly journals Microbiota in the apical root canal system of tooth with apical periodontitis

BMC Genomics ◽  
2019 ◽  
Vol 20 (S2) ◽  
Author(s):  
Wenhao Qian ◽  
Ting Ma ◽  
Mao Ye ◽  
Zhiyao Li ◽  
Yuanhua Liu ◽  
...  
Keyword(s):  
Root Canal ◽  
Apical Periodontitis ◽  
Canal System ◽  
Root Canal System

scholarly journals Nonsurgical Retreatment of Lower Incisor with Apical Lesion

2014 ◽  
Vol 3 (2) ◽  
pp. 98-102
Author(s):  
Alberto Dagna
Keyword(s):  
Root Canal ◽  
Mineral Trioxide Aggregate ◽  
Canal System ◽  
Lower Incisor ◽  
Endodontic Surgery ◽  
Gutta Percha ◽  
First Choice ◽  
Root Canal System ◽  
The Right

ABSTRACT Orthograde retreatment is the first choice to manage an endodontic failure, because surgical approach not always eliminates from the root canal all those microorganisms that caused the failure. Endodontic surgery is commonly performed, when the root canal space is no longer accessible as a result of the presence coronal obstacles. But this case report demonstrates that the attempt to removal of prosthetic crown and post allows to create the right access and then to perform an adequate shaping, cleansing and sealing of the root canal system, even if the chronic periapical pathology induced an initial apical resorption. When the apical diameter is increased, perfect obturation with gutta-percha is not possible, and the apical sealing can be managed with mineral trioxide aggregate (MTA). Follow-up intraoral periapical radiograph at 20 months shows adequate repair of the periapical rarefaction. How to cite this article Dagna A, Saini R. Nonsurgical Retreatment of Lower Incisor with Apical Lesion. Int J Experiment Dent Sci 2014;3(2):98-102.

Disinfection of the root canal system: what should the protocol be?

Dental Update ◽  
2021 ◽  
Vol 48 (10) ◽  
pp. 836-844
Author(s):  
Stephen J Bonsor
Keyword(s):  
Root Canal ◽  
Aetiological Factor ◽  
Root Canal Preparation ◽  
Clinical Protocol ◽  
Canal System ◽  
Root Canal Therapy ◽  
Disinfection Methods ◽  
Organic Debris ◽  
Root Canal System ◽  
Micro Organisms

The presence of micro-organisms within the root canal system is the critical aetiological factor in peri-radicular periodontitis. During root canal treatment (RCT) it is imperative that this infection and other organic debris are removed from the root canal system. This is challenging because complex tooth anatomy, the presence of a biofilm and the smear layer complicate the process. There are a number of irrigant chemicals and adjunctive systems available in contemporary endodontic practice that are used to disinfect the root canal system during root canal preparation. This article reviews the available evidence concerning these disinfection methods and concludes by presenting a clinical protocol supported by the literature. CPD/Clinical Relevance: A clinical protocol, supported by the literature, is presented for effective decontamination of the root canal system during root canal therapy.

Part 1: “I would Rather have a Root Canal than...” Francis W Allen discusses the challenges of cleaning the canal thoroughly to minimize pain and ensure long-term success

2010 ◽  
Vol 1 (1) ◽  
pp. 21-29
Author(s):  
Francis W Allen
Keyword(s):  
Root Canal ◽  
The Other ◽  
Canal System ◽  
Root Canal Therapy ◽  
Light Speed ◽  
Instruments And Techniques ◽  
Root Canal System

ABSTRACT Cleaning and shaping of root canal system forms the most important step in root canal root canal therapy. Unfortunately most of the instruments and techniques advocated are unable to remove residual debris and bacteria, ultimately resulting in pain and failure. To eliminate the causes of pain, and ensure success, we must use instruments and employ a technique that can best accomplish proper cleaning and shaping. Virtually all canals have parallel walls, and are curved and oval in shape. Hence tapered instruments are unable to clean the canal effectively and increase the chances of ledges and transportation and extrusion of debris beyond the apex. With the introduction of Light Speed technology primary goal of endodontics which includes removal of debris safely and effectively can be achieved. This article focuses on the use of Light Speed technology to overcome the difficulties posed by the other instrumentation and techniques to achieve debris and bacteria free canal system.

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