scholarly journals Downer cow syndrome causing rhabdomyolysis and acute renal failure in a 17-month-old Guzerá heifer

2022 ◽  
Vol 52 (2) ◽  
Author(s):  
Teresa Souza Alves ◽  
Mariana da Costa Gonzaga ◽  
Igor Louzada Moreira ◽  
Mizael Machado ◽  
Davi Emanuel Ribeiro de Sousa ◽  
...  

ABSTRACT: The downer cow syndrome (DCS) is characterized by an alert cow showing inability or reluctance to stand for 12 hours or more. This paper reported clinical, laboratory, and pathological findings in a Guzerá heifer with rhabdomyolysis, pigmenturia and acute renal failure following DCS. A 17-month-old Guzerá heifer was transported via a 350-km ride in a truck and showed sternal recumbency and severe difficulty in standing and walking. Neurological examination was unremarkable, and the heifer presented normal response to cranial nerves and spinal cord tests. Rectal palpation revealed a 5-month gravid uterus. No other abnormalities were noted in the pelvis or around the coxofemoral joints. Biochemical abnormalities included extremely high muscular enzyme activities (creatine phosphokinase and aspartate aminotransferase) and high creatinine levels. Urinalysis revealed blackish and cloudy urine, proteinuria, and a positive occult blood test. Spinal cord ultrasonography showed no abnormalities. This report highlighted an uncommon clinical presentation (myoglobinuria) and pathological findings in a heifer with DCS as a consequence of severe compressive muscle damage. Practitioners and producers must be aware of the risk of careless road transportation for long distances of cattle, especially obese cows, avoiding unnecessary suffering and expenses due to DCS.

1982 ◽  
Vol 128 (4) ◽  
pp. 803-804 ◽  
Author(s):  
Frank L. D’Elia ◽  
Richard E. Brennan ◽  
P. Kenneth Brownstein

2008 ◽  
Vol 3;11 (5;3) ◽  
pp. 681-686
Author(s):  
Thomas M. Larkin

Objective: This is the first case describing an episode of acute renal failure occurring during a spinal cord stimulation trial. Clinical Presentation: A 48-year-old male with a history of hypertension and 3 prior failed spine surgeries underwent a trial of spinal cord stimulation for uncontrolled bilateral lower extremity neuropathic pain. Two days after the placement of the percutaneous stimulator lead the patient returned complaining of 3 syncopal episodes. He was found to be hypotensive and in acute renal failure with a creatinine of 8.1 and a BUN of 83. Intervention: The stimulator lead was immediately removed. The patient was admitted to the intensive care unit and responded promptly to rehydration and placement of a urinary catheter. His renal and urological work-ups revealed no significant abnormalities. Conclusion: The development of the episode of acute renal failure may have been influenced by the secondary effects of spinal cord stimulation. Since acute renal failure has never been associated with the use of spinal cord stimulation, this singular example does not by itself demonstrate a relationship. However, if future episodes are seen, a link between the 2 events could be drawn. For now, it is not clear if the development of this patient’s acute renal failure could, in part, be attributed to the use of the spinal cord stimulator or if it was merely coincidental in nature. We do feel it is useful for the clinician to understand the pathophysiologic changes associated with spinal cord stimulation and to see how, at least in theory, there could be a connection. Key words: acute renal failure, spinal cord stimulation


1996 ◽  
Vol 32 (6) ◽  
pp. 495-501 ◽  
Author(s):  
KR Harkin ◽  
CL Gartrell

The clinical, laboratory, and serological findings in 17 dogs with disease resulting from leptospiral infection were evaluated retrospectively. Acute renal failure was the most common syndrome, but cholestatic hepatic disease also was common. The most prevalent serovars identified were pomona, grippotyphosa, and autumnalis. Paired serology was available on 10 dogs. Aggressive fluid therapy in combination with ampicillin or amoxicillin resulted in a good survival rate. Canine leptospirosis may be more common than suspected, and paired serology often is necessary to confirm a diagnosis.


1990 ◽  
Vol 10 (5) ◽  
pp. 398-399
Author(s):  
H. L. C. Beynon ◽  
M. Alexander ◽  
P. Robson ◽  
C. D. Pusey ◽  
D. F. Hawkins

Author(s):  
Juliana De Moura Alonso ◽  
Carlos Alberto Hussni ◽  
Marcos Jun Watanabe ◽  
Ana Liz Garcia Alves ◽  
Marília Ferrari Marsiglia ◽  
...  

Neuropathies of pharyngeal branches of glossopharyngeal and vagus are often associated with guttural pouches diseases; however, these branches of injury due to stylopharyngeus muscle compression are not reported. A case was reported of a quarter horse mare, 8 years old, 450 kg, presenting dyspnea and respiratory noise associated with weight loss. Clinical examination observed mixed dyspnea, tachycardia, dysphagia, sialorrhea, lung crackles and submandibular and parotid lymphadenopathy. Endoscopic exam showed right arytenoid chondritis, nasopharyngeal collapse, generalized larynx edema and dorsal displacement of the soft palate. Right guttural pouch evaluation showed swelling in the origin of stylopharyngeus muscle with consequent compression of the XII, X and IX cranial nerves. Tracheotomy, systemic treatment with corticosteroids, beta lactams and aminoglycosides antibiotics were performed. No resolution was observed and, after 16 days, the animal showed clinical worsening, developed pleuropneumonia, uveitis, severe sepsis, acute renal failure and was euthanized. The mixed neuropathy resulted in rapid clinical deterioration of the animal, due to the difficulty in swallowing and consequent associated respiratory processes. This report emphasizes the importance of evaluating stylopharyngeus muscle origin in cases of nasopharyngeal collapse associated with dysphagia in horses, given the possibility that structural changes in this muscle can result in laryngeal neuropathy.


2005 ◽  
Vol 52 (3) ◽  
pp. 49-54 ◽  
Author(s):  
Lazar Davidovic ◽  
M. Markovic ◽  
R. Sindjelic ◽  
N. Savic ◽  
D. Kostic ◽  
...  

Objective: The aim of the study was to present the outcome of surgical treatment of patients with thoracoabdominal aortic aneurysm Crawford type IV, operated on between January 2001 and April 2004. Methods: This study included 42 subsequent patients (40 males, 2 females, age 41-76 years). All patients underwent ultrasonography, angiography, computed tomography or magnetic resonance imaging (MRI). Surgical treatment was performed under combined anesthesia (continuous thoracic epidural analgesia and general endotracheal anesthesia). In two patients thoracophrenolumbotomy was performed at the level of X rib, while others were operated through left lumbotomy after the extra pleural resection of XI rib. We did not perform any spinal cord protection procedures in this type of aneurysm. Reconstruction included interposition of Dacron graft in 20 patients, aortobiiliac bypass in 18, and aortobifemoral bypass in 4 patients with different varieties of visceral branches reimplantation. Results: Thirty - days mortality was 31% (13 patients, two of them intraoperatively). Causes of death were: pulmonary embolism - in 1 patient; hemorrhage - in 2; myocardial infarction - in 4 (two intraoperative); acute renal failure - in 2; multi system organ failure (MSOF) - in 4 patients. Respiratory failure dominated in all cases of MSOF. One patient with acute renal failure had paraplegia also, and that was the only case of neurological complication in whole group. All female patients (2), all patients with ruptured aneurysm (4), acute myocardial infarction (4) and acute renal failure (2) have died. Advanced age (over 70 years) and the need for extensive operative procedure with bifurcated graft use significantly influenced their mortality (p<0.01 and p<0.05 respectively). Conclusions: Surgical treatment of thoracoabdominal aortic aneurysm Crawford IV type was successful in 69% of our patients. There was no need for spinal cord protection measures, and extra peritoneal approach with XI rib resection under the combined anesthesia was preferred.


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