scholarly journals MEASUREMENT OF LOCAL CONSISTENCY OF THE WHOLE BRAIN AFTER AEROBIC EXERCISE BASED ON MAGNETIC RESONANCE IMAGING

2021 ◽  
Vol 27 (4) ◽  
pp. 425-429
Author(s):  
Feng Wang ◽  
Ailuan Huang

ABSTRACT Introduction: The rapid development of rs-fMRI in recent years can provide new scientific evidence of the plasticity of the child's brain. Objective: To reveal the effect of short-term moderate-intensity aerobic exercise on local consistency of brain function in children at rest, and to provide new evidence for elucidating the relationship between physical exercise and plasticity of children's brain. Methods: Using resting state functional magnetic resonance imaging (rs-fMRI) technology and local consistency (ReHo) analysis method to detect a 30-min short-term moderate-intensity aerobic exercise before and after children's brain function local consistency changes; using the Flanker task measurement Changes in children's executive function before and after exercise. Results: 1) A 30-min short-term moderate-intensity aerobic exercise made the children's bilateral posterior buckle back, left dorsolateral prefrontal lobe, left frontal medial gyrus, bilateral central posterior gyrus, left suboccipital gyrus, and tongue gyrus. 2) A 30-minute short-term moderate-intensity aerobic exercise improves children's executive function. 3) ReHo increases in bilateral posterior buckle gyrus, bilateral central parietal posterior gyrus, and left dorsal lateral prefrontal lobe are significantly associated with improved executive function. Conclusions: Short-term moderate-intensity aerobic exercise can improve brain plasticity and executive function by increasing local consistency of brain function in children at rest. Level of evidence II; Therapeutic studies - investigation of treatment results.

2019 ◽  
Vol 30 (4) ◽  
pp. 676-679
Author(s):  
Massimiliano Serafino ◽  
Matteo Scaramuzzi ◽  
Edoardo Villani ◽  
Paolo Nucci

Objective: To assess the efficacy of “Yokoyama Procedure,” on non-highly myopic patients with acquired esotropia and hypotropia. Methods: The study involved 10 eyes of 5 patients with eso-hypotropia. Inclusion criteria were acquired esotropic-hypotropic strabismus with lateral rectus inferior displacement and superior rectus nasal displacement confirmed by magnetic resonance imaging, refractive errors between ±6 D, and axial length < 27 mm. Range of full duction movements and maximum angles of abduction-sursumduction was measured in each eye before and after surgery. All patients underwent T1- and T2-weighted magnetic resonance imaging. The surgery was aimed at creating a junction between the muscle bellies of the superior and lateral rectus muscles. This junction was made approximately 14 mm behind the insertions using a non-absorbable mersilene 5/0 suture (Yokoyama procedure). Results: Mean patient age was 64.8 ± 4.8 years. The mean globe axial length was 25.4 ± 0.76 mm and a mean corresponding spherical equivalent refraction of −3.7 ± 1.7 D was observed. Eight eyes on 10 had mild limitation in abduction, while the remaining 2 had no limitation. Three out of 10 eyes showed a moderate limited sursumduction, 5 eyes were categorized as mild, and the remaining 2 had no limitation. No evident post-operative limitation was present in any eye, in both abduction and sursumduction (p < 0.01). Pre-operative esotropia and hypotropia were, respectively, 32 ± 11 prismatic diopters and 25 ± 5 prismatic diopters, and they were significantly reduced after surgery as 9 ± 1.7 prismatic diopters and 6 ±1 prismatic diopters (p = 0.043), respectively. Conclusion: Yokoyama procedure is an effective, fast, reversible procedure to face eso-hypotropic acquired strabismus, even in patients with a clear magnetic resonance imaging displacement of superior and lateral rectus muscles, and absence of globe dislocation and of elevated myopia.


Stroke ◽  
2004 ◽  
Vol 35 (2) ◽  
pp. 554-559 ◽  
Author(s):  
Kyung K. Peck ◽  
Anna B. Moore ◽  
Bruce A. Crosson ◽  
Megan Gaiefsky ◽  
Kaundinya S. Gopinath ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Mohammad Shahidi-Dadras ◽  
Fahimeh Abdollahimajd ◽  
Razieh Jahangard ◽  
Ali Javinani ◽  
Amir Ashraf-Ganjouei ◽  
...  

Background. Morphea is an inflammatory disease of the connective tissue that may lead to thickening and hardening of the skin due to fibrosis. The aim of this study was to document magnetic resonance imaging (MRI) changes in patients with linear morphea who were treated with methotrexate (MTX) and high-dose corticosteroid. Methods. This study was conducted on 33 patients from the outpatient’s dermatology clinic of our institute, who fulfilled the inclusion criteria. Patients received 15 mg/week of MTX and monthly pulses of methylprednisolone for three days in six months. The effectiveness of the treatment was evaluated by MRI, modified LS skin severity index (mLoSSI), and localized scleroderma damage index (LoSDI). Results. All parameters of mLoSSI and LoSDI including erythema, skin thickness, new lesion/lesion extension, dermal atrophy, subcutaneous atrophy, and dyspigmentation were also noticeably improved after treatment. Subcutaneous fat enhancement was the most common finding in MRI. MRI scores were significantly associated with clinical markers both before and after the treatment with the exception of skin thickness and new lesion/lesion extension which were not associated with MRI scores before and after the treatment, respectively. Limitations. The lack of correlative laboratory disease activity markers, control group, and clearly defined criteria to judge the MRI changes. Conclusion. MRI could be a promising tool for the assessment of musculoskeletal and dermal involvement and also monitoring treatment response in patients with morphea.


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