Short-Term Comparison of Magnetic Resonance Imaging and Spectroscopy in Persistent Canine Hepatic Encephalopathy Before and After Treatment

Author(s):  
Mario Dolera ◽  
Luca Malfassi ◽  
Cristina Bianchi ◽  
Nancy Carrara ◽  
Sara Finesso ◽  
...  
2021 ◽  
Vol 27 (4) ◽  
pp. 425-429
Author(s):  
Feng Wang ◽  
Ailuan Huang

ABSTRACT Introduction: The rapid development of rs-fMRI in recent years can provide new scientific evidence of the plasticity of the child's brain. Objective: To reveal the effect of short-term moderate-intensity aerobic exercise on local consistency of brain function in children at rest, and to provide new evidence for elucidating the relationship between physical exercise and plasticity of children's brain. Methods: Using resting state functional magnetic resonance imaging (rs-fMRI) technology and local consistency (ReHo) analysis method to detect a 30-min short-term moderate-intensity aerobic exercise before and after children's brain function local consistency changes; using the Flanker task measurement Changes in children's executive function before and after exercise. Results: 1) A 30-min short-term moderate-intensity aerobic exercise made the children's bilateral posterior buckle back, left dorsolateral prefrontal lobe, left frontal medial gyrus, bilateral central posterior gyrus, left suboccipital gyrus, and tongue gyrus. 2) A 30-minute short-term moderate-intensity aerobic exercise improves children's executive function. 3) ReHo increases in bilateral posterior buckle gyrus, bilateral central parietal posterior gyrus, and left dorsal lateral prefrontal lobe are significantly associated with improved executive function. Conclusions: Short-term moderate-intensity aerobic exercise can improve brain plasticity and executive function by increasing local consistency of brain function in children at rest. Level of evidence II; Therapeutic studies - investigation of treatment results.


1993 ◽  
Vol 21 (4) ◽  
pp. 411-425
Author(s):  
Manfred Brauer

Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) give anatomical and biochemical information about a human patient or animal in a non-invasive manner. This unique quality permits the study of toxicological responses of an organ within an intact animal and in a manner in which many fewer animals are needed than by conventional methods of investigation. The use of MRI and MRS in the study of hepatotoxicants, particularly bromobenzene and ethanol, is reviewed. Bromobenzene causes localised hepatic oedema and bioenergetic deterioration; these changes were followed with time by 1H MRI and 31P MRS, respectively. Phosphocholine levels in the liver were found to increase dramatically during bromobenzene-induced damage, possibly related to an intracellular control mechanism in response to tissue damage. The ability of the bromobenzene-challenged liver to metabolise a fructose load was followed by dynamic 31P MRS. Chronic ethanol administration damages the liver. This toxicological process results in the accumulation of fat in the liver, which was followed by fat-selective 1H MRI. When ethanol is no longer administered to the subject, the fatty infiltration subsides, and this process was followed over 16 days in the same animal using fat-selective 1H MRI. Chronic ethanol renders the liver in situ more susceptible to hypoxic injury and less likely to recover afterwards, as shown by 31P MRS.


2019 ◽  
Vol 30 (4) ◽  
pp. 676-679
Author(s):  
Massimiliano Serafino ◽  
Matteo Scaramuzzi ◽  
Edoardo Villani ◽  
Paolo Nucci

Objective: To assess the efficacy of “Yokoyama Procedure,” on non-highly myopic patients with acquired esotropia and hypotropia. Methods: The study involved 10 eyes of 5 patients with eso-hypotropia. Inclusion criteria were acquired esotropic-hypotropic strabismus with lateral rectus inferior displacement and superior rectus nasal displacement confirmed by magnetic resonance imaging, refractive errors between ±6 D, and axial length < 27 mm. Range of full duction movements and maximum angles of abduction-sursumduction was measured in each eye before and after surgery. All patients underwent T1- and T2-weighted magnetic resonance imaging. The surgery was aimed at creating a junction between the muscle bellies of the superior and lateral rectus muscles. This junction was made approximately 14 mm behind the insertions using a non-absorbable mersilene 5/0 suture (Yokoyama procedure). Results: Mean patient age was 64.8 ± 4.8 years. The mean globe axial length was 25.4 ± 0.76 mm and a mean corresponding spherical equivalent refraction of −3.7 ± 1.7 D was observed. Eight eyes on 10 had mild limitation in abduction, while the remaining 2 had no limitation. Three out of 10 eyes showed a moderate limited sursumduction, 5 eyes were categorized as mild, and the remaining 2 had no limitation. No evident post-operative limitation was present in any eye, in both abduction and sursumduction (p < 0.01). Pre-operative esotropia and hypotropia were, respectively, 32 ± 11 prismatic diopters and 25 ± 5 prismatic diopters, and they were significantly reduced after surgery as 9 ± 1.7 prismatic diopters and 6 ±1 prismatic diopters (p = 0.043), respectively. Conclusion: Yokoyama procedure is an effective, fast, reversible procedure to face eso-hypotropic acquired strabismus, even in patients with a clear magnetic resonance imaging displacement of superior and lateral rectus muscles, and absence of globe dislocation and of elevated myopia.


Stroke ◽  
2004 ◽  
Vol 35 (2) ◽  
pp. 554-559 ◽  
Author(s):  
Kyung K. Peck ◽  
Anna B. Moore ◽  
Bruce A. Crosson ◽  
Megan Gaiefsky ◽  
Kaundinya S. Gopinath ◽  
...  

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