scholarly journals Impulsiveness and executive functions in Parkinson’s disease

2019 ◽  
Vol 13 (4) ◽  
pp. 410-414 ◽  
Author(s):  
Bruna de Assis Almeida ◽  
Amer Cavalheiro Hamdan
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Executive Functions ◽  
Cognitive Functions ◽  
Cognitive Assessment ◽  
Correlation Study ◽  
Frontal Assessment Battery ◽  
A Value ◽  
Demographic Questionnaire ◽  
The Relationship

ABSTRACT Cognitive functions, such as impulsiveness and executive functions, are often impaired in Parkinson’s disease. Objective: to analyze the relationship between impulsiveness and executive functions (EF) in people with Parkinson’s disease (PD). Methods: a correlation study involving a sample of 50 patients with an established diagnosis of PD aged 40 years or older was conducted using the following instruments: Demographic Questionnaire, Montreal Cognitive Assessment Basic (MOCA-B), Barratt’s Impulsiveness Scale (BIS-11) and Frontal Assessment Battery (FAB). Results: Pearson’s correlation analysis indicated low associations (p<0.05) between the MOCA-B and BIS-11, with a value of -0.11, and between the FAB and BIS-11, with a value of -0.16. A significant correlation between the MOCA-B and FAB was found, with a value of 0.73. Conclusion: this study revealed an association between EF and other cognitive functions, but no association between impulsivity and EF in Parkinson’s disease.

Theory of mind and executive functions in normal human aging and Parkinson's disease

2000 ◽  
Vol 6 (7) ◽  
pp. 781-788 ◽  
Author(s):  
JENNIFER SALTZMAN ◽  
ESTHER STRAUSS ◽  
MICHAEL HUNTER ◽  
SARAH ARCHIBALD
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Theory Of Mind ◽  
Executive Functions ◽  
Right Hemisphere ◽  
Human Aging ◽  
Brain Functions ◽  
Normal Human ◽  
Relationship Of ◽  
The Relationship

Although the majority of research in theory of mind (TOM) has focused on young children or individuals with autism, recent investigations have begun to look at TOM throughout the lifespan and in other neurological and psychiatric populations. Some have suggested that TOM may represent a dissociable, modular brain system that is related to, but separable, from other brain functions including executive functions (EF). Recently, studies have shown that TOM performance can be compromised following an acquired brain insult (e.g, damage to the right hemisphere). However, the relationship of such impaired TOM performance to other brain functions in these cases has not been explored. This study investigated the effects of both normal human aging and Parkinson's disease on TOM. The relationship of TOM performance and EF in these groups was also examined. The results suggested that although TOM performance appeared compromised in the group of individuals with Parkinson's disease, the elderly control participants were relatively unimpaired relative to younger individuals. Significant relationships between several measures of TOM and EF were also found. The implications of these findings, and also the finding that failure on one measure of TOM did not necessarily predict failure on all measures of TOM, are discussed. (JINS, 2000, 6, 781–788.)

Disentangling the relationship between cognitive estimation abilities and executive functions: a study on patients with Parkinson’s disease

2015 ◽  
Vol 36 (8) ◽  
pp. 1425-1429 ◽  
Author(s):  
Guido Edoardo D’Aniello ◽  
Federica Scarpina ◽  
Giovanni Albani ◽  
Gianluca Castelnuovo ◽  
Alessandro Mauro
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Executive Functions ◽  
Cognitive Estimation ◽  
The Relationship

scholarly journals The impact of poor medication knowledge on health-related quality of life in people with Parkinson’s disease: a mediation analysis

2021 ◽  
Author(s):  
Hannah M. Zipprich ◽  
Sarah Mendorf ◽  
Aline Schönenberg ◽  
Tino Prell
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Assessment ◽  
Medication Knowledge ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

Abstract Purpose This study aimed to determine how limited medication knowledge as one aspect of health literacy contributes to poorer health-related quality of life (HRQoL) in people with Parkinson’s disease (PD). Methods Demographical data, PD-specific data (MDS-Unified Parkinson’s Disease-Rating Scale, Nonmotor symptom scale), and data about depressive symptoms (Beck’s depression inventory), cognition (Montreal cognitive assessment), HRQoL (Short-Form Health Questionnaire-36, SF-36), and medication knowledge (names, time of taking, indication, dosage) were assessed in 193 patients with PD. Multivariate analysis of variance (MANOVA), multivariate analysis of covariance, and mediation analyses were used to study the relationship between medication knowledge and HRQoL in combination with different mediators and covariates. Results Overall, 43.5% patients showed deficits in at least one of the 4 knowledge items, which was associated with higher age, number of medications per day and depression level, and poorer cognitive function, motor function, and lower education level. Using one-way MANOVA, we identified that medication knowledge significantly impacts physical functioning, social functioning, role limitations due to physical problems, and role limitations due to emotional problems. Mediation models using age, education level, and gender as covariates showed that the relationship between knowledge and SF-36 domains was fully mediated by Beck’s Depression Inventory but not by Montreal Cognitive Assessment. Conclusions Patients who expressed unawareness of their medication did not necessarily have cognitive deficits; however, depressive symptoms may instead be present. This concomitant depressive symptomatology is crucial in explaining the contribution of nonadherence and decreased medication knowledge to poor quality of life.

scholarly journals The Relationship Between Serotonin-2A Receptor and Cognitive Functions in Nondemented Parkinson's Disease Patients with Visual Hallucinations

2017 ◽  
Vol 4 (5) ◽  
pp. 698-709 ◽  
Author(s):  
Sang Soo Cho ◽  
Antonio P. Strafella ◽  
Sarah Duff-Canning ◽  
Mateusz Zurowski ◽  
Anne-Catherine Vijverman ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Functions ◽  
Visual Hallucinations ◽  
Serotonin 2A Receptor ◽  
The Relationship ◽  
Serotonin 2A

scholarly journals Exercise and cognitive functions in Parkinson's disease: Gender differences and disease severity

2014 ◽  
Vol 20 (4) ◽  
pp. 461-469 ◽  
Author(s):  
Claudia Teixeira-Arroyo ◽  
Natália Madalena Rinaldi ◽  
Rosangela Alice Batistela ◽  
Fabio Augusto Barbieri ◽  
Rodrigo Vitório ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Episodic Memory ◽  
Executive Functions ◽  
Disease Severity ◽  
Cognitive Functions ◽  
Exercise Program ◽  
Preventive Strategy ◽  
Immediate Memory ◽  
Before And After

This study investigated the effect of a multimodal exercise program on executive functions and memory in people with Parkinson's disease, taking into account disease severity and gender. Twenty-three patients with Parkinson's disease (PD) were evaluated before and after a 6-month exercise program to improve executive functions and memory. We observed the effects of the intervention on executive functions (ability to abstract: p = .01), immediate memory (p= .04) and declarative episodic memory (p < .001). Women showed higher scores on declarative episodic memory (p = .03) than men, however there was no interaction between gender and the intervention. Regardless of sex and disease severity, these preliminary results indicate that the multimodal exercise seems to be effective in improving cognitive functions in patients with PD, suggesting that this program can be indicated as a preventive strategy to mitigate progressive cognitive deficits in the later stages of the disease.

scholarly journals Association between sleep disorders and cognitive dysfunctions in non-demented patients with advanced Parkinson’s disease

2021 ◽  
Author(s):  
Elisa Montanaro ◽  
Alberto Romagnolo ◽  
Margherita Fabbri ◽  
Carlo Alberto Artusi ◽  
Gabriele Imbalzano ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Executive Functions ◽  
Daytime Sleepiness ◽  
Sleep Disturbances ◽  
Short Term Memory ◽  
Sleep Problems ◽  
Neuropsychological Test ◽  
Neuropsychological Functions ◽  
The Relationship

Abstract Background Parkinson’s disease (PD) is increasingly recognized as a multidimensional disorder, characterized by several non-motor symptoms, including disturbances of sleep and cognition. Current studies on the relationship between sleep problems and neuropsychological functions, mainly conducted in early to moderate PD patients, outline mixed results. In this study, we analysed the relationship between subjectively reported sleep alterations and cognitive functions in a large cohort of 181 advanced PD patients. Methods All consecutive, non-demented, advanced PD patients candidates for device-aided therapy completed two self-administered sleep questionnaires—the Parkinson’s Disease Sleep Scale (PDSS-2) and the Epworth Sleepiness Scale (ESS)—and underwent a comprehensive battery of neuropsychological tests encompassing five cognitive domains (reasoning, memory, attention, frontal executive functions, and language). Results Patients showed mild to moderate sleep problems (PDSS-2 score: 23.4 ± 1.2) and mild daytime sleepiness (ESS 8.6 ± 5.1). A significant correlation was found between PDSS-2 total score and non-verbal reasoning, as well as attentive skills, executive functions, and language abilities. No correlations were found between sleep measures and memory tests scores. Patients with clinically relevant sleep disturbances performed worse on attention, executive functions, and language. No significant correlations were found between daytime sleepiness and any neuropsychological test. Conclusions In advanced PD patients, sleep disturbances selectively correlate with specific neuropsychological functions and not with short-term memory and consolidation. Even if confirmations by means of longitudinal studies are needed, our observations suggest the importance of considering treatment of sleep disturbances to minimize their potential impact on cognition.

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