scholarly journals Recanalization after acute deep vein thrombosis

2013 ◽  
Vol 12 (4) ◽  
pp. 296-302 ◽  
Author(s):  
Gustavo Mucoucah Sampaio Brandao ◽  
Marcone Lima Sobreira ◽  
Hamilton Almeida Rollo
Keyword(s):  
Deep Vein Thrombosis ◽  
Vessel Wall ◽  
Lower Limbs ◽  
Venous Disease ◽  
Natural Evolution ◽  
Vein Thrombosis ◽  
Complex Process ◽  
History Of ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

The process of recanalization of the veins of the lower limbs after an episode of acute deep venous thrombosis is part of the natural evolution of the remodeling of the venous thrombus in patients on anticoagulation with heparin and vitamin K inhibitors. This remodeling involves the complex process of adhesion of thrombus to the wall of the vein, the inflammatory response of the vessel wall leading to organization and subsequent contraction of the thrombus, neovascularization and spontaneous lysis of areas within the thrombus. The occurrence of spontaneous arterial flow in recanalized thrombosed veins has been described as secondary to neovascularization and is characterized by the development of flow patterns characteristic of arteriovenous fistulae that can be identified by color duplex scanning. In this review, we discuss some controversial aspects of the natural history of deep vein thrombosis to provide a better understanding of its course and its impact on venous disease.

Natural history of deep vein thrombosis in children

2014 ◽  
Vol 30 (6) ◽  
pp. 412-417 ◽  
Author(s):  
G Spentzouris ◽  
A Gasparis ◽  
RJ Scriven ◽  
TK Lee ◽  
N Labropoulos
Keyword(s):  
Deep Vein Thrombosis ◽  
Signs And Symptoms ◽  
Chronic Venous Disease ◽  
Venous Disease ◽  
Vein Thrombosis ◽  
History Of ◽  
Recurrent Deep Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Objective To determine the natural history of deep vein thrombosis in children presented with a first episode in the lower extremity veins. Methods Children with objective diagnosis of acute deep vein thrombosis were followed up with ultrasound and clinical examination. Risk factors and clinical presentation were prospectively collected. The prevalence of recurrent deep vein thrombosis and the development of signs and symptoms of chronic venous disease were recorded. Results There were 27 children, 15 males and 12 females, with acute deep vein thrombosis, with a mean age of 4 years, range 0.1–16 years. The median follow-up was 23 months, range 8–62 months. The location of thrombosis involved the iliac and common femoral vein in 18 patients and the femoral and popliteal veins in 9. Only one vein was affected in 7 children, two veins in 14 and more than two veins in 6. Recurrent deep vein thrombosis occurred in two patients, while no patient had a clinically significant pulmonary embolism. Signs and symptoms of chronic venous disease were present at last follow-up in 11 patients. There were nine patients with vein collaterals, but no patient developed varicose veins. Reflux was found in 18 veins of 11 patients. Failure of recanalization was seen in 7 patients and partial recanalization in 11. Iliofemoral thrombosis ( p = 0.012) and failure to recanalize ( p = 0.036) increased significantly the risk for developing signs and symptoms. Conclusions Children with acute proximal deep vein thrombosis develop mild chronic venous disease signs and symptoms at mid-term follow-up and are closely related with iliofemoral thrombosis and failure to recanalization.

scholarly journals Prediction of Long-term Results of Conservative Treatment of Acute Deep Vein Thrombosis of Lower Limbs

2019 ◽  
Vol 58 (6) ◽  
pp. e518-e519
Author(s):  
Kirill N. Fomin ◽  
V.V. Soroka ◽  
S.P. Nohrin ◽  
A.B. Kurilov ◽  
Belousov E. Yu ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Conservative Treatment ◽  
Lower Limbs ◽  
Long Term Results ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

A Prognostic Score to Identify Low-risk Outpatients with Acute Deep Vein Thrombosis in the Lower Limbs

2015 ◽  
Vol 128 (1) ◽  
pp. 90.e9-90.e15 ◽  
Author(s):  
Javier Trujillo-Santos ◽  
Francisco Lozano ◽  
Manuel Alejandro Lorente ◽  
Dolores Adarraga ◽  
Jana Hirmerova ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Prognostic Score ◽  
Low Risk ◽  
Lower Limbs ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

scholarly journals Features of etiology and pathogenesis of acute deep vein thrombosis in children of different age groups. Results of a prospective cohort study in parallel groups

2019 ◽  
Vol 100 (3) ◽  
pp. 410-415
Author(s):  
I N Nurmeev ◽  
L M Mirolubov ◽  
L I Batyrshina ◽  
N N Nurmeev ◽  
M R Gilmutdinov ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Age Groups ◽  
First Year ◽  
Predisposing Factor ◽  
Vein Thrombosis ◽  
Venous Catheterization ◽  
History Of ◽  
Acute Deep Vein Thrombosis ◽  
First Year Of Life ◽  
Deep Vein

Aim. To study the characteristics of the etiology and clinical picture of acute deep vein thrombosis in children of different age groups. Methods. The article analyzes the diagnosis and treatment of 77 children and adolescents with acute deep vein thrombosis. The features of the history of patients, previous fact of deep venous catheterization were studied. The fact of the presence and absence of clinical symptoms of thrombosis is registered. The results of ultrasound diagnostics are used. All patients underwent a course of anticoagulant therapy. The results of diagnosis and treatment were evaluated taking into account the age of the patients, the presence/absence of the history of catheterization of deep veins. Results. When comparing different age groups, their distinctive characteristics were revealed: predominant presence of asymptomatic catheter-associated thrombosis in the younger age group (newborns and infants) with symptomatic deep vein thrombosis of various origin in older children. Among the surveyed, the majority (75.3%) had asymptomatic thrombosis. Pain (2.6%), edema (3.9%) and a combination of pain and edema (18.2%) were more common among symptomatic patients with the symptoms of acute vein thrombosis. In some cases, a combination of two or more complaints was noted. Asymptomatic thrombosis in the catheter-associated thrombosis group amounted to 96.6%. All patients below 1 year had a predisposing factor in the history: 95% - preceding vein catheterization, 5% - postoperative period. With a history of venous catheterization, symptoms of thrombosis were detected 9.2 times less frequently than in children without vein catheterization. In the group of children older than a year, the ratio of thrombosis without a predisposing factor was 10.5%, and the ratio of children with symptoms of thrombosis was 1.38 times higher than among children younger than a year. The only fatal outcome: a 17-year-old patient with a history of thrombophilia, thrombosis of the left iliac vein, pulmonary embolism. Conclusion. Deep vein thrombosis in children of the first year of life in all cases was caused by a predisposing factor: in children during the first year of life in 95% of cases deep vein thrombosis was asymptomatic and was revealed by ultrasound examination.

scholarly journals Surviving Complications of Retroperitoneal Fibrosis with Intermittent Relapses over a Period of 20 years: Case report and literature Review

2021 ◽  
pp. 1-18
Author(s):  
Sunita Dinkar ◽  
Srajan Dashore ◽  
Sunil Joshi ◽  
Himanshu Shah ◽  
Tushar Shah
Keyword(s):  
Deep Vein Thrombosis ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Retroperitoneal Fibrosis ◽  
Vena Cava ◽  
Lower Limbs ◽  
Idiopathic Retroperitoneal Fibrosis ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Idiopathic retroperitoneal fibrosis is a rare fibro-inflammatory disease of varied etiology which usually originates around aorta and spreads caudally along Iliac vessels into adjacent retroperitoneum causing ureteral obstruction as the most frequent complication. A 53-year-old male patient presented with complaint of mild pain in both the legs off and on. On investigating further, we found that he had been struggling with intermittent relapses every 3-4 years for last 20 years since he was first diagnosed with Idiopathic Retroperitoneal Fibrosis. He was 33-year-old when he first developed the symptoms of anuria for 48 hours and was diagnosed with Idiopathic retroperitoneal fibrosis. This was followed by atrophy of left kidney and hypertension 6 years later, then hypothyroidism after another 3years and finally involvement of Inferior Vena Cava and acute Deep Vein Thrombosis of lower limbs after another 3-4 years. His deep vein thrombosis was well managed in time. He was put on glucocorticoids everytime he had a relapse and a complication. We did a review of literature to understand recent advances about its pathogenesis, diagnosis, investigations and management. We searched in PubMed using terms like retroperitoneal fibrosis alone and in combination with related terms such as Inferior Vena Cava thrombosis, Deep Vein Thrombosis, Tamoxifen, Methotrexate. This case is unique as it is very rare to find acute Deep Vein Thrombosis in Idiopathic retroperitoneal fibrosis without development of any collaterals when Inferior Vena Cava lumen is compromised to almost complete obstruction. After a follow up of 20 years patient is doing well in terms of physical activity and psychological wellbeing with anti-hypertensives, thyroxine and anti-coagulants. Is the disease-free interval actually free of the disease or it just subsided with immunosuppressants to become active after some time?

scholarly journals Comparison of a Pocket-Sized Versus a Full-Sized Ultrasound System in the Diagnosis of Proximal Lower Limb Acute Deep Vein Thrombosis

2018 ◽  
Vol 34 (4) ◽  
pp. 245-251
Author(s):  
Hang Yee Lau ◽  
Wing Hang Luk ◽  
Dilys Choi Yu Lui ◽  
Eliza Po Yan Fung
Keyword(s):  
Deep Vein Thrombosis ◽  
Lower Limb ◽  
Lower Limbs ◽  
Vein Thrombosis ◽  
Comparable Performance ◽  
Acute Deep Vein Thrombosis ◽  
Ultrasound System ◽  
Sensitivity Specificity ◽  
Deep Vein ◽  
Proximal Lower Limb

This study assessed the performance of a pocket-sized ultrasound system for the diagnosis of proximal lower limb acute deep vein thrombosis (DVT) compared to a full-sized ultrasound system. Patients who needed urgent lower limb sonograms for acute DVT were invited for the study. In each examination, the investigator scanned the patient using the pocket-sized system and then repeated the scan using the full-sized system. The sensitivity, specificity, and accuracy of the pocket-sized system were determined in reference to the full-sized system. The venous segments that failed to be visualized using the two systems were compared. One hundred lower limbs comprising 500 venous segments were examined. There were four venous segments, including two mid and two lower femoral veins in two patients who failed to be visualized using both systems. The sensitivity, specificity, and accuracy for diagnosing proximal lower limb acute DVT were 100% (95% confidence interval [CI], 94.94%–100%), 100% (95% CI, 99.05%–100%), and 100% (95% CI, 99.19%–100%), respectively. The pocket-sized ultrasound system and the full sized-ultrasound system demonstrated a comparable performance in detecting acute DVT in the leg.

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