scholarly journals Assessment of the Relationship Between Matrix Metalloproteinase-9 Promoter Gene Polymorphism and Chronic Periodontitis

2021 ◽  
Vol 21 ◽  
Author(s):  
Hiroj Bagde ◽  
Savitha Banakar ◽  
Alka Waghmare ◽  
Ashwini Bagde ◽  
Shailendra Singh Chaturvedi ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Chronic Periodontitis ◽  
Matrix Metalloproteinase 9 ◽  
Promoter Gene ◽  
The Relationship ◽  
Metalloproteinase 9

Association of Matrix Metalloproteinase-9 Promoter Gene Polymorphism With Chronic Periodontitis

2006 ◽  
Vol 77 (9) ◽  
pp. 1510-1514 ◽  
Author(s):  
Gonca Cayir Keles ◽  
Sezgin Gunes ◽  
A. Pinar Sumer ◽  
Mahmut Sumer ◽  
Nurten Kara ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Chronic Periodontitis ◽  
Matrix Metalloproteinase 9 ◽  
Promoter Gene ◽  
Metalloproteinase 9

Matrix metalloproteinase-9 promoter gene polymorphism (−1562C>T) in nasal polyposis

2009 ◽  
Vol 23 (6) ◽  
pp. 568-570 ◽  
Author(s):  
Selim S. Erbek ◽  
Erkan Yurtcu ◽  
Seyra Erbek ◽  
Feride I. Sahin
Keyword(s):  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Nasal Polyposis ◽  
Matrix Metalloproteinase 9 ◽  
Promoter Gene ◽  
Metalloproteinase 9

Alliance of matrix metalloproteinase-9 (MMP-9) promoter gene polymorphism with chronic and aggressive periodontitis in Indian population

Meta Gene ◽  
2017 ◽  
Vol 12 ◽  
pp. 88-93 ◽  
Author(s):  
Poulami Majumder ◽  
Sangh Jyoti Singh ◽  
Vineet Nair ◽  
Pranami Bhaumik ◽  
Ashutosh Mukherjee ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Indian Population ◽  
Aggressive Periodontitis ◽  
Matrix Metalloproteinase 9 ◽  
Promoter Gene ◽  
Metalloproteinase 9

Lack of association of matrix metalloproteinase-9 promoter gene polymorphism in obstructive sleep apnea syndrome

2015 ◽  
Vol 43 (7) ◽  
pp. 1099-1103 ◽  
Author(s):  
Mustafa Yalcınkaya ◽  
Selim S. Erbek ◽  
Seda Turkoglu Babakurban ◽  
Elif Kupeli ◽  
Serife Bozbas ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Promoter Gene ◽  
Apnea Syndrome ◽  
Metalloproteinase 9

Matrix metalloproteinase-9 −1562 C/T gene polymorphism in Serbian patients with multiple sclerosis

2007 ◽  
Vol 189 (1-2) ◽  
pp. 147-150 ◽  
Author(s):  
M ZIVKOVIC ◽  
T DJURIC ◽  
E DINCIC ◽  
R RAICEVIC ◽  
D ALAVANTIC ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Matrix Metalloproteinase 9 ◽  
Metalloproteinase 9

scholarly journals Matrix metalloproteinase-9 -1562 C/T polymorphism is associated with the risk of sepsis in a Chinese population: A retrospective study

2021 ◽  
pp. 175342592199241
Author(s):  
Cuijuan Zheng ◽  
Jiayu Wang ◽  
Shouxiang Xie
Keyword(s):  
Matrix Metalloproteinase ◽  
Chinese Population ◽  
Fragment Length Polymorphism ◽  
Diagnostic Marker ◽  
Serum Levels ◽  
Matrix Metalloproteinase 9 ◽  
Han Chinese ◽  
Sepsis Risk ◽  
The Relationship ◽  
Metalloproteinase 9

Matrix metalloproteinase-9 (MMP-9) has been shown to participate in the pathogenesis of sepsis. In this study, we recruited 312 sepsis patients and 413 controls to explore the relationship between sepsis risk and the MMP-9 -1562 C/T polymorphism in Han Chinese. The PCR restriction fragment length polymorphism method was used for genotyping. Our data indicated that the MMP-9 -1562 C/T polymorphism was related with the risk of sepsis (CT vs. CC: P = 0.033, odds ratio (OR) = 1.45, 95% confidence interval (CI) 1.03–2.05; TT+CT vs. CC: P = 0.019, OR = 1.49, 95% CI 1.07–2.07). Stratified analyses demonstrated that this effect was more evident in smokers, drinkers, females and overweight individuals. Furthermore, cross-over analyses suggested that the combined effect of smoking and CT genotype of -1562 C/T polymorphism contributed to the risk of sepsis. In addition, MMP-9 serum levels were significantly lower in sepsis patients than in controls. The MMP-9 -1562 C/T polymorphism was significantly associated with decreased MMP-9 serum levels. Lastly, we observed that this polymorphism was connected to the mortality of sepsis. In conclusion, the interaction between the MMP-9 -1562 C/T polymorphism and smoking correlated with the risk of sepsis in Han Chinese. This polymorphism may serve as a diagnostic marker for sepsis patients.

scholarly journals Matrix metalloproteinase-9 gene polymorphism (-1562 C/T) and its correlation with diabetic nephropathy

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Kholoud Shalaby ◽  
Rania Bahriz ◽  
Nancy Mahsoub ◽  
Mohammed M. El-Arman ◽  
Ghada El-Said
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Gene Polymorphism ◽  
Matrix Metalloproteinase ◽  
Microvascular Complications ◽  
Matrix Metalloproteinase 9 ◽  
Metalloproteinase 9

Abstract Background Matrix metalloproteinase 9 (MMP-9) is an important inflammatory marker in diabetic nephropathy. Many studies assessed the association between MMP-9 gene polymorphism and different microvascular complications of type 2 diabetes mellitus, though the results were inconclusive and need further exploration. Our study aimed to assess the association between MMP-9 -1562C/T gene polymorphism and diabetic nephropathy in patients with type 2 diabetes mellitus. Results Taking CC genotype of rs3918242 (MMP-9-1562C/T SNP) as the reference genotype and C as the reference allele, TT genotype, T allele showed significantly lower frequency in diabetic nephropathy group than without nephropathy (2.9% versus 20%, 20% versus 35.7% respectively), with the possible significant protective effect against diabetic nephropathy development (OR = 0.269, 0.450 respectively); it was considered as an independent predictor for diabetic nephropathy occurrence. Conclusions This study suggested that T allele of MMP-9 -1562C/T single nucleotide polymorphism had a protective role against diabetic nephropathy development and also had a role for early prediction of patients susceptible to this complication, so it helps in prevention and management of those patients.

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