INTERMEDIATE ENDEMICITY OF HEPATITIS A VIRUS INFECTION IN RURAL SETTLEMENT PROJECTS OF SOUTHWEST GOIÁS, BRAZIL

BackgroundRural populations present an elevated risk of exposure to hepatitis A virus.ObjectiveThe objective of this study was to estimate the prevalence and risk factors associated with hepatitis A virus infection among residents of rural settlement projects of southwest Goiás, Central Brazil.MethodsA total of 466 residents were interviewed and tested for the detection of anti- hepatitis A virus antibodies by ELISA.ResultsThe global prevalence of anti- hepatitis A virus was 82.2%. In individuals aged 5-9 years and 10-19 years, the prevalence was 15% and 58.8%, respectively. Persons in the 10-19 age group, with a history of life in encampments, with more than five people per residence consuming well water, were predictors for exposure to hepatitis A virus.ConclusionOur results suggest that the hepatitis A virus endemicity in rural settlements in southwest Goiás similar to that found in the urban population of the Midwest Region, confirming the implementation of universal hepatitis A vaccination in children.

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Clinical Factors Associated with Hepatitis A Virus Seropositivity in HIV-Infected Adults Living in a Country with an Epidemiologic Shift for Hepatitis A Virus Infection

Journal of Korean Medical Science ◽

10.3346/jkms.2012.27.8.969 ◽

2012 ◽

Vol 27 (8) ◽

pp. 969 ◽

Cited By ~ 4

Author(s):

Ji Hyeon Baek ◽

Chang Oh Kim ◽

Jun Yong Park ◽

Su Jin Jeong ◽

Nam Soo Koo ◽

...

Keyword(s):

Virus Infection ◽

Hepatitis A ◽

Hepatitis A Virus ◽

Clinical Factors ◽

Factors Associated

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Positive Test Results for Acute Hepatitis A Virus Infection Among Persons With No Recent History of Acute Hepatitis--United States, 2002-2004

JAMA ◽

10.1001/jama.294.8.894 ◽

2005 ◽

Vol 294 (8) ◽

pp. 894-896

Keyword(s):

United States ◽

Virus Infection ◽

Acute Hepatitis ◽

Hepatitis A ◽

Hepatitis A Virus ◽

Positive Test ◽

Recent History ◽

Test Results ◽

Acute Hepatitis A ◽

History Of

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Prevalence of hepatitis A virus infection: the paradoxical example of isolated communities in the western Brazilian Amazon region

Revista da Sociedade Brasileira de Medicina Tropical ◽

10.1590/s0037-86822009000300008 ◽

2009 ◽

Vol 42 (3) ◽

pp. 277-281 ◽

Cited By ~ 8

Author(s):

Wornei Silva Miranda Braga ◽

Fabiane Giovanella Borges ◽

Gildo Maia Barros Júnior ◽

Ana Cristina de Souza Martinho ◽

Ivo Seixas Rodrigues ◽

...

Keyword(s):

Virus Infection ◽

Hepatitis A ◽

Hepatitis A Virus ◽

Linear Trend ◽

Univariate Analysis ◽

Brazilian Amazon ◽

Amazon Region ◽

Serum Samples ◽

Brazilian Amazon Region ◽

History Of

This study evaluated the prevalence of hepatitis A virus infection in the rural area of Lábrea, in the western Brazilian Amazon region. Communities and households were selected randomly. Serum samples were analyzed by means of the immunoenzymatic method for the presence of total antibodies against HAV. The study included 1,499 individuals. The prevalence of anti-HAV was 74.6% (95% CI 72.3-76.8). Univariate analysis showed associations with age (chi-square for linear trend = 496.003, p < 0.001), presence of outside toilet (p < 0.001), history of hepatitis (p < 0.001) and family history of hepatitis (p = 0.05). After adjusting for age, HAV infection also showed an association with the number of people in the family (p = 0.03). The overall prevalence rates were high, but not more than 60% of the children under the age of ten years had already been infected. Very high prevalence was detected only within older cohorts, thus paradoxically defining this as a region with intermediate endemicity, even under the conditions of poverty encountered.

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