scholarly journals Hypertrophic pachymeningitis: case report

2003 ◽  
Vol 61 (1) ◽  
pp. 107-111 ◽  
Author(s):  
Leonardo de Deus-Silva ◽  
Luciano de Souza Queiroz ◽  
Verônica de Araújo Zanardi ◽  
Enrico Ghizoni ◽  
Hoyama da Costa Pereira ◽  
...  
Keyword(s):  
Case Report ◽  
Optic Atrophy ◽  
Nasal Septum ◽  
Visual Loss ◽  
Inflammatory Process ◽  
Inflammatory Diseases ◽  
Early Stage ◽  
Underlying Disease ◽  
Extensive Investigation ◽  
Hypertrophic Pachymeningitis

Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.

scholarly journals Bilateral Optic Atrophy with Thickened Meninges (Idiopathic Hypertrophic Pachymeningitis) - A Rare Entity

JMS SKIMS ◽  
2011 ◽  
Vol 14 (1) ◽  
pp. 25-27
Author(s):  
Ravouf Asmi ◽  
Feroze Ahmad ◽  
Rangreze Imran ◽  
Zarka Amin Masoodi ◽  
Mushtaq A Wani
Keyword(s):  
Infectious Diseases ◽  
Optic Atrophy ◽  
Visual Loss ◽  
Unknown Etiology ◽  
Inflammatory Disorder ◽  
Rare Entity ◽  
Hypertrophic Pachymeningitis ◽  
Open Biopsy

Idiopathic hypertrophic pachymeningitis (IHP) is a rare, chronic nonspecific and granulomatous inflammatory disorder of the dura with unknown etiology. The diagnosis can be established by an open biopsy and exclusion of all other specific granulomatous and infectious diseases. We report a case of Idiopathic hypertrophic pachymeningitis who manifested primarily by headache and visual loss with optic atrophy. The patient was thoroughly investigated and showed no evidence of underlying cause. The diagnosis was established by an open biopsy. JMS 2011;14(1):25-27

scholarly journals Idiopathic Hypertrophic Pachymeningitis: A Case Report from Bangladesh

2018 ◽  
Vol 3 (2) ◽  
pp. 110-112
Author(s):  
Meera Momtaz Sabeka ◽  
Md Nazrul Islam
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Optic Atrophy ◽  
Severe Headache ◽  
Imaging Studies ◽  
Hypertrophic Pachymeningitis ◽  
History Of ◽  
Diagnostic Clue ◽  
Work Up ◽  
Rule Out

A 52 years old lady presented with sudden severe headache with the history of similar intense headache twenty years back which ended up with left sided blindness. Her physical examination was unremarkable except optic atrophy of the left eye. Investigation included biochemical work up, imaging studies and CSF study. The MRI of brain with contrast gave the key diagnostic clue with characteristic findings of hypertrophic pachymeningitis. Other investigations helped to rule out possible etiologies and the diagnosis idiopathic hypertrophic pachymeningitis was finally made. The patient has been treated with steroid and enjoyed improvement in her yearlong symptoms.Journal of National Institute of Neurosciences Bangladesh, 2017;3(2): 110-112

scholarly journals Huge hard palate and nasal septum perforation as a presentation of syphilis: A case report

2012 ◽  
Vol 11 (3) ◽  
pp. 234-237
Author(s):  
B Shahrjerdi ◽  
I Mohamad
Keyword(s):  
Case Report ◽  
Nasal Septum ◽  
Hard Palate ◽  
Medical Science ◽  
Underlying Disease ◽  
Septal Perforation ◽  
Diagnostic Challenge ◽  
Septum Perforation ◽  
Nasal Septum Perforation ◽  
Septal Perforations

A patient presented with septal and palatal perforations imposes a diagnostic challenge because various potential causes need to be established. Therefore, elucidating the cause of the septal perforation requires obtaining a thorough history. In addition, it is very important to perform necessary investigations for the patients to determine and fix the underlying disease which cause these complaints. We report a case of patient presented with palatal and septal perforations which later was confirmed to have syphilis. DOI: http://dx.doi.org/10.3329/bjms.v11i3.11737 Bangladesh Journal of Medical Science Vol. 11 No. 03 July’12

scholarly journals Recurrent ominous spinal mass

2019 ◽  
Vol 5 (3) ◽  
pp. 75
Author(s):  
Maria Gollwitzer ◽  
Wolfgang Hasenauer ◽  
Anja Grimmer ◽  
Andreas Gruber
Keyword(s):  
Patient Management ◽  
Inflammatory Process ◽  
Low Dose ◽  
Recurrent Disease ◽  
Underlying Disease ◽  
Acute Onset ◽  
Hypertrophic Pachymeningitis ◽  
Rare Form ◽  
Acute Patient ◽  
Spinal Mri

<p class="abstract">Hypertrophic pachymeningitis is a very rare form of diffuse inflammatory dural fibrosis. It is typically encountered intracranially rather than spinally and can have a progressive and recurrent course as encountered in our patient. The aetiology of this disorder is multifactorial. While acute management of hypertrophic pachymeningitis consists of immediate decompression in conjunction with steroid medication and treatment of the underlying disease, the management of chronic and recurrent disease is controversially debated in the current literature. A previously healthy 49-year-old woman presented with progressive back pain and acute onset of incomplete paraplegia. Spinal MRI showed a large ventral semicircular mass with intense contrast enhancement from Th3-8. Acute patient management consisted of immediate decompression and debulking the space-occupying lesion in conjunction with antibiotic and steroid therapy. Histopathologic examination of the surgical specimens revealed a chronic inflammatory process. The patient fortunately recovered from the severe paraparesis and upon discharged, spinal MRI disclosed a further regressing residual spinal mass. Over time, our patient suffered two times a relapse and was finally treated with Methotrexate and low-dose steroids. Under this medication she has made a nearly complete neurological recovery. This case report highlights a rare disease with challenging management, which should be considered diagnostically in patients with intraspinal space-occupying lesions. In our experience combination of Methotrexate and low-dose steroids might be an effective and safe treatment.</p>

scholarly journals A Case of Hypertrophic Pachymeningitis Associated with Immunoglobulin-G4 and c-ANCA

2019 ◽  
Vol 11 (3) ◽  
pp. 290-294 ◽  
Author(s):  
Stephanie Wyrostek ◽  
Satabdi Chakrabarti ◽  
Kelly Baldwin ◽  
J. David Avila
Keyword(s):  
Case Report ◽  
Dura Mater ◽  
Granulomatosis With Polyangiitis ◽  
Inflammatory Diseases ◽  
Antineutrophil Cytoplasmic Antibodies ◽  
Hypertrophic Pachymeningitis ◽  
Immunoglobulin G4 ◽  
Related Disease ◽  
Igg4 Related Disease ◽  
Systemic Manifestations

Hypertrophic pachymeningitis (HP) is characterized by inflammation of the dura mater. It has been described in the setting of numerous systemic inflammatory diseases including immunoglobulin G4 (IgG4)-related disease as well as granulomatosis with polyangiitis (GPA). In this case report, we describe a 48-year-old man presenting with headache who was found to have HP and had systemic features of both GPA and IgG4-related disease as well as seropositivity for both cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) and IgG4. He was treated with prednisone and rituximab with improvement in his symptoms. Co-occurrence of IgG4 and ANCA against myeloperoxidase has been reported in other cases of HP. The overlap between IgG4 and ANCA has also been described in other systemic manifestations of the diseases. These reports suggest a clinical overlap between ANCA and IgG4-related disease, and the case presented herein suggests an overlap between GPA and IgG4-related disease.

Pleomorphic Adenoma of the Nasal Septum: A Case Report

Skull Base ◽  
2009 ◽  
Vol 19 (S 02) ◽  
Author(s):  
A. Koutis ◽  
M. Ioannou ◽  
A. Saratziotis ◽  
E. Theos ◽  
H. Gouveris
Keyword(s):  
Case Report ◽  
Pleomorphic Adenoma ◽  
Nasal Septum

scholarly journals Long-term survival with multiple metastasectomies for pulmonary osteosarcoma: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Satoshi Takamori ◽  
Hiroyuki Oizumi ◽  
Jun Suzuki ◽  
Katsuyuki Suzuki
Keyword(s):  
Case Report ◽  
Pulmonary Metastases ◽  
Multidisciplinary Treatment ◽  
Underlying Disease ◽  
Pulmonary Metastasectomy ◽  
Extensive Resection ◽  
Term Survival ◽  
Long Term Survival ◽  
Primary Surgery

Abstract Background Repeat pulmonary metastasectomy (PM) considerably improves the prognosis of patients with pulmonary metastases of osteosarcoma. Reports have demonstrated a significantly improved prognosis in patients who have undergone repeat metastasectomy for osteosarcoma; however, there have been no reports with more than six metastasectomies. Herein, we describe the long-term survival of a patient following resection of multiple tumors and other treatments for metastatic osteosarcoma. Case presentation A 28-year-old woman underwent extensive resection and postoperative adjuvant chemotherapy for right tibial sarcoma. Over the years, she developed repeated pulmonary metastases. First, 116 metastases were removed from the bilateral lungs. After that, multiple PMs of approximately 250 tumors and other treatments for deep metastatic lesions were performed. The patient died of the underlying disease 24 years after the primary surgery. Conclusions This case report demonstrates the long-term survival benefit of a multidisciplinary treatment centered on multiple metastasectomies.

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