scholarly journals The value of necropsy in quality control of medical diagnosis: the gold standard for years to come

Clinics ◽  
2009 ◽  
Vol 64 (3) ◽  
Author(s):  
Paulo Sampaio Gutierrez ◽  
Thales de Brito ◽  
Maria Beatriz Sampaio Lopes ◽  
Venancio Avancini Ferreira Alves
Keyword(s):  
Quality Control ◽  
Gold Standard ◽  
Medical Diagnosis ◽  
To Come

scholarly journals A correlation of hysterolaparoscopic findings and BACTEC culture in infertility

2017 ◽  
Vol 6 (4) ◽  
pp. 1430 ◽  
Author(s):  
Mahesweta Guru ◽  
Prasad Yeshwant Deshmukh
Keyword(s):  
Health Problem ◽  
Gold Standard ◽  
Semen Analysis ◽  
Age Group ◽  
Genital Tuberculosis ◽  
Infertile Women ◽  
Dilatation And Curettage ◽  
Important Health ◽  
To Come ◽  
Sensitive Method

Background: Infertility is agonising condition. Tuberculosis is an important health problem worldwide. One third of the world’s population is currently affected with tuberculosis. Hysterolaparoscopy is a well-recognized procedure for the diagnosis of infertility. Culture for TB bacilli is the gold standard for diagnosis of genital TB.Methods: Infertile women undergoing dilatation and curettage with hysterolaparoscopy with normal husband semen analysis as a part of their infertility workup at M. G. M. Medical Hospital, Kalamboli. Sample size: 30.Results: Incidence of GTB=22.85%, 25-29 year followed by 35-40 years’ age group was the most common age group was observed. In our study, 74.3% infertility pattern was primary, 25.7% were secondary only 2.85 % (n =1) of the cases of GTB were diagnosed by using TB BACTEC. Laparoscopic findings su0ggested that 18 cases had normal findings and 8 cases had laparoscopic features suggestive of GTB. On chromo pertubation, delayed and absent spillage of the dye was seen in 2 cases. On Hysteroscopy, 29 cases (82.9%) of the patients had normal findings and 3 cases had Hysteroscopic features suggestive of GTB.Conclusions: Genital tuberculosis remains an important under diagnosed cause of infertility. Though culture is considered as gold standard for diagnosis of genital tuberculosis, since GTB is paucibacillary there is an urgent need for more research to come to conclusion whether culture is still gold standard. Further research is required to detect the most sensitive method for diagnosis.

scholarly journals A SYSTEMATIC REVIEW OF MODIFICATIONS IN PREPARATION OF KSHARASUTRA AND ITS APPLICATION TECHNIQUES IN PATIENTS OF BHAGANDARA (FISTULA-IN-ANO)

2020 ◽  
pp. 1-4
Author(s):  
Supriya Gupta ◽  
B. Kothainayagi ◽  
Avnish Pathak
Keyword(s):  
Systematic Review ◽  
Gold Standard ◽  
Economic Status ◽  
Fistula In Ano ◽  
Socio Economic Status ◽  
Application Techniques ◽  
Challenging Technique ◽  
Promising Treatment ◽  
To Come ◽  
Complex Cases

Bhagandara (Fistula-in-ano) is well known cause of morbidity in all ages, gender and socio-economic status which has a promising treatment available with Ayurvedic practice of Ksharasutra (medicated setons). This is proven to have relatively lower rates of complications and recurrences. The standardised form of Apamarg Ksharasutra (Snuhi, Apamarg and Haridra churan) is been used for long and still considered the gold standard. However, difficulty in procurement, non-perennial availability of few of its constituents and challenging technique especially in complex cases has always encouraged the practitioners and researchers to come up with trial of other ingredients as per old literature like Sushruta Samhita and to modify the application techniques. This is an endeavour to venture into literature and compile such promising efforts.

Malleability of Meta-Analysis

2018 ◽  
Author(s):  
Jacob Stegenga
Keyword(s):  
Systematic Reviews ◽  
Gold Standard ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Medical Science ◽  
Ongoing Debate ◽  
Medical Interventions ◽  
Reliable Source ◽  
To Come ◽  
Meta Analyses

An astonishing volume and diversity of evidence is available for many hypotheses in medicine. Some of this evidence—usually from randomized trials—is amalgamated by meta-analysis. Despite the ongoing debate regarding whether or not randomized trials are the gold standard of evidence, the most reliable source of evidence in medical science is usually thought to come from systematic reviews and meta-analyses. This chapter argues that meta-analyses are malleable. Different meta-analyses of the same evidence can reach contradictory conclusions. Meta-analysis fails to provide objective grounds for assessing the effectiveness and harms of medical interventions because numerous decisions must be made when performing a meta-analysis, which allow wide latitude for subjective idiosyncrasies to influence its outcome.

Surface Plasmon Biosensor Platform for Food Industry

2019 ◽  
Vol 891 ◽  
pp. 103-108
Author(s):  
Suejit Pechprasarn ◽  
Kodchakorn Ittipornnuson ◽  
Thitika Jungpanich ◽  
Nattha Pensupa ◽  
Naphat Albutt
Keyword(s):  
Quality Control ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Gold Standard ◽  
Food Industry ◽  
Life Science ◽  
Screening Methods ◽  
Control Cost ◽  
Food Quality Control

Surface plasmon resonance (SPR) based biosensor is a gold standard optical sensor for biological protein interaction in life science. In this paper, we firstly discuss how the SPR based sensor can give unique advantages over other sensing techniques for food safety and food quality control in food industry. We discuss the differences in sample preparation process for the SPR system and other screening methods and point out that the SPR can reduce the food screen quality control cost and time. A brief review of food analysis that has been tested under SPR system. Key requirements for building up a surface plasmon resonance based sensor for food industry especially in Thailand are highlighted. An SPR based sensor has been recently developed and constructed based on the requirements. We also discuss practical issues and how to possibly get around them.

Caveat Computator

1967 ◽  
Vol 6 (03) ◽  
pp. 127-130
Author(s):  
J. F. Kuhtzke
Keyword(s):  
Multiple Sclerosis ◽  
Quality Control ◽  
Medical Research ◽  
Medical Diagnosis ◽  
Signs And Symptoms ◽  
Black Box ◽  
The Body ◽  
Data Handling ◽  
Input And Output ◽  
Medical Reports

Electronic data processing by computers is playing an increasing role in medicine as elsewhere in our society. The use of computers in medical research too often leads to the presentation of conclusions impossible to substantiate from the text. Computers require even more attention to research design and »quality control« of data-handling than non-electronic measures, since the basic data are often too massive for presentation, and the »black box« nature of the computer effectively hides the transitions between input and output. Electronic retrieval of data from narrative medical reports appears to be unfeasible in any routine setting, and medical diagnosis by computer appears totally impractical: as exemplified in multiple sclerosis, the responses of the body to varied noxae are too limited to provide sufficiently discriminatory signs and symptoms or patterns of same to permit computer appraisal.

scholarly journals The Next Million Names for Archaea and Bacteria

2020 ◽  
Author(s):  
Mark J. Pallen ◽  
Andrea Telatin ◽  
Aharon Oren
Keyword(s):  
Eighteenth Century ◽  
Quality Control ◽  
Unmet Need ◽  
Microbial Genomics ◽  
Microbial World ◽  
Road Map ◽  
To Come ◽  
Proof Of Principle

Latin binomials, popularised in the eighteenth century by the Swedish naturalist Linnaeus, have stood the test of time in providing a stable, clear and memorable system of nomenclature across biology. However, relentless and ever-deeper exploration and analysis of the microbial world has created an urgent unmet need for huge numbers of new names for Archaea and Bacteria. Manual creation of such names remains difficult and slow and typically relies on expert-driven nomenclatural quality control. Keen to ensure the legacy of Linnaeus lives on in the age of microbial genomics and metagenomics, we propose an automated approach, employing combinatorial concatenation of roots from Latin and Greek to create linguistically correct names for genera and species that can be used off the shelf as needed. As proof of principle, we document over a million new names for Bacteria and Archaea. We are confident that our approach provides a road map for how to create new names for decades to come.

scholarly journals RESEARCH AND DEVELOPMENT OF QUESTION-ANSWER SYSTEMS FOR THE KAZAKH LANGUAGE

2020 ◽  
Vol 71 (3) ◽  
pp. 255-262
Author(s):  
D.R. Rakhimova ◽  
◽  
U.Z. Kenes ◽  
Keyword(s):  
Quality Control ◽  
Gold Standard ◽  
Hidden Markov ◽  
Problem Analysis ◽  
Systematic Classification ◽  
Rule Based ◽  
Question Analysis ◽  
New Methods ◽  
The Relationship ◽  
Language Question

This study describes and evaluates the methods developed for the module for the analysis of problems of the closed subject system of answers to questions for the Kazakh language. Question analysis is one of the most important components of a quality control system to obtain the information needed to determine what is being asked and how to answer it. Therefore, we propose new methods of problem analysis in two main problems, namely rule-based and hidden Markov model based on the integration of systematic classification, focus extraction and question classifiers, both of which depend on the relationship between words in the problem. uses the ratio. It also compares these solutions with basic models. This study also manually presents the gold standard aggregated and annotated data for further research in this area.

scholarly journals Evaluation of Viasure SARS-CoV-2 RT-qPCR kit (CerTest Biotec) using CDC FDA EUA RT-qPCR kit as a gold standard

2020 ◽  
Author(s):  
Byron Freire-Paspuel ◽  
Patricio Vega-Mariño ◽  
Alberto Velez ◽  
Paulina Castillo ◽  
Marilyn Cruz ◽  
...  
Keyword(s):  
Quality Control ◽  
Gold Standard ◽  
Evaluation Studies ◽  
Rna Extraction ◽  
Rna Quality ◽  
Reliable Tool ◽  
Control Probe ◽  
Rna Quality Control

AbstractBackgroundSeveral RT-qPCR kits are available for SARS-CoV-2 diagnosis, some of them with Emergency Use Authorization (EUA) by FDA, but most of them lacking of proper evaluation studies due to covid19 emergency.ObjectiveWe evaluated Viasure RT-qPCR kit (CerTest Biotec, Spain) for SARS-CoV-2 diagnosis using CDC FDA EUA kit as gold standard.ResultsAlthough we found the lack of RNA quality control probe as the main limitation for Viasure kit, the sensitivity was up to 97.5% and specificity was 100%.ConclusionsViasure RT-qPCR kit is a reliable tool for SARS-CoV-2 diagnosis but improvement of an alternative RT-qPCR reaction for RNA extraction quality control as RNaseP is recommended.

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