scholarly journals Development and characterization of pullulan-polymethacrylate free films as potential material for enteric drug release

2017 ◽  
Vol 53 (3) ◽  
Author(s):  
Isabela Angeli de Lima ◽  
Suelen Plaza Pomin ◽  
Osvaldo Albuquerque Cavalcanti
Keyword(s):  
Drug Release ◽  
Free Films

Characterization of ethylcellulose free films by positron annihilation spectroscopy and mechanical testing

2014 ◽  
Vol 115 ◽  
pp. 47-50 ◽  
Author(s):  
Diána Hegyesi ◽  
Károly Süvegh ◽  
András Kelemen ◽  
Klára Pintye-Hódi ◽  
Géza Regdon
Keyword(s):  
Positron Annihilation ◽  
Mechanical Testing ◽  
Positron Annihilation Spectroscopy ◽  
Free Films

Preparation and characterization of free films of high amylose/pectin mixtures cross-linked with sodium trimetaphosphate

2012 ◽  
Vol 38 (11) ◽  
pp. 1354-1359 ◽  
Author(s):  
Fabíola Garavello Prezotti ◽  
Andréia Bagliotti Meneguin ◽  
Raul Cesar Evangelista ◽  
Beatriz Stringhetti Ferreira Cury
Keyword(s):  
Sodium Trimetaphosphate ◽  
Free Films ◽  
High Amylose

Synthesis and characterization of polyelectrolyte complex microparticles for drug release

2012 ◽  
Vol 128 (6) ◽  
pp. 3548-3554 ◽  
Author(s):  
L. Agüero ◽  
J. García ◽  
O. Valdés ◽  
G. Fuentes ◽  
D. Zaldivar ◽  
...  
Keyword(s):  
Drug Release ◽  
Polyelectrolyte Complex ◽  
Synthesis And Characterization

SYNTHESIS AND CHARACTERIZATION OF THIOLATED GUM KONDAGOGU AND EVALUATION AS MUCOADHESIVE POLYMER

INDIAN DRUGS ◽  
2020 ◽  
Vol 57 (01) ◽  
pp. 37-43
Author(s):  
Ashwin A. Patil ◽  
Ketan B. Patil ◽  
Laxmikant R. Zawar
Keyword(s):  
Drug Release ◽  
Release Kinetics ◽  
Matrix Tablet ◽  
Disintegration Time ◽  
Weight Variation ◽  
Zero Order Release ◽  
Gum Kondagogu ◽  
Ellman’S Method

Present work focused on thiolation for enhancing the mucoadhesive potential of Gum kondagogu (GK). Thiolation of GK was done by esterification process with 80 % thioglycolic acid in presence of 7N HCl. Thiolated Gum kondagogu (ThioGK) was determined to possess 1.59 ±0.04 mmol of thiol groups/g of the polymer by Ellman’s method. ThioGK was characterized by FTIR, NMR, DSC, XRD, and FE-SEM. The tablets were prepared by direct compression using 75 mg of ThioGK and GK. Tablets containing ThioGK (F1) and GK (F2) were subjected to evaluation of weight variation, hardness and friability and show enhanced disintegration time, swelling behavior, drug release and mucoadhesion. In vitro drug release of batch F1 exhibits complete release of drug in 24 hr with zero order release kinetics. Comparative mucoadhesive strength was studied using chicken ileum by texture analyzer and revealed higher mucoadhesion of tablet containing ThioGK. From the above study, ThioGK was suitability exploited as mucoadhesive sustained release matrix tablet.

DESIGN AND CHARACTERIZATION OF ALFUZOSIN HCL GASTRORETENTIVE FLOATING MATRIX TABLETS EMPLOYING HPMC K 100M

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (11) ◽  
pp. 71-73
Author(s):  
Ch. Taraka Ramarao ◽  
◽  
J Vijaya Ratna ◽  
R. B. Srinivasa
Keyword(s):  
Drug Release ◽  
Dosage Forms ◽  
Matrix Tablets ◽  
Fickian Diffusion ◽  
Release Mechanism ◽  
Gastric Residence Time ◽  
Drug Release Mechanism ◽  
The Matrix ◽  
Gastro Retentive

The present investigation involves developing gastro retentive drug delivery systems (GFDDS) of alfuzosin HCl using HPMCK100M a is the matrixing agent and floating enhancer. Sodium bicarbonate in the acidic environment reacts with the acid and produces carbon dioxide. The gastro retentive tablets can be formulated to increase the gastric residence time and thereby increase the oral bioavailability. From the drug release study, it was concluded that the AFTB4 formula of HPMC K 100 M matrix tablets gives the controlled release up to 12 hours by showing increased release with floating lag time 24 seconds. Non – Fickian diffusion was the drug release mechanism from the matrix tablets formulated employing HPMC K 100 M. The matrix tablets (AFTB4) formulated employing 40 % HPMC K 100 M are best suited to be used for gastro retentive dosage form of alfuzosin HCl. Finally, it can be concluded that good candidates for the preparation of gastro retentive dosage forms due its gastric stability, gastric absorption and better bioavailability.

Fabrication and characterization of monodisperse PLGA–alginate core–shell microspheres with monodisperse size and homogeneous shells for controlled drug release

2013 ◽  
Vol 9 (7) ◽  
pp. 7410-7419 ◽  
Author(s):  
Jun Wu ◽  
Tiantian Kong ◽  
Kelvin Wai Kwok Yeung ◽  
Ho Cheung Shum ◽  
Kenneth Man Chee Cheung ◽  
...  
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Core Shell ◽  
Fabrication And Characterization
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