Intracranial Pressure in Single-Suture Craniosynostosis

1998 ◽  
Vol 35 (3) ◽  
pp. 194-196 ◽  
Author(s):  
Steven R. Cohen ◽  
John A. Persing

In this paper, we review the incidence of increased intracranial pressure in children with single-suture craniosynostosis. The major studies in this area are presented, along with their limitations. A rational treatment plan including multidisciplinary team management is recommended. All patients with proven synostosis should be followed closely, whether or not surgery is chosen. Continued clinical and basic science research are necessary to further clarify the ramifications of asymptomatic elevations of intracranial pressure in these patients.

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Yam Nath Paudel ◽  
Efthalia Angelopoulou ◽  
Bhupendra Raj Giri ◽  
Christina Piperi ◽  
Iekhsan Othman ◽  
...  

: COVID-19 has emerged as a devastating pandemic of the century that the current generations have ever experienced. The COVID-19 pandemic has infected more than 12 million people around the globe and 0.5 million people have succumbed to death. Due to the lack of effective vaccines against the COVID-19, several nations throughout the globe has imposed a lock-down as a preventive measure to lower the spread of COVID-19 infection. As a result of lock-down most of the universities and research institutes has witnessed a long pause in basic science research ever. Much has been talked about the long-term impact of COVID-19 in economy, tourism, public health, small and large-scale business of several kind. However, the long-term implication of these research lab shutdown and its impact in the basic science research has not been much focused. Herein, we provide a perspective that portrays a common problem of all the basic science researchers throughout the globe and its long-term consequences.


2021 ◽  
Vol 268 ◽  
pp. 71-78
Author(s):  
Devon Livingston-Rosanoff ◽  
Keon Young Park ◽  
Esra Alagoz ◽  
Susan Thibeault ◽  
Angela Gibson

1998 ◽  
Vol 35 (2) ◽  
pp. 167-172 ◽  
Author(s):  
Roger J. Hudgins ◽  
Steven R. Cohen ◽  
Fernando D. Burstein ◽  
William R. Boydston

Objective Increased intracranial pressure, frequently associated with closure of multiple cranial sutures, has been reported to occur in 36% of cases following correction of syndromal craniosynostosis. Although much less common, multiple suture closure may occur following repair of single suture, non-syndromal craniosynostosis and we present cases that concern two such children. Results Two children with nonsyndromal craniosynostosis, one metopic and one left-coronal, underwent fronto-orbital advancement at age 3 months. At age 19 months and at age 5 years, respectively, both patients re-presented with headaches, decrease in head circumference percentile, and acceptable cosmetic outcome. Both had computerized tomographic evidence of multiple closed cranial sutures and increased intracranial pressure (ICP) (determined by monitoring). Both patients improved following a cranial expansion procedure. Conclusion Delayed closure of multiple sutures and resultant increased ICP may occur following correction of nonsyndromal, single suture craniosynos-tosis. This may be more likely when the initial suture is contiguous with the facial sutures. Children should be followed for many years following cranio-synostosis repair with cranial, neurologic, and possibly funduscopic examinations as well as head circumference measurements to detect delayed closure of cranial sutures.


2021 ◽  
Vol 41 (6) ◽  
pp. 455-462
Author(s):  
Jyotshna Sahoo ◽  
Sudam Charan Sahu ◽  
Basudev Mohanty

The paper’s main objective is to investigate the trends of basic science research in India using a combination of qualitative and quantitative approaches. It examines the publication patterns and impact of research productivity of five basic science institutions, i.e., “Indian Institutes of Science Education and Research” (IISER), namely IISER Kolkata, IISER Pune, IISER Mohali, IISER Bhopal, and IISER Thiruvananthapuram. The research output indexed in the SCOPUS bibliographic database of these five established IISERs was obtained from 2015 to 2019. A total number of 7329 research publications were analysed using various scientometric dimensions. This paper makes a concerted effort to present a comprehensive picture of the assessment of research outcomes at the five older IISERs, which are ostensibly India’s most active and prominent basic science research institutions. The findings reveal that these institutions are accountable for important research outcomes, such as a high number of citations, preferences towards open access (OA) publications, a rise in research publication year over year, a strong author network, a high degree of collaboration, and a high impact in terms of other scientometrics indicators. This paper discusses the findings of the research publications on the position of IISERs in basic sciences research and draws some conclusions about their effects.


2012 ◽  
Vol 8 (3) ◽  
pp. 292-293
Author(s):  
A S Pandey

No abstract availableDOI: http://dx.doi.org/10.3126/kumj.v8i3.6214 Kathmandu Univ Med J 2010;8(3):292-3 


Author(s):  
Derrick C. Wan ◽  
Matthew D. Kwan ◽  
Eric I-Yun Chang ◽  
Geoffrey C. Gurtner ◽  
Michael T. Longaker

Author(s):  
P. Yogeeswari ◽  
D. Sriram

Basic research in Universities is essential for a sustainable development. Recent developments in higher education have seen the inclusion of curiculum redesigned to serve the concept of developming young minds in the intrepretation, execution, and use of basic science research. The challenge for educators is to “demystify” research and teach in ways that are professionally meaningful as well as intellectually acceptable. The objective of this chapter is to bring in various case studies to prove the essentiality of basic research in higher education with specific concern over pharmaceutical industrial growth plans. Data on R&D in higher education can be broken down by field of science (natural sciences, engineering, medical sciences, agricultural sciences, social sciences, and humanities), by type of costs (current expenditures, capital expenditures), and by source of funds (business enterprise, government, higher education, private non-profit, and funds from abroad). Measures of R&D performance in the higher education sector are often estimated by national authorities, and evaluation methods are periodically revised. It is necessary to review the design and conduct of higher education R&D surveys to improve the comparability of these indicators.


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