Influence of Modeling Microgravity Unloading of Hind Limbs on Passive Electric Properties of Thigh-Bone of White Rats

2003 ◽  
Vol 35 (10) ◽  
pp. 38-44
Author(s):  
Oleg M. Levashov ◽  
Sergey L. Saphonov
Keyword(s):  
Electric Properties ◽  
Thigh Bone ◽  
White Rats ◽  
Hind Limbs

scholarly journals AGE-RELATED MORPHOMETRIC CHARACTERISTICS OF REMODELING OF ARTERIAL BED OF HIND LIMBS IN WHITE RATS WITH EXPERIMENTAL HYPERCHOLESTEROLEMIA

2017 ◽  
Author(s):  
I. I. Yuryk ◽  
Ya. Ya. Bodnar ◽  
V. D. Voloshyn ◽  
Ya. I. Yuryk
Keyword(s):  
Blood Vessels ◽  
Clinical Manifestations ◽  
Vascular Lesions ◽  
Human Organism ◽  
External Diameter ◽  
Morphometric Characteristics ◽  
White Rats ◽  
Hind Limbs ◽  
Age Related ◽  
Experimental Hypercholesterolemia

Background. The human organism is constantly affected by metabolic risk factors. All of them for a long time are asymptomatic and often form in early childhood long before clinical manifestations. However, morphogenesis and morphofunctional features of age-related structural changes in blood vessels of different sites are poorly studied.Objective. To evaluate the morphometric characteristics of arterial bed remodeling of hind limbs in white rats of PRA and RA with experimentally induced hypercholesterolemia.Methods. The tissues biopsies from femoral, knee and shin areas were studied by means of histological and morphometric methods.Results. Experimental hypercholesterolemia caused remodeling of vessels with increasing thickness of medial and endothelial layer of vessels in the investigated parts of the rats’ body. In this case, the external diameter of vessels increased only in femoral area in the reproductive group of rats. In the group of pre-productive animals, the external diameter of the vessels studied was more or less unaffected. Thus, increased thickness of intima and media led to a decrease in arteries capacity. The depth of vascular lesions and the decrease in functional capacity of blood vessels were directly proportional to the duration of the experiment. In the group of reproductive rats, the changes in vascular bed were more evident.Conclusions. Objective study of the processes allows providing a scientific basis for further research and understanding of the pathomorphism of vascular diseases in humans.

Electric Properties of Liquid Metals and Semiconductors

1972 ◽  
Vol 106 (3) ◽  
pp. 393 ◽  
Author(s):  
V.A. Alekseev ◽  
Aleksandr A. Andreev ◽  
V.Ya. Prokhorenko
Keyword(s):  
Liquid Metals ◽  
Electric Properties

Book reviews

2003 ◽  
Vol 51 (2) ◽  
pp. 245-247
Author(s):  
P. Sótonyi ◽  
G. Bodó
Keyword(s):  
Diagnostic Radiology ◽  
Illustrated Text ◽  
Hind Limbs ◽  
Horse Diseases

Klaus-Dieter Budras, Patrick H. McCarthy, Wolfgang Fricke, Renate Richter: Anatomy of the Dog. An Illustrated Text. 4th edition with Aaron Horowitz and Rolf Berg. Schlütersche GmbH & Co. KG Verlag und Druckerei, Hannover, Germany. 222 pages, 71 large-sized colour plates including several illustrations, radiographs, drawings and photographs. 9¾ × 13½", hardcover. ISBN 3-87706-619-4. Price: Ł54 / € 86. Kees J. Dik: Atlas of Diagnostic Radiology of the Horse - Diseases of the Front and Hind Limbs. Second extended and revised edition, Schlütersche, Hannover, 2002. 300 pages with 702 radiographs, 82 drawings. 9¾ ×13½", hardcover. ISBN 3-87706-651-8. Price:€ 144 / USD 179.5 / £ 89.

DEVELOPMENT OF AN EXPERIMENTAL MODEL OF AVITAMINOSIS F

2020 ◽  
Vol 20 (2) ◽  
pp. 38-40
Author(s):  
A. Levitsky ◽  
A. Lapinska ◽  
I. Selivanskaya
Keyword(s):  
Fatty Acids ◽  
Experimental Model ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
The Body ◽  
Regulatory Function ◽  
Omega 3 ◽  
White Rats ◽  
Arachidonic Acids

The article analyzes the role of essential polyunsaturated fatty acids (PUFA), especially omega-3 series in humans and animals. The biosynthesis of essential PUFA in humans and animals is very limited, so they must be consumed with food (feed). Тhe ratio of omega-3 and omega-6 PUFA is very important. Biomembranes of animal cells contain about 30% PUFA with a ratio of ω-6/ ω-3 1-2. As this ratio increases, the physicochemical properties of biomembranes and the functional activity of their receptors change. The regulatory function of essential PUFA is that in the body under the action of oxygenase enzymes (cyclooxygenase, lipoxygenase) are formed extremely active hormone-like substances (eicosanoids and docosanoids), which affect a number of physiological processes: inflammation, immunity, metabolism. Moreover, ω-6 PUFA form eicosanoids, which have pro-inflammatory, immunosuppressive properties, and ω-3 PUFAs form eicosanoids and docosanoids, which have anti-inflammatory and immunostimulatory properties. Deficiency of essential PUFA, and especially ω-3 PUFA, leads to impaired development of the body and its state of health, which are manifestations of avitaminosis F. Prevention and treatment of avitaminosis F is carried out with drugs that contain PUFA. To create new, more effective vitamin F preparations, it is necessary to reproduce the model of vitamin F deficiency. An experimental model of vitamin F deficiency in white rats kept on a fat –free diet with the addition of coconut oil, which is almost completely free of unsaturated fatty acids, and saturated fatty acids make up almost 99 % of all fatty acids was developed. The total content of ω-6 PUFA (sum of linoleic and arachidonic acids), the content of ω-3 PUFA (α-linolenic, eicosapentaenoic and docosahexaenoic acids) in neutral lipids (triglycerides and cholesterol esters) defined. Тhe content of ω-6 PUFA under the influence of coconut oil decreased by 3.3 times, and the content of ω-3 PUFA - by 7.5 times. Тhe influence of coconut oil, the content of ω-6 PUFA decreased by 2.1 times, and the content of ω-3 PUFA - by 2.8 times. The most strongly reduces the content of ω-3 PUFA, namely eicosapentaenoic, coconut oil, starting from 5 %. Consumption of FFD with a content of 15 % coconut oil reduces the content of eicosapentaenoic acid to zero, ie we have an absolute deficiency of one of the most important essential PUFAs, which determined the presence of vitamin F deficiency.

A system of experimental studies of electric properties of rocks in the inert medium

2018 ◽  
Vol 40 (1) ◽  
pp. 93-106
Author(s):  
M. V. Kravchuk ◽  
V. A. Korchyn ◽  
V. P. Kobolev ◽  
N. I. Novik
Keyword(s):  
Experimental Studies ◽  
Electric Properties ◽  
Inert Medium

A new approach to treatment of stomatitis in experiments on white rats (experimental research)

2018 ◽  
pp. 168-173
Author(s):  
Е.Б. Ганина ◽  
Ю.В. Червинец ◽  
Н.В. Грудинин ◽  
В.Г. Шестакова ◽  
В.М. Червинец ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Oral Cavity ◽  
Experimental Research ◽  
Quantitative Composition ◽  
Oral Diseases ◽  
New Approach ◽  
Highly Active ◽  
White Rats ◽  
Before And After ◽  
Intact Rats

Цель исследования - охарактеризовать микробиологическую картину стоматита до и после его лечения высокоактивными культурами лактобацилл, дать оценку эффективности их применения при экспериментальном стоматите. Методика. Опыты проводились на 32 самках беспородных белых крыс массой 230 г. Моделирование стоматита включало 2 этапа: моделирование травматического стоматита и воспроизведение бактериального стоматита на базе травматического. У крыс контрольной и опытных серий на всех этапах эксперимента брали мазки с поверхности десен для характеристики микробиоценоза ротовой полости. Результаты. После обработки слизистой оболочки полости рта (СОПР) культурой патогенного штамма Staphylococcus aureus существенно снизились частота встречаемости и количество условно-патогенных микроорганизмов. Лечение стоматита у крыс культурами лактобацилл ( Lactobacillus 11 зв., Lactobacillus 2 п.рта, Lactobacillus 24 д.ст.) и их комбинацией приводило к снижению распространенности S. aureus вплоть до его исчезновения, а также к нормализации количества условно-патогенной микробиоты. Заключение. Исследования показали эффективность использования отдельных высокоактивных штаммов лактобацилл или их комбинации при лечении заболеваний СОПР, в частности бактериального стоматита. Aim. To characterize the microbiological picture of stomatitis in intact rats before and after the treatment with highly active cultured lactobacilli and to evaluate the effectiveness of this treatment in experiments on white rats. Methods. Experiments were carried out on 32 mongrel female white rats weighing 230 g. Smears were taken from the gum surface of control and experimental rats at all stages of the experiment to characterize the oral cavity microbiocenosis. Results. After treatment of the oral cavity with cultured Staphylococcus aureus , the occurrence and quantity of opportunistic microorganisms significantly decreased. The treatment of stomatitis in rats with cultured lactobacillus ( Lactobacillus 11 zv., Lactobacillus 2 p.r., Lactobacillus 24 d.st. and their combination) led to a decrease in S. aureus prevalence up to its extinction and to normalization of the quantitative composition of opportunistic microbiota. Conclusions. The study showed the effieacy of highly active lactobacillus strains individually or their combinations in the treatment of oral diseases, in particular, bacterial stomatitis.

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