scholarly journals How Does a Supervised Exercise Program Improve Quality of Life in Patients with Cancer? A Concept Mapping Study Examining Patients' Perspectives

2018 ◽  
Vol 24 (6) ◽  
Author(s):  
Maike G. Sweegers ◽  
Laurien M. Buffart ◽  
Wouke M. van Veldhuizen ◽  
Edwin Geleijn ◽  
Henk M.W. Verheul ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Concept Mapping ◽  
Exercise Program ◽  
Improve Quality ◽  
Mapping Study ◽  
Patients With Cancer ◽  
Supervised Exercise ◽  
Supervised Exercise Program

Randomized clinical trial on the effect of a supervised exercise program on quality of life, fatigue, and fitness following esophageal cancer treatment (PERFECT study).

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 12055-12055
Author(s):  
Anne Maria May ◽  
Jonna van Vulpen ◽  
Anouk E Hiensch ◽  
Jelle P. Ruurda ◽  
Grard Nieuwenhuijzen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Esophageal Cancer ◽  
Cardiorespiratory Fitness ◽  
Exercise Intervention ◽  
Exercise Program ◽  
Post Intervention ◽  
Supervised Exercise ◽  
Supervised Exercise Program

12055 Background: Patients with potentially curable esophageal cancer are often treated with chemoradiotherapy followed by surgery. This treatment might have a negative impact on physical fitness, fatigue and quality of life (QoL). In patients with other types of cancer, evidence suggests that physical exercise reduces treatment related side effects. We investigated whether a supervised exercise program also beneficially affects QoL, fatigue and cardiorespiratory fitness (CRF) in patients after treatment for esophageal cancer. Methods: The multicenter PERFECT study randomly assigned patients in the first year after esophagectomy to an exercise intervention (EX) or usual care (UC) group. EX patients participated in a 12-week moderate to high intensity aerobic and resistance exercise program supervised by a physiotherapist. UC patients were advised to maintain their physical activity levels. Attendance and compliance with the exercise intervention protocol were retrieved from exercise logs. QoL (primary outcome, EORTC-QLQ-30, range 0-100), fatigue (MFI-20, range 4-20) and CRF (cardiopulmonary exercise testing) were assessed at baseline and after 12 weeks (post-intervention). The outcomes were analyzed as between-group differences using either linear mixed effects models or ANCOVA adjusted for baseline and stratification factors (i.e. sex, time since surgery, center), according to the intention-to-treat principle. Results: A total of 120 patients (age 64±8) were included and randomized to EX (n = 61) or UC (n = 59). Patients in the EX group participated in 96% (IQR:92-100%) of the supervised exercise sessions and compliance with all parts of the exercise program was high ( > 90%). Post-intervention, global QoL was not statistically different between groups, but significant (p < 0.05) beneficial EX effects were found for QoL-Summary scores (between-group difference 3.5, 95% CI 0.2;6.8) and QoL-role functioning (9.4, 1.3;17.5). Physical fatigue wat non-significantly lower in the EX group (-1.2; -2.6;0.1, p = 0.08). CRF was significantly higher (VO2peak (1.8 mL/min/kg, 0.6;3.0) following the EX intervention. Conclusions: Patients were well capable to complete an intensive supervised exercise program after esophageal cancer treatment, which led to small but significant improvements in several aspects of QoL and cardiorespiratory fitness. Our results suggest that supervised exercise is a beneficial addition to routine care of patients with esophageal cancer. Clinical trial information: NTR5045 .

Quality of Life Benefits in Cancer Survivorship with Supervised Exercise

2009 ◽  
Vol 104 (2) ◽  
pp. 421-424 ◽  
Author(s):  
Matthew S. Wiggins ◽  
Emily M. Simonavice
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Exercise Program ◽  
Well Being ◽  
Bicycle Ergometer ◽  
Physically Active ◽  
Cancer Support ◽  
Supervised Exercise ◽  
Supervised Exercise Program

To assess whether a supervised exercise program would benefit cancer survivors' perceived psychological well-being over the course of a 6-mo. program, 8 female and 2 male cancer survivors, ages 45 to 69 ( M = 56.2, SD = 8.1) were recruited into the program from a presentation given to a breast-cancer support group and by word of mouth. Activity sessions were two times per week and typically involved treadmill and bicycle ergometer time, plus eight to ten weight-training stations. A quality of life measure was taken at baseline, 3, and 6 mo. Analyses showed a significant increase in quality of life from baseline to 3 mo. and from baseline to 6 mo. Being physically active in a supervised exercise program provided increased perceived benefits in quality of life for these cancer survivors over 6 mo.

All Patients Benefit Equally From a Supervised Exercise Program for Claudication

2007 ◽  
Vol 41 (3) ◽  
pp. 212-216 ◽  
Author(s):  
Ferdinand Serracino-Inglott ◽  
Gareth Owen ◽  
Andrew Carter ◽  
Francis Dix ◽  
John Vince Smyth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Exercise Program ◽  
Walking Distance ◽  
Supervised Exercise ◽  
Diabetic Status ◽  
Heterogenous Group ◽  
Cardiac Status ◽  
Supervised Exercise Program

This study assessed the effect of gender, diabetic status, statin use, smoking, hypertension, cardiac status, and use of cilostazol on the outcome of a supervised exercise program for patients with claudication. Patient risk factors were prospectively recorded in a group of patients who had completed 1 year on a supervised exercise program. In 165 claudicant patients, maximum walking distance increased ( P < .0001) from 67 meters (range, 17-196) to 122 meters (range, 43-409). Quality of life as measured by the Medical Outcome Study Short Form 36 increased ( P < .0001) from a median of 78 (range, 55-110) to 99 (range, 71-154). The improvements in claudication distance, maximal walking distance, and quality of life after the exercise program were not dependent on any of the measured patient factors. Patients referred to exercise programs for claudication are a heterogenous group. Despite this, they benefit equally from such a program.

Effect of Supervised Exercise Program on Individuals in Peripheral Arterial Disease with Type 2 Diabetes Mellitus - A Systematic Review

2020 ◽  
Vol 16 (3) ◽  
pp. 248-253
Author(s):  
Esha Arora ◽  
Arun G. Maiya ◽  
Tom Devasia ◽  
Rama Bhat ◽  
Ganesh Kamath
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Ankle Brachial Index ◽  
Exercise Program ◽  
Arterial Disease ◽  
Supervised Exercise ◽  
Peripheral Arterial ◽  
Supervised Exercise Program

Background: Type 2 Diabetes Mellitus (T2DM) is usually accompanied by various micro and macro vascular complications. Peripheral Arterial Disease (PAD) is one of the major complications of diabetes which is accountable for morbidity and mortality throughout the world. The first line of treatment in these individuals is life style modification and exercise. There is a dearth of literature on effect of supervised exercise program in PAD with T2DM on quality of life, walking impairment, change in Ankle Brachial Index (ABI) values. So, we conducted a systematic review to explore the available literature on supervised exercise program in PAD with T2DM. Methods: We conducted a systematic review (PubMed, Web of Science, CINAHL and Cochrane) to summarise the evidence on a supervised exercise program in PAD with T2DM. Randomised and nonrandomised studies were included in the review. Results: Three studies met the inclusion criteria. The outcomes taken into accounts by the studies were the quality of life, walking impairment questionnaire, Ankle brachial index. Neither of the studies matched in their supervised exercise program nor in their outcome. Conclusion: In conclusion, the data evaluating the supervised exercise program in PAD with T2DM is inadequate to determine its effect on this population. Future large-scale studies can be conducted on both subjective and objective outcomes of PAD with T2DM to have a better understanding of the condition and for a universally acceptable exercise program for these individuals which the healthcare practitioners can use in their practice.

scholarly journals An Activity Tracker–Guided Physical Activity Program for Patients Undergoing Radiotherapy: Protocol for a Prospective Phase III Trial (OnkoFit I and II Trials) (Preprint)

2021 ◽  
Author(s):  
Franziska Hauth ◽  
Barbara Gehler ◽  
Andreas Michael Nieß ◽  
Katharina Fischer ◽  
Andreas Toepell ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Functional Assessment ◽  
Exercise Program ◽  
Daily Step ◽  
Patients With Cancer ◽  
Activity Tracker ◽  
Cancer Related Fatigue ◽  
Daily Step Count

BACKGROUND The positive impact that physical activity has on patients with cancer has been shown in several studies over recent years. However, supervised physical activity programs have several limitations, including costs and availability. Therefore, our study proposes a novel approach for the implementation of a patient-executed, activity tracker–guided exercise program to bridge this gap. OBJECTIVE Our trial aims to investigate the impact that an activity tracker–guided, patient-executed exercise program for patients undergoing radiotherapy has on cancer-related fatigue, health-related quality of life, and preoperative health status. METHODS Patients receiving postoperative radiotherapy for breast cancer (OnkoFit I trial) or neoadjuvant, definitive, or postoperative treatment for other types of solid tumors (OnkoFit II trial) will be randomized (1:1:1) into 3-arm studies. Target accrual is 201 patients in each trial (50 patients per year). After providing informed consent, patients will be randomized into a standard care arm (arm A) or 1 of 2 interventional arms (arms B and C). Patients in arms B and C will wear an activity tracker and record their daily step count in a diary. Patients in arm C will receive personalized weekly targets for their physical activity. No further instructions will be given to patients in arm B. The target daily step goals for patients in arm C will be adjusted weekly and will be increased by 10% of the average daily step count of the past week until they reach a maximum of 6000 steps per day. Patients in arm A will not be provided with an activity tracker. The primary end point of the OnkoFit I trial is cancer-related fatigue at 3 months after the completion of radiotherapy. This will be measured by the Functional Assessment of Chronic Illness Therapy-Fatigue questionnaire. For the OnkoFit II trial, the primary end point is the overall quality of life, which will be assessed with the Functional Assessment of Cancer Therapy-General sum score at 6 months after treatment to allow for recovery after possible surgery. In parallel, blood samples from before, during, and after treatment will be collected in order to assess inflammatory markers. RESULTS Recruitment for both trials started on August 1, 2020, and to date, 49 and 12 patients have been included in the OnkoFit I and OnkoFit II trials, respectively. Both trials were approved by the institutional review board prior to their initiation. CONCLUSIONS The OnkoFit trials test an innovative, personalized approach for the implementation of an activity tracker–guided training program for patients with cancer during radiotherapy. The program requires only a limited amount of resources. CLINICALTRIAL ClinicalTrials.gov NCT04506476; https://clinicaltrials.gov/ct2/show/NCT04506476. ClinicalTrials.gov NCT04517019; https://clinicaltrials.gov/ct2/show/NCT04517019. INTERNATIONAL REGISTERED REPORT DERR1-10.2196/28524

A Supervised Group Exercise Program for Patients with Multiple Myeloma.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 5171-5171
Author(s):  
Christine I. Chen ◽  
Danielle Rolfe ◽  
Faith Delosreyes ◽  
Devi Ahuja ◽  
Christina Lee
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Pain Treatment ◽  
Depression Scale ◽  
Exercise Program ◽  
Pilot Program ◽  
Group Setting ◽  
Supervised Exercise ◽  
Peak Vo2

Abstract Background: Cancer-related fatigue, anemia, bone pain, treatment toxicities, depression, and advanced age contribute to debilitation in myeloma. Myeloma pts are reluctant to exercise due to lack of disease-specific exercise guidelines and fear of injury. At our centre, a disease-modified, supervised exercise pilot program has been evaluated with 20 subjects. Methods: Subjects attending myeloma clinic were accrued over 6 wks in response to posted notices. Eligibility: no recent bone fracture/radiation, max. MET (metabolic equivalent) ≥6 (21mL O2 consumption/kg/min, VO2) sufficient to undergo regular exercise (DASI screen). The 12 wk program included weekly supervised group sessions (90 min) and individualized home-based exercises (twice weekly). Exercises were based on American College of Sports Medicine guidelines modified to cancer pts (Lucia et al 2003) and outlined in a manual. Exercises: 1) low-intensity aerobic (treadmills, track walking, recumbent cycle ergometers to 45–75% max. HR); 2) resistance training (therabands, balls, hand wts, or body wt); 3) flexibility training (stretch exercises). Subjects were assessed at baseline and 12 wks for: 1) body composition (wt, BMI, bioelectrical impedence); 2) fitness (HR, peak VO2, max. grip strength, endurance, flexibility measures); 3) quality of life (FACT-F questionnaire); 4) pain (Brief pain inventory); 5) mental health (Hospital Anxiety Depression Scale). Results: 20 subjects took part in the pilot program: 6M:14F; median age 60 yrs(42–74); median disease duration 29 mos(15mos–14yrs); median prior therapies 3(0–8); prior ASCT 16/20 - median time from ASCT 20 mos(3mos–12 yrs), 15/20 with bone disease/pain, 10/20 on active myeloma therapy. Comorbidities: 10/20 had lung, arthritis, or heart disease; 2/20 active smokers. Median Hb 116g/L (range 81–147) - 5/20 subjects had Hb≤100g/L. 18/20 subjects completed the 12 wk program (2 dropouts: 1 hospitalization, 1 unexpected travel). Attendance was variable - 24%(54/216) of total visits missed, most due to minor illness or disease/medication complications. Monthly program evaluations showed enthusiasm for the group format with individualized instruction helping to allay fears of injury. Despite weekly travel, subjects preferred the group setting vs home exercises alone, citing motivation from peers/instructors as vital. Conclusions: A formal exercise program for myeloma is feasible with potential benefits in fitness and mental health. Detailed exercise diagrams/video, expanded strength training, and increased individualized time to ensure proper technique were suggestions for incorporation into our current program. A planned RCT comparing our tailored exercise program to standard care will help develop a prescription for maintaining longterm quality of life for myeloma survivors. Mean baseline (SD) Mean Wk 12 (SD) Difference P-value (paired t-test) *Difference post-6 min walk to resting HR* 45 (18) 44 (19) −1.5 (21) 0.797 SBP* 21.4 (10.7) 18.5 (16.2) −2.9 (13.0) 0.427 6min walk 548 (102) 588 (114) 40 (48) 0.008 Peak VO2 12.6 (1.7) 13.3 (1.9) 0.7 (0.8) 0.007 Wt (kg) 72.6 (11.4) 71.8 (11.6) −0.8 (2.8) 0.320 BMI (Wt/Ht2) 27.5 (4.1) 27.2 (4.4) −0.3 (1.0) 0.328 Body fat (%) 34.7 (6.8) 34.8 (6.7) 0.0 (1.3) 0.328 Strength test 11.5 (3.2) 14.9 (5.6) 3.4 (3.4) 0.005 Flexibility test 20.4 (5.6) 22.9 (8.9) 2.5 (7.6) 0.288 FACT-F 113.7 (22.5) 117.6 (24.1) 3.9 (11.7) 0.214 HAD scale 6.5 (2.4) 5.2 (2.5) −1.2 (1.6) 0.012

scholarly journals An Activity Tracker–Guided Physical Activity Program for Patients Undergoing Radiotherapy: Protocol for a Prospective Phase III Trial (OnkoFit I and II Trials)

10.2196/28524 ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. e28524
Author(s):  
Franziska Hauth ◽  
Barbara Gehler ◽  
Andreas Michael Nieß ◽  
Katharina Fischer ◽  
Andreas Toepell ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Functional Assessment ◽  
Exercise Program ◽  
Daily Step ◽  
Patients With Cancer ◽  
Activity Tracker ◽  
Cancer Related Fatigue ◽  
Daily Step Count

Background The positive impact that physical activity has on patients with cancer has been shown in several studies over recent years. However, supervised physical activity programs have several limitations, including costs and availability. Therefore, our study proposes a novel approach for the implementation of a patient-executed, activity tracker–guided exercise program to bridge this gap. Objective Our trial aims to investigate the impact that an activity tracker–guided, patient-executed exercise program for patients undergoing radiotherapy has on cancer-related fatigue, health-related quality of life, and preoperative health status. Methods Patients receiving postoperative radiotherapy for breast cancer (OnkoFit I trial) or neoadjuvant, definitive, or postoperative treatment for other types of solid tumors (OnkoFit II trial) will be randomized (1:1:1) into 3-arm studies. Target accrual is 201 patients in each trial (50 patients per year). After providing informed consent, patients will be randomized into a standard care arm (arm A) or 1 of 2 interventional arms (arms B and C). Patients in arms B and C will wear an activity tracker and record their daily step count in a diary. Patients in arm C will receive personalized weekly targets for their physical activity. No further instructions will be given to patients in arm B. The target daily step goals for patients in arm C will be adjusted weekly and will be increased by 10% of the average daily step count of the past week until they reach a maximum of 6000 steps per day. Patients in arm A will not be provided with an activity tracker. The primary end point of the OnkoFit I trial is cancer-related fatigue at 3 months after the completion of radiotherapy. This will be measured by the Functional Assessment of Chronic Illness Therapy-Fatigue questionnaire. For the OnkoFit II trial, the primary end point is the overall quality of life, which will be assessed with the Functional Assessment of Cancer Therapy-General sum score at 6 months after treatment to allow for recovery after possible surgery. In parallel, blood samples from before, during, and after treatment will be collected in order to assess inflammatory markers. Results Recruitment for both trials started on August 1, 2020, and to date, 49 and 12 patients have been included in the OnkoFit I and OnkoFit II trials, respectively. Both trials were approved by the institutional review board prior to their initiation. Conclusions The OnkoFit trials test an innovative, personalized approach for the implementation of an activity tracker–guided training program for patients with cancer during radiotherapy. The program requires only a limited amount of resources. Trial Registration ClinicalTrials.gov NCT04506476; https://clinicaltrials.gov/ct2/show/NCT04506476. ClinicalTrials.gov NCT04517019; https://clinicaltrials.gov/ct2/show/NCT04517019. International Registered Report Identifier (IRRID) DERR1-10.2196/28524

Sign in / Sign up

Export Citation Format

Share Document