scholarly journals Risk of Second Primary Thyroid Cancer after Radiotherapy for a Childhood Cancer in a Large Cohort Study: An Update from the Childhood Cancer Survivor Study

2010 ◽  
Vol 174 (6a) ◽  
pp. 741-752 ◽  
Author(s):  
Parveen Bhatti ◽  
Lene H. S. Veiga ◽  
Cécile M. Ronckers ◽  
Alice J. Sigurdson ◽  
Marilyn Stovall ◽  
...  
Keyword(s):  
Cohort Study ◽  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Large Cohort ◽  
Childhood Cancer Survivor ◽  
Second Primary ◽  
Large Cohort Study ◽  
Childhood Cancer Survivor Study

scholarly journals Second primary neoplasms in survivors of Wilms' tumour-A population-based cohort study from the British Childhood Cancer Survivor Study

2008 ◽  
Vol 122 (9) ◽  
pp. 2085-2093 ◽  
Author(s):  
Aliki J. Taylor ◽  
David L. Winter ◽  
Kathy Pritchard-Jones ◽  
Charles A. Stiller ◽  
Clare Frobisher ◽  
...  
Keyword(s):  
Cohort Study ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Population Based ◽  
Childhood Cancer Survivor ◽  
Second Primary ◽  
Wilms Tumour ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms ◽  
Childhood Cancer Survivor Study

scholarly journals Predicting acute ovarian failure in female survivors of childhood cancer: a cohort study in the Childhood Cancer Survivor Study (CCSS) and the St Jude Lifetime Cohort (SJLIFE)

2020 ◽  
Vol 21 (3) ◽  
pp. 436-445 ◽  
Author(s):  
Rebecca A Clark ◽  
Sogol Mostoufi-Moab ◽  
Yutaka Yasui ◽  
Ngoc Khanh Vu ◽  
Charles A Sklar ◽  
...  
Keyword(s):  
Cohort Study ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Ovarian Failure ◽  
Childhood Cancer Survivor ◽  
Female Survivors ◽  
Childhood Cancer Survivor Study ◽  
Survivors Of Childhood Cancer

scholarly journals Chemotherapy and Thyroid Cancer Risk: A Report from the Childhood Cancer Survivor Study

2011 ◽  
Vol 21 (1) ◽  
pp. 92-101 ◽  
Author(s):  
Lene H.S. Veiga ◽  
Parveen Bhatti ◽  
Cécile M. Ronckers ◽  
Alice J. Sigurdson ◽  
Marilyn Stovall ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Childhood Cancer Survivor ◽  
Thyroid Cancer Risk ◽  
Childhood Cancer Survivor Study

042: Radiation and Thyroid Cancer in the Childhood Cancer Survivor Study: A Detailed Evaluation of Dose-Response and its Modifiers

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S11-S11
Author(s):  
C Ronckers ◽  
A Sigurdson ◽  
M Stovall ◽  
S Smith ◽  
C Sklar ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Dose Response ◽  
Childhood Cancer Survivor ◽  
Detailed Evaluation ◽  
Childhood Cancer Survivor Study

Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study): a nested case-control study

The Lancet ◽  
2005 ◽  
Vol 365 (9476) ◽  
pp. 2014-2023 ◽  
Author(s):  
Alice J Sigurdson ◽  
Cécile M Ronckers ◽  
Ann C Mertens ◽  
Marilyn Stovall ◽  
Susan A Smith ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Case Control Study ◽  
Case Control ◽  
Childhood Cancer Survivor ◽  
Childhood Cancer Survivor Study ◽  
Nested Case Control ◽  
Control Study

Abstract 600: Telomere length-associated genetic variants and the risk of thyroid cancer after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS)

2018 ◽  
Author(s):  
Philip J. Lupo ◽  
Lindsay M. Morton ◽  
Yutaka Yasui ◽  
Wendy M. Leisenring ◽  
Gregory T. Armstrong ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Telomere Length ◽  
Cancer Survivor ◽  
Genetic Variants ◽  
Childhood Cancer Survivor ◽  
Childhood Cancer Survivor Study

scholarly journals Risk of thyroid cancer in survivors of childhood cancer: Results from the British Childhood Cancer Survivor Study

2009 ◽  
Vol 125 (10) ◽  
pp. 2400-2405 ◽  
Author(s):  
Aliki J. Taylor ◽  
Adam P. Croft ◽  
Aimee M. Palace ◽  
David L. Winter ◽  
Raoul C. Reulen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Childhood Cancer Survivor ◽  
Childhood Cancer Survivor Study ◽  
Survivors Of Childhood Cancer

scholarly journals Telomere Length-Associated Genetic Variants and the Risk of Thyroid Cancer in Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study (CCSS)

2018 ◽  
Vol 28 (2) ◽  
pp. 417-419 ◽  
Author(s):  
Maria M. Gramatges ◽  
Lindsay M. Morton ◽  
Yutaka Yasui ◽  
Michael A. Arnold ◽  
Joseph P. Neglia ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Childhood Cancer ◽  
Telomere Length ◽  
Cancer Survivor ◽  
Genetic Variants ◽  
Childhood Cancer Survivor ◽  
Childhood Cancer Survivor Study ◽  
Survivors Of Childhood Cancer

scholarly journals Risk of thyroid dysfunction and subsequent thyroid cancer among survivors of acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study

2009 ◽  
Vol 53 (3) ◽  
pp. 432-437 ◽  
Author(s):  
Eric J. Chow ◽  
Debra L. Friedman ◽  
Marilyn Stovall ◽  
Yutaka Yasui ◽  
John A. Whitton ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Acute Lymphoblastic Leukemia ◽  
Childhood Cancer ◽  
Cancer Survivor ◽  
Thyroid Dysfunction ◽  
Lymphoblastic Leukemia ◽  
Childhood Cancer Survivor ◽  
Childhood Cancer Survivor Study

scholarly journals Population-Based Risks of CNS Tumors in Survivors of Childhood Cancer: The British Childhood Cancer Survivor Study

2010 ◽  
Vol 28 (36) ◽  
pp. 5287-5293 ◽  
Author(s):  
Aliki J. Taylor ◽  
Mark P. Little ◽  
David L. Winter ◽  
Elaine Sugden ◽  
David W. Ellison ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Cancer Survivor ◽  
Population Based ◽  
Childhood Cancer Survivor ◽  
Cns Tumors ◽  
Intrathecal Methotrexate ◽  
Second Primary ◽  
National Population ◽  
Childhood Cancer Survivor Study ◽  
Survivors Of Childhood Cancer

Purpose CNS tumors are the most common second primary neoplasm (SPN) observed after childhood cancer in Britain, but the relationship of risk to doses of previous radiotherapy and chemotherapy is uncertain. Methods The British Childhood Cancer Survivor Study is a national, population-based, cohort study of 17,980 individuals surviving at least 5 years after diagnosis of childhood cancer. Linkage to national, population-based cancer registries identified 247 SPNs of the CNS. Cohort and nested case-control studies were undertaken. Results There were 137 meningiomas, 73 gliomas, and 37 other CNS neoplasms included in the analysis. The risk of meningioma increased strongly, linearly, and independently with each of dose of radiation to meningeal tissue and dose of intrathecal methotrexate. Those whose meningeal tissue received 0.01 to 9.99, 10.00 to 19.99, 20.00 to 29.99, 30.00 to 39.99 and ≥ 40 Gy had risks that were two-fold, eight-fold, 52-fold, 568-fold, and 479-fold, respectively, the risks experienced by those whose meningeal tissue was unexposed. The risk of meningioma among individuals receiving 1 to 39,40 to 69, and at least 70 mg/m2 of intrathecal methotrexate was 15-fold, 11-fold, and 36-fold, respectively, the risk experienced by those unexposed. The standardized incidence ratio for gliomas was 10.8 (95% CI, 8.5 to 13.6). The risk of glioma/primitive neuroectodermal tumors increased linearly with dose of radiation, and those who had CNS tissue exposed to at least 40 Gy experienced a risk four-fold that experienced by those who had CNS tissue unexposed. Conclusion The largest-ever study, to our knowledge, of CNS tumors in survivors of childhood cancer indicates that the risk of meningioma increases rapidly with increased dose of radiation to meningeal tissue and with increased dose of intrathecal methotrexate.

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