scholarly journals Thyroid and pituitary thyroxine-5'-deiodinase activity and thyrotrophin secretion in lithium-treated rats

2002 ◽  
Vol 174 (2) ◽  
pp. 331-334 ◽  
Author(s):  
TG Frankenfeld ◽  
VM Correa Da Costa ◽  
CC Nascimento-Saba ◽  
TM Ortiga-Carvalho ◽  
RM Santos ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Lithium Treatment ◽  
The Other ◽  
Other Hand ◽  
Deiodinase Activity ◽  
First Time ◽  
Serum Tsh ◽  
Tsh Levels

Some authors have reported increased serum thyrotrophin (TSH) in animals chronically treated with lithium, suggesting that lithium might decrease pituitary thyroxine (T(4))-5'-deiodinase activity. On the other hand, the effect of lithium treatment on thyroidal T(4)-5'-deiodinase activity is also unknown. The present study was undertaken to evaluate the effects of lithium treatment on pituitary and thyroid T(4)-5'-deiodinase activity. Serum and pituitary TSH levels and thyroidal and pituitary T(4)-5'-deiodinase activities were determined in 3-month-old isogenic male Dutch-Miranda rats treated with lithium for 8 weeks. Chronic lithium treatment produced a slight increase in pituitary TSH content, but no change in serum TSH, and a significant increase in the thyroidal T(4)-5'-deiodinase activity. However, the pituitary T(4)-5'-deiodinase activity was unaffected by lithium administration. As far as we know, the present data show for the first time that chronic lithium treatment can increase the thyroxine to tri-iodothyronine conversion in the murine thyroid gland, be it directly or indirectly.

A Nabatean port on the Red Sea: note on the pottery finds from al-Qusayr (al-Wajh, Saudi Arabia)

2020 ◽  
Author(s):  
Caroline Durand
Keyword(s):  
Saudi Arabia ◽  
19Th Century ◽  
Red Sea ◽  
Point Of View ◽  
The Other ◽  
Trade Routes ◽  
Other Hand ◽  
Roman Egypt ◽  
Pottery Sherds ◽  
First Time

Al-Qusayr is located 40 km south of modern al-Wajh, roughly 7 km from the eastern Red Sea shore. This site is known since the mid-19th century, when the explorer R. Burton described it for the first time, in particular the remains of a monumental building so-called al-Qasr. In March 2016, a new survey of the site was undertaken by the al-‘Ula–al-Wajh Survey Project. This survey focused not only on al-Qasr but also on the surrounding site corresponding to the ancient settlement. A surface collection of pottery sherds revealed a striking combination of Mediterranean and Egyptian imports on one hand, and of Nabataean productions on the other hand. This material is particularly homogeneous on the chronological point of view, suggesting a rather limited occupation period for the site. Attesting contacts between Mediterranean merchants, Roman Egypt and the Nabataean kingdom, these new data allow a complete reassessment of the importance of this locality in the Red Sea trade routes during antiquity.

scholarly journals On the embedding of a group in a join of given groups

1974 ◽  
Vol 17 (4) ◽  
pp. 434-495 ◽  
Author(s):  
P. Hall
Keyword(s):  
Countable Group ◽  
The Other ◽  
Other Hand ◽  
First Time ◽  
Fundamental Paper

1. In their fundamental paper of 1949, Higman, Neumann and Neumann proved for the first time that a countable group can always be embedded in some 2-generator group: [1], Theorem IV. Two kinds of improvement of this result have recently appeared. In [4], Theorem 2, Dark has shown that the embedding can always be made subnormally. On the other hand, in [2], Theorem 2.1, Levin has shown that the two generators can be given preassigned orders m > 1 and n > 2; and in [3], Miller and Schupp prove that the 2-generator group can also be made to satisfy several additional requirements, such as being complete and Hopfian.

Beneficial effect of lithium in female patient with bipolar affective illness and psoriasis

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Przemysław Filipiak ◽  
Anna Jaskóła ◽  
Karolina Gattner
Keyword(s):  
Bipolar Disorder ◽  
Case Report ◽  
Beneficial Effect ◽  
Female Patient ◽  
Lithium Treatment ◽  
The Other ◽  
Patient Needs ◽  
Affective Illness ◽  
First Time

Objectives. Psoriasis makes a relative contraindication for lithium treatment which can exacerbate its symptoms or induce it itself. On the other hand, lithium exerts immuno-modulatory activity. Case study. In this paper, a case of a female patient is presented. The patient has been treated since 2012 for bipolar affective illness (bipolar disorder – BD) and psori­asis, which occurred for the first time during a depress­ive episode. Despite intensive pharmacological treatment, both as inpatient and outpatient, a satisfactory improvement of affective illness has not been obtained. After the introduction of lithium, a remission of BD was achieved as well as a reduction of psoriatic changes, which have been maintained until now (2021). Conclusion. The remission of Bipolar Disorder (BD) on lithium can suggest that the patient belongs to the group of the so-called excellent lithium responders. In the presen­ted case remission of psoriasis was observed during lithium treatment. This case report must be treated with caution because remission could be spontaneous and the patient needs further observation.

scholarly journals On the comparative anatomy of the thyroid gland

1851 ◽  
Vol 5 ◽  
pp. 514-515
Keyword(s):  
Thyroid Gland ◽  
Comparative Anatomy ◽  
The Other ◽  
Other Hand ◽  
Uniform Law ◽  
The One

The author, considering that the careful dissections of Meckel and Cuvier have fully established the universal existence of a thyroid gland in the whole of the class Mammalia, proceeds to consider the comparative anatomy of this organ in the remaining classes of vertebrated animals. His dissections of birds have included all the orders, and, in most instances, several families from each: he has never failed to find in them a thyroid gland, and, with the aid of the microscope, to recognise its peculiar structure; he presumes, therefore, that it is universally present in that class of animals. He has also detected the presence of this organ in reptiles of every order; although generally either wholly overlooked by anatomists, or mistaken for the thymus. Descriptions are here given of its appearance, position and structure in different families of Chelonia, Sauria, Ophidia and Batrachia. In the class of Fishes, it is by no means universally or even generally present. The author has found it in the carp, anableps, pike, exocetus, cod, haddock, whiting, eel, sturgeon, callorhynchus, shark and skate, and perhaps in the lamprey. On the other hand, it appears to be absent in the perch, mullet, gurnard, mackerel, tench, salmon, trout, herring, plaice, halibut, turbot, sole, cyclopterus, gymnotus and balistes. The general conclusion which the author deduces from his researches is, that the distribution of the thyroid gland is regulated by a simple and uniform law; being dependent on the existence or nonexistence of another organ with which its presence alternates, and which, in many fishes, assumes the form of a minute supplementary gill, the vessels of which communicate, on the one hand, with the systemic veins about the base of the cranium, and on the other, by a single long trunk with the first branchial vein.

Vladimir Titov’s Letter to Vladimir Odoevsky as a Well-Known Response to Ivan Turgenev’s Article “Hamlet and Don Quixote” (Contemporaries’ Reception of Turgenev’s Interpretation of the Image of Hamlet)

2021 ◽  
pp. 104-116
Author(s):  
Ivan O. Volkov ◽  
Keyword(s):  
German Idealism ◽  
Don Quixote ◽  
The Other ◽  
National Library ◽  
Other Hand ◽  
The One ◽  
Definition Of ◽  
First Time

For the first time, in the article, Vladimir Titov’s letter (dated 12/24 February 1869) is published and commented. In the 1820s, in Russia, Titov was well-known as a writer and literature theorist, the author of a romantic novella The Remote House on Vasilyevsky Island (1829) close to Society of Lyubomudriye. The letter extracted from the archives of the National Library of Russia is addressed to Duke Vladimir Odoevsky whose relationship with Titov was friendly from the very beginning of their acquaintance. The letter focuses on Ivan Turgenev’s speech published in the first issue of Sovremennik and titled “Hamlet and Don Quixote”. Reacting to Turgenev’s article, Titov shortly and critically accesses the comparison concentrating mainly on the image of Hamlet and thoroughly expresses his opinion on the essence of his tragic state. Titov’s opinion is just the opposite of Turgenev’s complex and multidimensional interpretation. Having experienced the great impact of the philosophy of German idealism at the beginning of his career, Titov to a great extent idealizes Shakespeare’s character whom he long knows and whom he is clearly eager to vindicate. Meanwhile, Titov does not pursue the aim to absolutely advocate the romantic halo of Hamlet as a Titanic personality (grandiose intellect and scale of feeling) and to enact the tragic pathos of the inner fight only. Developing Goethe’s definition of the essence of the character’s inner conflict, Titov, on the one hand, approaches its real understanding underlying the prince’s necessity to stay in a derogatory position of a “pitiful semiclown, indecisive grouch and shred”. On the other hand, the assessment can not be absolutely objective because Titov wants to see Hamlet as a victim of the fatal fortune which turns him into a character of an almost classical tragedy of fate. Titov’s bright and developed reaction (in the document of private nature) to Turgenev’s article is attractive and important first of all for its vividly demonstrated novelty and creativity of the writer’s view, wideness and multimodality of the author’s perception of Hamlet’s image. For the first time, Turgenev gave a developed interpretation of Shakespeare’s image in the tale “Hamlet of Shchigrovsky Province” (1848). Continuing his searches in the area of “Russian” (or “steppe”) Hamlet, Turgenev creates moral and philosophical problems of the English tragedy in the crisis socio-historical and cultural atmosphere of Russia of the 1840s. However, the principles of the artistic generalization and the peculiarities of the new reading, not mentioned and not fully comprehended by his contemporaries, were surprising and rejected when the speech “Hamlet and Don Quixote” appeared, in which Shakespeare’s character is presented ultimately vividly and lively in the then current interpretation.

FROM “CALM CHAOS” TO “COLIBRI”. THE WORKS OF SANDRO VERONESI

2021 ◽  
pp. 122-131
Author(s):  
Tatiana A. Bystrova ◽  
Keyword(s):  
Italian Literature ◽  
The Other ◽  
The Novel ◽  
High Demand ◽  
Surrounding World ◽  
Other Hand ◽  
The One ◽  
First Time

The paper examines two key novels by Sandro Veronesi, the modern Italian writer, Calm Chaos (2006) and Colibri (2020). Both novels were awarded Italy’s main literary prize, the Premio Strega, which is a unique precedent. The relevance of the article comes from the high demand for research on contemporary Italian literature on the one hand and from the novelty of the proposed interpretation for the novel Calm Chaos on the other hand. For the first time, the protagonist of Calm Chaos, Pietro Palladini, is presented not as a preacher of eternal values, returning the reader to the theme of knowing oneself and the surrounding world, but as a mad visionary with clear signs of psychopathy and schizophrenia. The analysis of Veronesi’s latest novel Colibri reveals the character’s evolution and the writer’s narrative manner. The theme of psychiatry in the life of a modern person appears to be one of the key ones in Veronesi’s work.

9. An introduction to copyright

2019 ◽  
pp. 173-176
Author(s):  
Paul Torremans
Keyword(s):  
Literary Work ◽  
The Other ◽  
Printing Press ◽  
Other Hand ◽  
Key Concepts ◽  
The One ◽  
Exclusive Right ◽  
First Time

This chapter first discusses the two roots of copyright. On the one hand, copyright began as an exclusive right to make copies—that is, to reproduce the work of an author. This entrepreneurial side of copyright is linked in with the invention of the printing press, which made it much easier to copy a literary work and, for the first time, permitted the entrepreneur to make multiple identical copies. On the other hand, it became vital to protect the author now that his or her work could be copied much more easily and in much higher numbers. The chapter then outlines the key concepts on which copyright is based.

scholarly journals 2. On the comparative anatomy of the thyroid gland

1851 ◽  
Vol 5 ◽  
pp. 515-515
Keyword(s):  
Thyroid Gland ◽  
Comparative Anatomy ◽  
The Other ◽  
Other Hand ◽  
Uniform Law ◽  
The One

The author, considering that the careful dissections of Meckel . and Cuvier have fully established the universal existence of a thyroid gland in the whole of the class Mammalia, proceeds to consider the comparative anatomy of this organ in the remaining classes of vertebrated animals. His dissections of birds have included all the orders, and, in most instances, several families from each : he has never failed to find in them a thyroid gland, and, with the aid of the microscope, to recognise its peculiar structure; he presumes, there­fore, that it is universally present in that class of animals. He has also detected the presence of this organ in reptiles of every order; although generally either wholly overlooked by anatomists, or mis­taken for the thymus. Descriptions are here given of its appearance, position and structure in different families of Chelonia, Sauria, Ophidia and Batrachia. In the class of Fishes, it is by no means universally or even generally present. The author has found it in the carp, anableps, pike, exocetus, cod, haddock, whiting, eel, stur­geon, callorhynchus, shark and skate, and perhaps in the lamprey. On the other hand, it appears to be absent in the perch, mullet, gurnard, mackerel, tench, salmon, trout, herring, plaice, halibut, turbot, sole, cyclopterus, gymnotus and balistes. The general conclusion which the author deduces from his re­searches is, that the distribution of the thyroid gland is regulated by a simple and uniform law ; being dependent on the existence or non­existence of another organ with which its presence alternates, and which, in many fishes, assumes the form of a minute supplementary gill, the vessels of which communicate, on the one hand, with the systemic veins about the base of the cranium, and on the other, by a single long trunk with the first branchial vein.

scholarly journals Contribution to identify the causal gents of Dutch elm disease in the Czech Republic

2008 ◽  
Vol 43 (No. 4) ◽  
pp. 142-145 ◽  
Author(s):  
M. Dvořák ◽  
M. Tomšovský ◽  
L. Jankovský ◽  
D. Novotný
Keyword(s):  
Czech Republic ◽  
North America ◽  
Molecular Biology ◽  
The Other ◽  
Dutch Elm Disease ◽  
The Czech Republic ◽  
Ophiostoma Ulmi ◽  
Other Hand ◽  
Subspecies Level ◽  
First Time

This study provides new data on Dutch elm disease in the Czech Republic. <I>Ophiostoma novo-ulmi</I> is reported for the first time in the area of the Czech Republic, as well as both subspecies ssp. <I>novo-ulmi</I> (indigenous in the area of the Ukraine and Moldavia), and ssp. <I>Americana</I> indigenous in North America. The majority of the recorded strains belonged to <I>O. n.-u.</I> ssp. <I>novo-ulmi</I>, while <I>O. n.-u.</I> ssp. <I>Americana</I> and hybrids of these two subspecies were found less frequently. On the other hand, <I>Ophiostoma ulmi</I> was not found at all in the investigated samples. Identification on the subspecies level was performed by methods of molecular biology, i.e. PCR and RFLP of gene regions<I> cu</I> and <I>col1</I>.

Larval morphology and analysis of primary chaetotaxy in the genus  Suphis Aubé, 1836 (Coleoptera: Noteridae)

Zootaxa ◽  
2019 ◽  
Vol 4619 (1) ◽  
pp. 121-138 ◽  
Author(s):  
JUAN I. URCOLA ◽  
YVES ALARIE ◽  
CESAR J. BENETTI ◽  
GEORGINA RODRIGUEZ ◽  
MARIANO C. MICHAT
Keyword(s):  
Abdominal Segment ◽  
Distal Portion ◽  
The Other ◽  
Larval Morphology ◽  
Larval Instars ◽  
Ancestral Condition ◽  
Ground Plan ◽  
Other Hand ◽  
Segment Viii ◽  
First Time

The three larval instars of Suphis cimicoides Aubé, 1837 are described and illustrated, including morphometric and chaetotaxic analyses of the cephalic capsule, head appendages, legs, last abdominal segment and urogomphus. A preliminary ground plan of primary chaetotaxy for noterid larvae is presented for the first time, based on the species described herein and examination of larvae of the genera Hydrocanthus Say, 1823 and Suphisellus Crotch, 1873. This ground plan is compared with previous systems proposed for other adephagan families. Larvae of Noteridae can be distinguished from those of other families of Hydradephaga by the following combination of characters: (1) antennomere 3 with a rugged area on distal portion; (2) abdominal segment VIII with a U-shaped wavy membranous area ventrally; (3) absence of pore FRd; and (4) presence of seta AB16. Several sensilla present in noterid larvae (notably setae TR2 and TA1 and pores PAl, PAm, COd, TRb and FEb) are absent in larvae of Meruidae. On the contrary, parietal seta PA5 is present in Meruidae but absent in Noteridae. The presence of pore COc in Noteridae may indicate that this family has retained the ancestral condition found only in Carabidae. On the other hand, the absence of setae FE7, FE8, FE9 and FE10 in Noteridae is similar to the condition found in Carabidae, Gyrinidae and Meruidae. 

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