Microglial responses to ethanol exposure in a mouse model of fetal alcohol syndrome

2014 ◽  
Author(s):  
Katelin Eloyce Ahlers
Keyword(s):  
Mouse Model ◽  
Fetal Alcohol Syndrome ◽  
Ethanol Exposure ◽  
Fetal Alcohol

Differential expression of c-fos in a mouse model of fetal alcohol syndrome

2003 ◽  
Vol 189 (3) ◽  
pp. 786-789 ◽  
Author(s):  
Sarah H Poggi ◽  
Katie M Goodwin ◽  
Joanna M Hill ◽  
Douglas E Brenneman ◽  
Elisabetta Tendi ◽  
...  
Keyword(s):  
Mouse Model ◽  
Differential Expression ◽  
Fetal Alcohol Syndrome ◽  
Fetal Alcohol

Fetal alcohol syndrome and DiGeorge anomaly. Critical ethanol exposure periods for craniofacial malformations as illustrated in an animal model

1986 ◽  
Vol 25 (S2) ◽  
pp. 97-112 ◽  
Author(s):  
Kathleen K. Sulik ◽  
Malcolm C. Johnston ◽  
Paula A. Daft ◽  
William E. Russell ◽  
Deborah B. Dehart ◽  
...  
Keyword(s):  
Animal Model ◽  
Fetal Alcohol Syndrome ◽  
Ethanol Exposure ◽  
Fetal Alcohol ◽  
Craniofacial Malformations ◽  
Digeorge Anomaly

Ethanol neurobehavioural teratogenesis and the role of L-glutamate in the fetal hippocampus

1995 ◽  
Vol 73 (9) ◽  
pp. 1209-1223 ◽  
Author(s):  
James D. Reynolds ◽  
James F. Brien
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Neuronal Development ◽  
Excitatory Amino Acid ◽  
Fetal Brain ◽  
Ethanol Exposure ◽  
Prenatal Ethanol Exposure ◽  
Fetal Alcohol ◽  
Current State ◽  
Developing Neurons

The purpose of this article is to review the current state of knowledge of ethanol neurobehavioural teratogenesis and its postulated mechanisms. The review comprises an examination of ethanol teratogenesis in the human, including the fetal alcohol syndrome, and in experimental animals. Several current proposed mechanisms of ethanol neurobehavioural teratogenesis are critically assessed, including the role of acetaldehyde as the proximate metabolite of ethanol; fetal hypoxia; placental dysfunction; fetal prostaglandin metabolism; and action of ethanol on developing neurons in the fetal brain, including the hippocampus, one of ethanol's main target sites. The effect of ethanol on the release of L-glutamate, an excitatory amino acid neurotransmitter, in the fetal hippocampus is described, and the role of L-glutamate in ethanol teratogenesis involving the hippocampus is discussed. A novel mechanism for abnormal neuronal development in the fetal hippocampus produced by prenatal ethanol exposure is presented, and future experiments to test this hypothesis are proposed.Key words: ethanol neurobehavioural teratogenesis, fetal alcohol syndrome, hippocampus, L-glutamate.

Effect of gestational ethanol exposure on parvalbumin and calretinin expressing hippocampal neurons in a chick model of fetal alcohol syndrome

Alcohol ◽  
2009 ◽  
Vol 43 (2) ◽  
pp. 147-161 ◽  
Author(s):  
Audrey G. Marshall ◽  
Molly M. McCarthy ◽  
Kirk M. Brishnehan ◽  
Venugopal Rao ◽  
Lyn M. Batia ◽  
...  
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Hippocampal Neurons ◽  
Ethanol Exposure ◽  
Fetal Alcohol
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