scholarly journals The role of certain gene polymorphisms involved in the apoptotic pathways in polycythemia vera and essential thrombocytosis

2017 ◽  
Vol 26 (5) ◽  
pp. 761-765 ◽  
Author(s):  
Gurbet DOGRU ◽  
Ozlem IZCI AY ◽  
Mehmet ERDAL ◽  
Mustafa AY ◽  
Anıl TOMBAK ◽  
...  
Keyword(s):  
Polycythemia Vera ◽  
Gene Polymorphisms ◽  
Essential Thrombocytosis ◽  
Apoptotic Pathways

scholarly journals The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients

2019 ◽  
Vol 49 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Canan ALBAYRAK ◽  
Pınar TARKUN ◽  
Elif BİRTAŞ ATEŞOĞLU ◽  
Ceyla ERALDEMİR ◽  
Özgür Doğa ÖZSOY ◽  
...  
Keyword(s):  
Polycythemia Vera ◽  
Iron Metabolism ◽  
Essential Thrombocytosis

scholarly journals UCP 2 gene polymorphisms in obesity and diabetes, and the role of UCP 2 in cancer

FEBS Letters ◽  
2019 ◽  
Vol 593 (18) ◽  
pp. 2525-2534 ◽  
Author(s):  
Jinran Li ◽  
Rihua Jiang ◽  
Xianling Cong ◽  
Yunfeng Zhao
Keyword(s):  
Gene Polymorphisms ◽  
Obesity And Diabetes

scholarly journals Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 876
Author(s):  
Sara Chiappalupi ◽  
Laura Salvadori ◽  
Rosario Donato ◽  
Francesca Riuzzi ◽  
Guglielmo Sorci
Keyword(s):  
Gene Polymorphisms ◽  
Renin Angiotensin System ◽  
Molecular Target ◽  
Advanced Glycation ◽  
Angiotensin System ◽  
Major Player ◽  
Glycation End Products ◽  
End Products ◽  
And Oxidative Stress

The receptor for advanced glycation-end products (RAGE) is a multiligand receptor with a role in inflammatory and pulmonary pathologies. Hyperactivation of RAGE by its ligands has been reported to sustain inflammation and oxidative stress in common comorbidities of severe COVID-19. RAGE is essential to the deleterious effects of the renin–angiotensin system (RAS), which participates in infection and multiorgan injury in COVID-19 patients. Thus, RAGE might be a major player in severe COVID-19, and appears to be a useful therapeutic molecular target in infections by SARS-CoV-2. The role of RAGE gene polymorphisms in predisposing patients to severe COVID-19 is discussed. 

Association of TLR4 gene polymorphisms with sepsis after a burn injury: findings of the functional role of rs2737190 SNP

2021 ◽  
Author(s):  
Claudia A. Colín-Castro ◽  
Rafael Franco-Cendejas ◽  
Hector I. Rocha-González ◽  
Esteban Cruz-Arenas ◽  
Norberto Leyva-García ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Functional Role ◽  
Burn Injury ◽  
Tlr4 Gene

A Study on the Role of Estrogen Receptor Gene Polymorphisms in Female Infertility

2016 ◽  
Vol 20 (11) ◽  
pp. 692-695 ◽  
Author(s):  
Monisha Swaminathan ◽  
Vijaya Ganesh ◽  
Teena Koshy ◽  
Priyanka Venugopal ◽  
Solomon Paul ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Female Infertility ◽  
Estrogen Receptor Gene ◽  
Receptor Gene Polymorphisms

Role of Xenobiotic-Metabolizing Enzyme Gene Polymorphisms and Interactions with Environmental Factors in Susceptibility to Gastric Cancer in Kashmir Valley

2009 ◽  
Vol 40 (1-2) ◽  
pp. 26-32 ◽  
Author(s):  
Manzoor A. Malik ◽  
Rohit Upadhyay ◽  
Rama D. Mittal ◽  
Showket A. Zargar ◽  
Dinesh R. Modi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Environmental Factors ◽  
Gene Polymorphisms ◽  
Kashmir Valley ◽  
Enzyme Gene ◽  
Metabolizing Enzyme

Role of toll-like receptor 2 and 4 gene polymorphisms in the development of allergic diseases with increased IgE levels

2012 ◽  
Vol 46 (6) ◽  
pp. 379-383 ◽  
Author(s):  
N. L. Kutsenko ◽  
O. V. Izmailova ◽  
L. E. Vesnina ◽  
I. P. Kaidashev
Keyword(s):  
Gene Polymorphisms ◽  
Allergic Diseases ◽  
Toll Like Receptor ◽  
Toll Like Receptor 2
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