scholarly journals PRIMER EPISODIO PSICÓTICO Y EL CONSUMO DE CANNABIS: ¿CUÁL ES EL IMPACTO EN LA COGNICIÓN?

2021 ◽  
Author(s):  
Maria João Gonçalves ◽  
Rita André ◽  
Joana Romão ◽  
Rodrigo Saraiva ◽  
Gabriela Andrade ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
First Episode Psychosis ◽  
Cannabis Use ◽  
First Episode ◽  
Episode Psychosis

1.Objetivos: La prevalencia del trastorno por uso de cannabis (TUC) es <10% en la población general, llegando a 27,1% en la esquizofrenia. El 64% de personas con primer episodio psicótico (PEP) consumen cannabis, el 30% de los cuales presentan TUC. Los pacientes con diagnosis de PEP tienen mayor probabilidad de presentar consumo de cannabis de alta potencia (THC > 10%). Los déficits cognitivos en pacientes con esquizofrenia (con o sin consumo de cannabis) son determinantes para su funcionamiento, y parecen estar presentes desde el PEP. Revisar el conocimiento actual acerca de la asociación entre TUC y los déficits cognitivos en personas con PEP. 2.Material y métodos: Selección de artículos científicos publicados en los últimos 6 años; recerca en bases de datos utilizando la combinación de términos MeSH: “cannabis use”, “first-episode psychosis”y “cognitive impairment”. 3.Resultados y conclusiones: Los estudios desarrollados se han centrado en la relación entre el consumo de cannabis y cognición en PEP, con la evaluación de funciones neurocognitivas a registrar mayor afección en la atención, memoria verbal y funciones executivas. Sin embargo, algunos resultados han sido contradictorios debido a fatores como: heterogeneidad de cuadros clínicos (hay estudios con un enfoque en psicosis en general, incluyendo psicosis afectivas, mientras que otros se centran específicamente en esquizofrenia o PEP); El cannabis presenta tetrahidrocanabinol (THC) y canabidiol (CBD) que pueden tener efetos opuestos en la cognición. El THC tiene un efeto prejudicial y hay evidencia de que el CBD puede mejorar la cognición. Son necesarios nuevos estudios para evaluar la asociación entre el consumo de cannabis y disfunción cognitiva. Sin embargo, las muestras deben tener un tamaño significativo, uniformidad diagnostica y deben ser controlados los fatores confundentes en las variables evaluadas. Así, deben ser estudiadas las características diferenciales entre cuadros clínicos aisladamente para que los resultados pueden ser verificados y replicados.

Childhood symptoms of inattention–hyperactivity predict cannabis use in first episode psychosis

2011 ◽  
Vol 132 (2-3) ◽  
pp. 171-176 ◽  
Author(s):  
Clifford M. Cassidy ◽  
Ridha Joober ◽  
Suzanne King ◽  
Ashok K. Malla
Keyword(s):  
First Episode Psychosis ◽  
Cannabis Use ◽  
First Episode ◽  
Episode Psychosis

scholarly journals S101. CLINICAL FACTORS ASSOCIATED WITH CANNABIS USE IN A CHILEAN SAMPLE OF FIRST EPISODE PSYCHOSIS PATIENTS

2018 ◽  
Vol 44 (suppl_1) ◽  
pp. S364-S364
Author(s):  
Barbara Iruretagoyena ◽  
Nicolas Crossley ◽  
Alfonso Gonzalez-Valderrama ◽  
Cristian Mena ◽  
Carmen Castañeda ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
Cannabis Use ◽  
First Episode ◽  
Clinical Factors ◽  
Factors Associated ◽  
Episode Psychosis

Continued Cannabis Use and Outcome in First-Episode Psychosis

2012 ◽  
Vol 73 (05) ◽  
pp. 632-638 ◽  
Author(s):  
Gunnar Faber ◽  
Henderikus G. O. M. Smid ◽  
Arthur R. Van Gool ◽  
Lex Wunderink ◽  
Robert J. van den Bosch ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
Cannabis Use ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Impact of first episode psychosis treatment on heavy cannabis use: Secondary analysis on RAISE-ETP study

2019 ◽  
Vol 211 ◽  
pp. 86-87 ◽  
Author(s):  
Karl C. Alcover ◽  
Oladunni Oluwoye ◽  
Liat Kriegel ◽  
Sterling McPherson ◽  
Michael G. McDonell
Keyword(s):  
Secondary Analysis ◽  
First Episode Psychosis ◽  
Cannabis Use ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Cannabis use and first-episode psychosis: relationship with manic and psychotic symptoms, and with age at presentation

2013 ◽  
Vol 44 (3) ◽  
pp. 499-506 ◽  
Author(s):  
J. M. Stone ◽  
H. L. Fisher ◽  
B. Major ◽  
B. Chisholm ◽  
J. Woolley ◽  
...  
Keyword(s):  
Longitudinal Design ◽  
First Episode Psychosis ◽  
Cannabis Use ◽  
Daily Functioning ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Time Points ◽  
Manic Symptoms ◽  
Episode Psychosis ◽  
Early Intervention In Psychosis

BackgroundCannabis use has been reported to be associated with an earlier onset of symptoms in patients with first-episode psychosis, and a worse outcome in those who continue to take cannabis. In general, studies have concentrated on symptoms of psychosis rather than mania. In this study, using a longitudinal design in a large naturalistic cohort of patients with first-episode psychosis, we investigated the relationship between cannabis use, age of presentation to services, daily functioning, and positive, negative and manic symptoms.MethodClinical data on 502 patients with first-episode psychosis were collected using the MiData audit database from seven London-based Early Intervention in psychosis teams. Individuals were assessed at two time points – at entry to the service and after 1 year. On each occasion, the Positive and Negative Syndrome Scale, Young Mania Rating Scale and Global Assessment of Functioning Scale disability subscale were rated. At both time points, the use of cannabis and other drugs of abuse in the 6 months preceding each assessment was recorded.ResultsLevel of cannabis use was associated with a younger age at presentation, and manic symptoms and conceptual disorganization, but not with delusions, hallucinations, negative symptoms or daily functioning. Cannabis users who reduced or stopped their use following contact with services had the greatest improvement in symptoms at 1 year compared with continued users and non-users. Continued users remained more symptomatic than non-users at follow-up.ConclusionsEffective interventions for reducing cannabis use may yield significant health benefits for patients with first-episode psychosis.

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