NUMERICAL SIMULATIONS OF MATHEMATICAL MODELS FOR CHEMO-IMMUNOTHERAPY: DETERMINATION OF IMMUNE SYSTEM COMPONENTS MOST CRITICAL FOR TUMOUR ERADICATION

2021 ◽  
Vol 129 (1) ◽  
pp. 81-112
Author(s):  
Hammed A. Ejalonibu ◽  
Joseph Malinzi
Keyword(s):  
Immune System ◽  
Mathematical Models ◽  
Numerical Simulations ◽  
System Components

AGGLUTINATION INHIBITION REACTIONS FOR THE DETERMINATION OF GONADOTROPHINS

1969 ◽  
Vol 62 (1_Suppl) ◽  
pp. S95-S112 ◽  
Author(s):  
A. H. W. M. Schuurs
Keyword(s):  
Immune System ◽  
Quantitative Determination ◽  
Haemagglutination Inhibition ◽  
Latex Agglutination ◽  
Literature Survey ◽  
New Method ◽  
Test Fluid ◽  
Main Application ◽  
Test Systems

ABSTRACT Various techniques for sensitising erythrocytes and latex particles with gonadotrophins, particularly with HCG, are described. The haemagglutination inhibition reactions are generally interpreted by means of »erythrocyte settling patterns«. By a new method of evaluating these patterns a relatively precise quantitative determination is possible. Latex agglutination inhibition reactions on slides are particularly suitable as rapid qualitative tests. In cases where the maximum attainable sensitivity of the agglutination inhibition tests is insufficient, e. g. for determining LH concentrations in urine, the hormone in the test fluid has to be concentrated or extracted. An alternative method is a modified haemagglutination inhibition test for large volumes which is applicable to unconcentrated urine. Due to non-specific inhibitions the above-mentioned tests cannot be applied to unprocessed serum. Agglutination inhibition tests with HCG are already well advanced, pregnancy diagnosis being their main application. Now that highly purified HCG is available, a satisfactory specificity for these tests can be attained. If the immune system for HCG is used for estimating LH, it has to meet additional specificity requirements. Furthermore, the measure of cross-reaction and the choice of standard merit special attention. Finally, a literature survey is given of test systems in which LH and FSH were used as antigens.

DETERMINATION OF THE JUICE EVAPORATION MATHEMATICAL MODELS EFFICIENCY FOR AUTOMATED PROCESS CONTROL SYSTEMS

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
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Keyword(s):  
Process Control ◽  
Mathematical Models ◽  
Control Systems ◽  
Process Control Systems ◽  
Automated Process

scholarly journals Effect of data quality on estimates of farm infectiousness trends in the UK 2001 foot-and-mouth disease epidemic

2006 ◽  
Vol 4 (13) ◽  
pp. 235-241 ◽  
Author(s):  
Nicholas J Savill ◽  
Darren J Shaw ◽  
Rob Deardon ◽  
Michael J Tildesley ◽  
Matthew J Keeling ◽  
...  
Keyword(s):  
Mathematical Models ◽  
Data Quality ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Inaccurate Data ◽  
Foot And Mouth ◽  
The Uk ◽  
Parameter Values

Most of the mathematical models that were developed to study the UK 2001 foot-and-mouth disease epidemic assumed that the infectiousness of infected premises was constant over their infectious periods. However, there is some controversy over whether this assumption is appropriate. Uncertainty about which farm infected which in 2001 means that the only method to determine if there were trends in farm infectiousness is the fitting of mechanistic mathematical models to the epidemic data. The parameter values that are estimated using this technique, however, may be influenced by missing and inaccurate data. In particular to the UK 2001 epidemic, this includes unreported infectives, inaccurate farm infection dates and unknown farm latent periods. Here, we show that such data degradation prevents successful determination of trends in farm infectiousness.

Determination of HE4-mediated roles in tumor immune system modulation in Epithelial Ovarian Cancer (EOC)

2015 ◽  
Vol 139 (3) ◽  
pp. 591
Author(s):  
Anze Urh ◽  
Nicole Romano ◽  
KyuKwang Kim ◽  
Jennifer Ribeiro ◽  
Christina Raker ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Immune System ◽  
Epithelial Ovarian Cancer ◽  
Immune System Modulation

Numerical simulations of the soft X-ray signals for determination of radial locations of the magnetic islands in the STOR-M tokamak

2011 ◽  
Vol 166 (10) ◽  
pp. 765-773 ◽  
Author(s):  
M. Dreval ◽  
C. Xiao ◽  
A. Hirose
Keyword(s):  
Numerical Simulations ◽  
Magnetic Islands ◽  
X Ray

scholarly journals Determination of sialic acids in immune system cells (coelomocytes) of sea urchin, Paracentrotus lividus, using capillary LC-ESI-MS/MS

2014 ◽  
Vol 36 (1) ◽  
pp. 181-186 ◽  
Author(s):  
Savaş İzzetoğlu ◽  
Umut Şahar ◽  
Ecem Şener ◽  
Remziye Deveci
Keyword(s):  
Immune System ◽  
Sea Urchin ◽  
Paracentrotus Lividus ◽  
Sialic Acids ◽  
Esi Ms

scholarly journals Determination of parameters for Cauchy’s problem for systems of ODEs with application to biological modelling

BIOMATH ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 1604231
Author(s):  
A.N. Pete ◽  
Peter Mathye ◽  
Igor Fedotov ◽  
Michael Shatalov
Keyword(s):  
Experimental Data ◽  
Mathematical Models ◽  
Least Squares ◽  
Numerical Method ◽  
Least Squares Method ◽  
Algebraic Equations ◽  
Systems Of Odes ◽  
Determination Of Parameters ◽  
Biological Modelling

An inverse numerical method that estimate parameters of dynamic mathematical models given some information about unknown trajectories at some time is applied to examples taken from Biology and Ecology. The method consisting of determining an over-determined system of algebraic equations using experimental data. The solution of the over-determined system is then obtained using, for example the least-squares method. To illustrate the effectiveness of the method an analysis of examples and corresponding numerical example are presented.

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