scholarly journals Evaluation of hormonal balance indicators in men with arterial hypertension in various types of left ventricular remodeling

2016 ◽  
Vol 97 (3) ◽  
pp. 323-327
Author(s):  
N N Fedorova ◽  
M M Habibulina
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Blood Serum ◽  
Ventricular Hypertrophy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Testosterone Levels ◽  
Concentric Left Ventricular Hypertrophy ◽  
Hormonal Balance ◽  
Eccentric Hypertrophy

Aim. To evaluate features of the hormonal balance in men with hypertension with different types of left ventricular geometry.Methods. The study included 63 men (mean age 49.74±4.91 years) with II degree hypertension (the disease duration 6.03±3.64 years). In all patients the level of testosterone, estradiol, prolactin, thyroid-stimulating hormone in blood serum were determined and echocardiography was performed, which was done on the expert class machine PHILIPS iE33 (Netherlands).Results.. According to echocardiographic examination data concentric hypertrophy prevailed in the left ventricular hypertrophy structure - 33 (52.38%) patients, eccentric hypertrophy occured in 18 (28.57%), concentric remodeling - in 12 (19.04%) patients. When analyzing the hormonal profile of patients a significant difference in testosterone levels in patients with various types of the left ventricular remodeling was revealed. In the concentric left ventricular hypertrophy, testosterone levels were lowest, and in some patients were beyond the lower limit of the normal range. Estradiol level exceeded the reference range values in men with concentric type of hypertrophy. The estradiol content in the group of men with concentric left ventricular remodeling was significantly higher than in patients with eccentric hypertrophy (pConclusion. In patients with hypertension, concentric left ventricular hypertrophy (as compared with eccentric hypertrophy and concentric remodeling) occurs more often, it is accompanied by a decrease in total testosterone level in blood serum; timely correction of early androgen deficiency will allow to reduce the risk of cardiovascular complications.

scholarly journals Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff

2017 ◽  
Vol 47 (9) ◽  
Author(s):  
Guilherme Augusto Minozzo ◽  
Simone Tostes de Oliveira Stedile ◽  
Marlos Gonçalves Sousa
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Aortic Stenosis ◽  
Ventricular Hypertrophy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Skin Lesions ◽  
Left Ventricular ◽  
The Body ◽  
Congenital Aortic Stenosis ◽  
Eccentric Hypertrophy

ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.

scholarly journals 5-YEAR DYNAMICS OF FEATURES OF LEFT VENTRICULAR GEOMETRY IN PATIENTS WITH ISCHEMIC HEART DISEASE, DEPENDING ON TREATMENT TACTICS

2019 ◽  
Vol 19 (3) ◽  
pp. 17-21
Author(s):  
R.R. Guta ◽  
N.S. Beck ◽  
O.M. Radchenko
Keyword(s):  
Heart Disease ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Comparison Group ◽  
Myocardial Revascularization ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry ◽  
Concentric Left Ventricular Hypertrophy ◽  
Eccentric Hypertrophy

Introduction. For a patient with coronary heart disease, recovery from myocardial revascularization is a complex process. Cardiac remodeling involves, after myocardial infarction, hypertrophy and dilation, resulting in impaired systolic-diastolic cardiac function, which is an additional risk factor for events. Prospective studies have shown a relationship between left ventricular size and the risk of cardiovascular events. Given this, there was a need to conduct our research. Purpose: To determine the prevalence of types of left ventricular geometry in patients with coronary heart disease, post-infarction cardiosclerosis, depending on therapeutic tactics: revascularization or conservative therapy for 60 months. Material and Methods: We examined 101 patients aged 58.6±4.2 years after myocardial revascularization (n = 71) and with conservative treatment only (n = 30), in whom the dynamics of echocardiographic parameters of the heart were evaluated for 5 years. The values ​​of remodeling myocardial mass index of the left ventricle and the relative thickness of the left ventricle were determined. Results and Discussion. At baseline, patients with concentric left ventricular hypertrophy (50.0%) and concentric remodeling (24.1%) predominated in the main group. Normal geometry in 14.8% and eccentric left ventricular hypertrophy were observed in 11.1%. In the comparison group, eccentric hypertrophy and concentric left ventricular remodeling were most commonly observed, 29.6% each, slightly less than 25.9% concentric hypertrophy, and the least was normal geometry (14.8%). After 60 months, patients with both groups did not experience normal left ventricular geometry and concentric remodeling. The concentric type (80.0%) was predominant in the main group, and the eccentric type (55.6%) in the comparison group. Conclusions. In patients with ischemic heart disease, postinfarction cardiosclerosis progresses in 5 year follow-up myocardial hypertrophy regardless of treatment. After revascularization, concentric left ventricular hypertrophy develops more often, whereas under conservative treatment, left ventricular eccentric hypertrophy is combined with systolic dysfunction and left atrial dilatation. After revascularization, an increase in the index was associated with an increase not only in body weight but also in changes in lipid profile and diastolic hypertension.

scholarly journals HYPERTENSION IN THYROTOXICOSIS AND ITS IMPACT ON LEFT VENTRICULAR HYPERTROPHY

2013 ◽  
Vol 19 (3) ◽  
pp. 237-241 ◽  
Author(s):  
A. Yu. Babenko ◽  
E. N. Grineva ◽  
V. N. Solntsev
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Systolic Hypertension ◽  
Ventricular Hypertrophy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
High Rate ◽  
Cardiovascular Prognosis

Objective. We present the results of the study assessing the frequency and character of hypertension in thyrotoxicosis, and its impact on left ventricular remodeling and cardiovascular prognosis.Results and conclusions. Our data demonstrated that hypertension, and predominantly systolic hypertension, is highly prevalent in thyrotoxicosis and affects left ventricular remodeling. All normotensive patients developed only eccentric left ventricular hypertrophy (LVH). The prevalence of LVH, and of its concentric forms increases with the elevation of blood pressure. Concentric LVH is associated with the high rate of atrial fi brillation and heart failure.

scholarly journals The Peculiarity of Left Ventricular Remodeling in Patients with Hypertension Developing Acute Myocardial Infarction

2021 ◽  
Vol 6 (1) ◽  
pp. 153-159
Author(s):  
I. M. Fushtey ◽  
◽  
E. V. Sid’ ◽  
V. О. Ivashchuk
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
St Segment Elevation

The purpose of the study was to determine the peculiarity of left ventricular remodeling among patients with hypertension developing acute myocardial infarction. Material and methods. The results of the study are based on the data of a comprehensive examination of 477 patients with coronary artery disease: 280 patients with STEMI (ST-segment elevation myocardial infarction), 91 patients with NSTEMI (non ST-segment elevation myocardial infarction) and the control group consisted of 76 patients with exertional angina (II and III functional class for 38 people). The examination of patients was carried out in the period from 2015 to January 2018 on the basis of the Regional Medical Center for Cardiovascular Diseases of the Zaporozhye Regional Council. All patients (n=477) were comparable in age, social status and gender. The proportion of patients with hypertension was comparable between the groups and amounted to 255 (91.1%) patients with STEMI, 86 (94.5%) with NSTEMI, and 71 (93.4%) patients with stable coronary artery disease. Results and discussion. The development of left ventricular hypertrophy is a long-term process in hypertensive patients. At first, there is a change in the geometry of the left ventricle, since during systole the ventricle tends to take a spherical shape. Further, dilatation of cavities, hypertrophy and an increase in the mass of the left ventricular myocardium, replacement of the myocardium with fibrous tissue develop. Whereas in patients with acute myocardial infarction, due to acute myocardial ischemia, thickening of the myocardial wall is associated with interstitial edema occurs rather quickly. These important factors make it difficult to compare different studies and to reliably identify patients with true left ventricular hypertrophy. Therefore, left ventricular myocardium mass index should be determined as early as possible in patients with hypertension after the development of acute myocardial infarction, in order to interpret the obtained data. Сonclusion. Ischemic heart disease is often associated with essential hypertension, more than 90% of patients with acute myocardial infarction developed essential hypertension. It was determined that eccentric and concentric left ventricular hypertrophy prevailed among those examined on the first day of hospitalization and was due to the presence of hypertension

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