On the issue of pulmonary embolism

Abstracts. Review of Obstetric and Gynecological literature: Russian.A.A. Maksimov. On the issue of pulmonary embolism . (Journal. Russian. General. Protection. Nar. Health. 1897,. No. 11, p. 647).Schmorl, who discovered pulmonary artery embolism with cells later, identified this phenomenon as the cause of eclampsia in pregnant women. Lubarsch considered embolism as a consequence of all sorts of seizures in pregnant women. Kasyanov, who found embolism in all pregnant women, suggested that this is a physiological phenomenon that occurs during every pregnancy. The author studied the lungs in 40 pregnant rabbits and was convinced that, under normal conditions, the rabbit does not have pulmonary embolism with shorts after.

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Clinical importance of the distribution of pulmonary artery embolism in acute pulmonary embolism

Journal of International Medical Research ◽

10.1177/03000605211004769 ◽

2021 ◽

Vol 49 (4) ◽

pp. 030006052110047

Author(s):

Yunqiang Nie ◽

Li Sun ◽

Wei Long ◽

Xin LV ◽

Cuiyun Li ◽

...

Keyword(s):

Pulmonary Embolism ◽

Pulmonary Artery ◽

Right Ventricular ◽

Mixed Type ◽

Acute Pulmonary Embolism ◽

Disease Duration ◽

Clinical Importance ◽

Artery Embolism ◽

Pulmonary Embolisms ◽

Pulmonary Artery Embolism

Objective To explore the clinical importance of the distribution of pulmonary artery embolism in acute pulmonary embolism (APE). Methods Sixty-four patients with APE were classified into mixed-type and distal-type pulmonary embolism groups. Their right ventricular systolic pressure (RVSP) and disease duration were recorded, and the diameter of their right ventricles was measured by ultrasound. The computed tomography angiographic clot load was determined as a Mastora score. Results Patients with distal-type pulmonary embolisms had significantly lower RVSPs (44.92 ± 17.04 vs 55.69 ± 17.66 mmHg), and significantly smaller right ventricular diameters (21.08 ± 3.06 vs 23.37 ± 3.48 mm) than those with mixed-type pulmonary embolisms. Additionally, disease duration was significantly longer in patients with distal-type pulmonary embolisms (14.33 ± 11.57 vs 8.10 ± 7.10 days), and they had significantly lower Mastora scores (20.91% ± 18.92% vs 43.96% ± 18.30%) than patients with mixed-type pulmonary embolisms. After treatment, RVSPs decreased significantly in patients with both distal-type and mixed-type pulmonary embolisms. Right ventricle diameters also decreased significantly in patients with mixed-type pulmonary embolisms after treatment. Conclusion Patients with mixed-type pulmonary embolisms are significantly more susceptible to pulmonary hypertension, enlarged right ventricular diameters, and shorter durations of disease than those with distal-type pulmonary embolisms. The distribution of pulmonary artery embolism in APE can provide a clinical reference.

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Present aspects of thrombolytic therapy of pulmonary artery thromboembolism

Clinical Medicine (Russian Journal) ◽

10.30629/0023-2149-2021-99-1-6-14 ◽

2021 ◽

Vol 99 (1) ◽

pp. 6-14

Author(s):

Y. V. Ovchinnikov ◽

M. V. Zelenov ◽

V. S. Polovinka ◽

E. V. Kryukov

Keyword(s):

Pulmonary Embolism ◽

High Risk ◽

Pulmonary Artery ◽

Thrombolytic Therapy ◽

Pulmonary Blood Flow ◽

Pulmonary Thromboembolism ◽

Comparative Efficiency ◽

Artery Embolism ◽

Pulmonary Arterial ◽

Pulmonary Artery Embolism

The concept of high-risk pulmonary artery embolism determines that verification of the occlusion of the pulmonary arterial bed requires urgent restoration of pulmonary blood flow in such patients. Thrombolytic therapy is currently recognized as the main treatment for pulmonary artery thromboembolism. It can save patients’ lives, prevent the development of chronic post embolic pulmonary hypertension and thromboembolism recurrence. The literature review presents thrombolytic medications used in the treatment of pulmonary thromboembolism, describes indications for thrombolytic therapy, comparative efficiency and safety of various thrombolytics. The main complications of thrombolytic therapy are described and the issues of increasing its safety are raised. Criteria for the success of thrombolysis are early diagnosis, accurate risk stratification, and adequate use of reperfusion agents in patients with high-risk or transitionally high-risk of pulmonary embolism.

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A case of pulmonary embolism in a fracture of both lower extremities

Kazan medical journal ◽

10.17816/kazmj47059 ◽

1903 ◽

Vol 3 (3-4) ◽

pp. 155-155

Author(s):

N. N. Smirnov

Keyword(s):

Pulmonary Embolism ◽

Pulmonary Artery ◽

Venous Thrombosis ◽

Clinical Picture ◽

Statistical Data ◽

Lower Extremities ◽

Lower Leg ◽

Unexpected Death ◽

Artery Embolism ◽

Pulmonary Artery Embolism

In the case observed by the author, the patient had an unexpected death (within 1/2 hour with the onset of cardiac paralysis) in the period of recovery 3 weeks after the fracture of the shin bones (2-sided). Autopsy revealed thrombosis of the vein of the lower leg and embolism of the pulmonary artery, -Embolism on the basis of venous thrombosis, according to statistical data, is rather rare. In total, there are currently 37 cases of proven embolism and 15 cases. 70% of this number should be attributed to after fractures. Depending on the size of the embolus and the place of the drift, it causes a clinical picture of varying severity and outcome.

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Prediction of Mortality Associated with Cardiac and Radiological Findings in Patients with Pulmonary Embolism

Journal Of Cardiovascular Emergencies ◽

10.2478/jce-2020-0020 ◽

2020 ◽

Vol 6 (4) ◽

pp. 84-90

Author(s):

Sema Avci ◽

Gokhan Perincek ◽

Muammer Karakayali

Keyword(s):

Pulmonary Embolism ◽

Pulmonary Artery ◽

Complete Blood Count ◽

Clinical Signs ◽

Axis Deviation ◽

Arterial Blood ◽

Prediction Of Mortality ◽

Artery Embolism ◽

Right Pulmonary Artery ◽

Pulmonary Artery Embolism

AbstractBackground: In this study, we aimed to compare echocardiography, electrocardiography (ECG) abnormalities, Doppler ultrasonography (USG), and computed tomography pulmonary angiography (CTPA) results in predicting 3-month mortality in patients with acute pulmonary embolism (PE).Methods: This retrospective cohort study included 124 patients (72 females, 52 males) with acute PE. Demographics, symptoms, clinical signs, comorbidities, history of surgery, arterial blood gas, liver-renal functions, complete blood count, echocardiography, ECG, Doppler USG, and CTPA results, as well as 3-month mortality were recorded.Results: pH (z = –2.623; p <0.01), hemoglobin (z = –3.112; p <0.01), and oxygen saturation (z = –2.165; p <0. 01) were significantly higher in survivors. White blood cell (z = –2.703; p <0.01), blood urea nitrogen (z = –3.840; p <0.01), creatinine (z = –3.200; p <0.01), respiratory rate (z = –2.759; p <0.01), and heart rate (z = –2.313; p <0.01) were significantly higher in non-survivors. Nonspecific ST changes (AUC 0.52, 95% CI 0.43–0.61), p pulmonale (AUC 0.52, 95% CI 0.43–0.61), normal axis (AUC 0.61), right axis deviation (AUC 0.56), right ventricle strain pattern (AUC 0.59), and right pulmonary artery embolism (AUC 0.54) on CTPA showed the highest mortality prediction.Conclusions: Nonspecific ST changes, p pulmonale, normal axis and right axis deviation in ECG, RV strain in echocardiography, and right pulmonary artery embolism on CTPA are associated with a higher mortality in patients with PE.

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