scholarly journals The influence of diffuse toxic goiter on the course and outcome of pregnancy

2012 ◽  
Vol 61 (4) ◽  
pp. 67-74
Author(s):  
Yulia Sergeevna Lovkova ◽  
Vladimir Vsevolodovich Potin ◽  
Natalya Nikolaevna Tkachenko ◽  
Elisaveta Valeryevna Shelayeva ◽  
Tachira Timurovna Musaeva

We have studied peculiarities of pregnancy, delivery and neonatal thyroid status in 58 women with diffuse toxic goiter. During pregnancy patients received thyreostatic therapy (imidazole and thiouracil derivates). Examination consisted of assessment of levels of free thyroxin, TSH, autoantibodies to TSH-receptors and autoantibodies to thyroperoxidasis in the blood of pregnant women and in umbilical cord blood. The group of comparison consisted of 58 women without thyroid pathology and 111 women with autoimmune thyroiditis. In women with diffuse toxic goiter preeclampsia, chronic placental insufficiency, preterm rupture of membranes, fetal hypotrophy and hypoxia were observed more frequently. 17 % of newborns of mothers with diffuse toxic goiter had subclinical hyperthyroidism and 54% of newborns — subclinical hypothyroidism, depending of transplacental pass of thyreostatic medications

2017 ◽  
Vol 66 (3) ◽  
pp. 89-96 ◽  
Author(s):  
Julia S. Lovkova ◽  
Vladimir V. Potin ◽  
Natalya N. Tkachenko ◽  
Elisaveta V. Shelayeva

We have studied an influence of diffuse toxic goiter on the flow and outcome pregnancy. 67 pregnant women with diffuse toxic goiter were examined. The group of comparison consisted of 38 pregnant women without thyroid pathology. The levels of free thyroxin, TSH, autoantibodies to TSH-receptors and autoantibodies to thyreoperoxidasis in the blood of pregnant women and umbilical cord blood and ultrasound of the thyroid gland of newborns were analyze. Pregnancy and childbirth of the women with unresolved thyrotoxicosis were more complicated by the threat of termination of pregnancy, preeclampsia, chronic placental insufficiency, preterm rupture of membranes, fetal hypotrophy and hypoxia. A high incidence of subclinical hypothyroidism (more 50%) in newborns is associated with the transplacental pass thyreostatic drugs. Subclinical hyperthyroidism in 17% of newborns should be associated with the transplacental transition from the mother to the fetus of autoantibodies to TSH-receptors.


2008 ◽  
Vol 215 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Darko Grujicic ◽  
Olivera Miloševic-Djordjevic ◽  
Slobodan Arsenijevic ◽  
Dragoslav Marinkovic

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Sameer Timilsina ◽  
Sirisa Karki ◽  
Aajeevan Gautam ◽  
Pujan Bhusal ◽  
Gita Paudel ◽  
...  

2010 ◽  
Vol 1 ◽  
pp. S60
Author(s):  
Leandro DeOliveira ◽  
Marcos Cenedeze ◽  
Rafael Larocca ◽  
Nelson Sass ◽  
Niels Olsen Câmara

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Yanmei Sun ◽  
Pingping Zhang ◽  
Ning Zhang ◽  
Limin Rong ◽  
Xiaoping Yu ◽  
...  

1989 ◽  
Vol 27 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Ralph J. Lellé ◽  
Eberhard Henkel ◽  
Dieter Leinemann ◽  
Klaus Goeschen

2008 ◽  
Vol 34 (1) ◽  
pp. 12-19
Author(s):  
Byung-Mi Kim ◽  
Dae-Seon Kim ◽  
Jong-Hwa Lee ◽  
Hye-Sook Park ◽  
Young-Ju Kim ◽  
...  

Author(s):  
Kyung Eun Lee ◽  
Young Seoub Hong ◽  
Dae Seon Kim ◽  
Myoung Seok Han ◽  
Byeng Chul Yu ◽  
...  

2010 ◽  
Vol 92 (6) ◽  
pp. 1416-1422 ◽  
Author(s):  
Rima Obeid ◽  
Mariz Kasoha ◽  
Susanne H Kirsch ◽  
Winfried Munz ◽  
Wolfgang Herrmann

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