scholarly journals Further research in the area of the central endings of the X-th pair of cranial nerves

2020 ◽  
Vol VI (2) ◽  
pp. 155-168
Author(s):  
V. P. Osipov
Keyword(s):  
Vagus Nerve ◽  
Medulla Oblongata ◽  
Cranial Nerves ◽  
Vagus Nerves ◽  
The Way

In 1896, I published the research of the central endings of the vagus nerve. Continuing with the study in the indicated direction, I received, in addition to confirming the results of the first study, some results that were not devoid of interest; These results were not new for me, because on the microscopic preparations that served as materials for the first work, there are corresponding changes in the area of ​​the central endings of the vagus nerve; on the contrary, further research was undertaken by me with the aim of checking the constancy of some changes in the medulla oblongata, advancing every step of the way behind the overwhelming vagus nerves. Thus, the present work is, as it were, an addition to the first one, containing the results of research that were not included in the first work.

scholarly journals Research of the central beginnings and endings of the accessory nerve (N. accessorius Willisii)

2020 ◽  
Vol VI (1) ◽  
pp. 118-138
Author(s):  
V. P. Osipov
Keyword(s):  
Spinal Cord ◽  
Vagus Nerve ◽  
Medulla Oblongata ◽  
Artificial Respiration ◽  
Cranial Nerves ◽  
Nerve Trunk ◽  
Accessory Nerve ◽  
Common Trunk ◽  
First Case ◽  
The Common

Starting at the end of the 16th century (Volcherus Goiter - 1573) and up to our time, about sixty authors studied the accessory nerve, partly dedicating special work to it, partly giving their views on the course and ending of this nerve in the textbooks of anatomy and histology published by them. Such persistence in the study of the accessory nerve is explained by the duality of its central beginnings and endings, that is, its origin both from the oblong and from the spinal cord. Already with a rough anatomical examination, it is clear that part of the roots emerging from the lower part of the medulla oblongata, not reaching the foramen jugulare of the skull, joins the nerve trunk, which runs along the lateral surface of the spinal cord and is formed by the connection of the roots emerging from the lateral brain. This common nerve trunk, emerging from the cranial cavity through the foram. jugulare and consisting of N. accessorius vagi and N. accessorius spinalis, received the name N. accessorius Willissi, named after Thomasa Willisa (1682) who described it. After exiting the foramen jugulare, the nerve gives a thin v-point (ramus internus according to Heihendainy) to the plexus ganglioformis n. vagi, and another, thick branch, is sent to the muscles (m. sternocleido-mastoideus). Thus, without the help of a microscope, a close connection between the XI and X pairs of cranial nerves is visible. To this, it must be added that the roots of the XI nerve, emerging from the lower sections of the medulla oblongata, produce the impression of the lower roots of the X nerve, and only their entry into the common trunk of the accessory nerve forces them to be referred to it. Heidenhain, using a physiological method, proved the connection between the accessory nerve and the vagus: he pulled out the accessory nerve in rabbits on the neck and after a few days after the operation did not receive the usual slowing of heartbeats with irritation of the vagus nerve; From this, the author concludes that the retarding heartbeat fibers of the vagus nerve receive an additional one through the ramus internus. Further, the author comes to the conclusion that the fibers of the accessory nerve, which delay the heartbeat, originate from the medulla oblongata. To confirm this view, Heidenhain cites experiments in which he, during artificial respiration of an animal, provided a cut of the medulla oblongata at the apex of the pen (calamus scriptorius) and below; with a slowdown of artificial respiration in the first case, a slowdown of the heartbeat was obtained, and in the second it did not work. Finally, in rabbits, after the accessory nerve was torn out, the laryngeal paralysis was as clearly expressed as after the X nerve was cut; food got into the respiratory tract, and the animals died from pneumonia, which usually began with the upper lobes).

Neurophysiological Intraoperative Monitoring of the Glossopharyngeal Nerve: Technical Case Report

2008 ◽  
Vol 63 (suppl_4) ◽  
pp. ONSE277-ONSE278 ◽  
Author(s):  
Aatif M. Husain ◽  
David R. Wright ◽  
Bret W. Stolp ◽  
Allan H. Friedman ◽  
John C. Keifer
Keyword(s):  
Vagus Nerve ◽  
Intraoperative Monitoring ◽  
Cranial Nerves ◽  
Glossopharyngeal Nerve ◽  
Vagus Nerves ◽  
Nerve Monitoring ◽  
Adhesive Surface ◽  
Pharyngeal Muscles ◽  
Swallowing Difficulty ◽  
Lower Cranial Nerves

Abstract Objective: Neurophysiological intraoperative monitoring of the glossopharyngeal nerve has been performed only with needle electrodes inserted into the pharyngeal muscles or soft palate. We describe a noninvasive method of monitoring this cranial nerve. Methods: A 30-year-old man who presented with headache, as well as speech and swallowing difficulty, underwent surgical resection of a right vagus nerve schwannoma. Neurophysiological intraoperative monitoring of multiple lower cranial nerves, including the glossopharyngeal and vagus nerves, was performed. Results: The glossopharyngeal nerve was monitored with an adhesive surface electrode mounted on the cuff of a laryngeal mask airway, and the vagus nerve was monitored with a similar electrode mounted on the endotracheal tube. Successful monitoring allowed separation of the glossopharyngeal nerve from the tumor, and there was no postoperative swallowing deficit. Conclusion: Monitoring of the glossopharyngeal nerve with surface electrodes is possible and reliable, but it must be combined with vagus nerve monitoring.

Microsurgical resection of a glioblastoma multiforme of the medulla oblongata with intraoperative subcortical stimulation and mapping

2019 ◽  
Vol 1 (2) ◽  
pp. V1
Author(s):  
Sima Sayyahmelli ◽  
Jian Ruan ◽  
Bryan Wheeler ◽  
Mustafa K. Başkaya
Keyword(s):  
Glioblastoma Multiforme ◽  
Surgical Resection ◽  
Medulla Oblongata ◽  
Cranial Nerves ◽  
The Body ◽  
Fine Motor ◽  
Surgical Video ◽  
Inferior Aspect ◽  
Hyperintense Signal ◽  
Microsurgical Resection

Primary glioblastoma multiforme tumors of the medulla oblongata are rare, especially in the adult population. Perhaps due to this rarity, we are not aware of any previous reports addressing the resection of these tumors or their clinical outcomes.In this surgical video, we present a 43-year-old man with a 1-month history of left-sided paresthesia. The paresthesia initiated in the left hand, along with weakness and reduced fine motor control, and then spread to the entire left side of the body. He had recent weight loss, imbalance, difficulty in swallowing, and hoarseness in his voice. He also had a diminished gag reflex, and significant atrophy of the right side of the tongue with an accompanying deviation of the uvula and fasciculations of the tongue. MRI showed an infiltrative expansile mass within the medulla with peripheral enhancement and central necrosis. In T2/FLAIR sequences, a hyperintense signal extended superiorly into the left inferior aspect of the pons and left inferior cerebellar peduncle and inferiorly into the upper cervical cord.The decision was made to proceed with surgical resection. The patient underwent a midline suboccipital craniotomy with C1 laminectomy for surgical resection of this infiltrative expansile intrinsic mass in the medulla oblongata, with concurrent monitoring of motor and somatosensory evoked potentials and monitoring of lower cranial nerves IX, X, XI, and XII. A gross-total resection of the enhancing portion of the tumor was performed, along with a subtotal resection of the nonenhancing portion. The surgery and postoperative course were uneventful. Histopathology revealed a grade IV astrocytoma. The patient received radiation therapy.In this surgical video, we demonstrate important steps for the microsurgical resection of this challenging glioblastoma multiforme of the medulla oblongata.The video can be found here: https://youtu.be/QHbOVxdxbeU.

Endings of the vagus nerve fibers in the mammalian heart

1927 ◽  
Vol 23 (6-7) ◽  
pp. 622-623
Author(s):  
B. I. Lavrent'ev
Keyword(s):  
Methylene Blue ◽  
Vagus Nerve ◽  
Nerve Fibers ◽  
Nerve Cells ◽  
Vagus Nerves ◽  
Mammalian Heart ◽  
Cardiac Ganglia ◽  
Important Study ◽  
Spiral Fibers

In 1893, Prof. V.V. Nikolaev, having cut vagus nerves of a frog, saw under a microscope degeneration of so-called spiral fibers and pericellular apparatuses on nerve cells of intracardiac nodes. Later these observations were thoroughly verified by Prof. D.V. Polumordvinov and fully confirmed by him. I had a chance to look through amazing by technique preparations of the late Prof. Polumordvinov, obtained by methylene blue method, on which decay of pericellular apparatuses in cardiac ganglia of a frog was absolutely clearly visible. D. V-ch, who died untimely in 1919, unfortunately, did not have time to publish in detail his important study; the manuscript and drawings of his work also remained undiscovered.

scholarly journals Daily temperature dynamics of human skin representative areas

2016 ◽  
Vol 21 (2) ◽  
pp. 86-91
Author(s):  
S. Goncharevskyi ◽  
V. Martynyuk
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Vagus Nerve ◽  
Temperature Variation ◽  
Human Skin ◽  
Medulla Oblongata ◽  
Brain Structures ◽  
Infrared Thermometer ◽  
Autonomic Nervous ◽  
Temperature Dynamics

The main aim of our research was to study the temperature variation of representative are a soft the cranial part of the autonomic nervous system of the human skin during the day. The temperature of representative are a soft the thoracic autonomic nervous system we measured by infrared thermometer (Medisana FTO D-53340, with anaccuracy of 0.1 degree Celsius). During the study identified minimums and maximums temperatures for representative are as during the day: the hypothalamus – 13 (maximum), 3 (minimum) an hour, midbrain – 15 (maximum), 5 (minimum) an hour, pons- not found, the medulla oblongata – 9, 15 (maximum), 3.21 (minimum) an hour, the vagus nerve (right side) – 15 (maximum), 5 (at least) an hour, the vagus nerve (left side) – 15 (maximum), 21 (minimum) an hour. The presence of minimums and maximums temperature in representative areas indicates different activity related to their brain structures.

scholarly journals THE INFLUENCE OF THE VAGUS NERVES UPON CONDUCTION BETWEEN AURICLES AND VENTRICLES IN THE DOG DURING AURICULAR FIBRILLATION

1916 ◽  
Vol 24 (5) ◽  
pp. 605-619 ◽  
Author(s):  
G. Canby Robinson
Keyword(s):  
Vagus Nerve ◽  
Vagus Nerves ◽  
The Right ◽  
Left Vagus ◽  
Stimulation Of

The experiments that have been reported indicate that stimulation of either the right vagus or the left vagus nerve is equally effectual in blocking impulses from the auricles to the ventricles when auricular fibrillation is present. Stimulation of the left vagus nerve is as effectual in blocking impulses from the normally beating auricles as from the auricles when in a state of fibrillation, and the type of auricular activity has apparently no influence on the effect which stimulation of the left vagus has on auriculoventricular conduction.

The effects of transecting the IXth and Xth cranial nerves on hydromineral balance in the eel Anguilla anguilla

1976 ◽  
Vol 64 (2) ◽  
pp. 461-475
Author(s):  
N. Mayer-Gostan ◽  
T. Hirano
Keyword(s):  
Fresh Water ◽  
Sea Water ◽  
Cranial Nerves ◽  
Anguilla Anguilla ◽  
Vagus Nerves ◽  
Rapid Reduction ◽  
Ion Concentrations ◽  
Excess Loss ◽  
Na Efflux ◽  
Hydromineral Balance

The IXth and the Xth cranial nerves in Anguilla anguilla were transected, and the effects upon ion and water balance were studied in fresh water and sea water, and during transfer from fresh water and vice versa. In fresh water there is a slow demineralization due to an excess loss of Na and Cl ions. During freshwater to seawater transfer the eel survives only for 4–5 days. The fish do not drink and Na efflux does not increase enough to extrude excess ions. In sea water the glossopharyngeal and vagus nerves are necessary for the maintenance of the hydromineral balance. Denervation is followed by an increase in plasma ion concentrations. Na fluxes are not modified and increased water loss is not compensated by drinking. The rapid reduction of Na efflux during transfer from sea water to fresh water is not modified by denervation.

Two rhombomeres are altered in Hoxa-1 mutant mice

Development ◽  
1993 ◽  
Vol 119 (2) ◽  
pp. 319-338 ◽  
Author(s):  
M. Mark ◽  
T. Lufkin ◽  
J.L. Vonesch ◽  
E. Ruberte ◽  
J.C. Olivo ◽  
...  
Keyword(s):  
Neural Crest ◽  
Motor Neurons ◽  
Cranial Nerves ◽  
Three Dimensional ◽  
Neural Crest Cell ◽  
Mutant Mice ◽  
Morphological Data ◽  
Vagus Nerves ◽  
Membranous Labyrinth ◽  
Free Region

This study provides a detailed description of the anatomical defects in the Hoxa-1−/− mutant mice previously generated in our laboratory (T. Lufkin, A. Dierich, M. LeMeur, M. Mark and P. Chambon, 1991; Cell 66, 1105–1119). Three-dimensional reconstructions of the Hoxa-1−/− rhombencephalon reveals that it bears only five rhombomeric structures (ie. morphological segments) instead of the normal seven. The first three of these rhombomeres appear normal as judged from the distribution pattern of CRABPI transcripts in the neurectoderm and from the histological analysis of the cranial nerve components derived from these structures. In contrast, the neural-crest-cell-free region normally located opposite rhombomere 5 is lacking in Hoxa-1−/− embryos, and motor neurons of the facial and abducens nerves, which normally differentiate within rhombomeres 4, 5 and 6, are missing in Hoxa-1−/− fetuses. These morphological data, combined with the determination of the molecular positional identities of the rhombomeres 4 and 5 (P. Dolle, T. Lufkin, R. Krumlauf, M. Mark, D. Duboule and P. Chambon, 1993; Proc. Natl. Acad. Sci. USA, in press), suggest that rhombomere 4 is markedly reduced, whereas rhombomere 5 is almost absent. Thus, the remnants of rhombomeres 4 and 5 appear to be fused caudally with rhombomere 6 to form a single fourth rhombomeric structure. Moreover, the migration of neural crest cells contributing to the glossopharyngeal and vagus nerves occurs in a more rostral position, resulting in abnormalities of these cranial nerves, which were visualized by whole-mount anti-neurofilament immunostaining. The mutual relationship along the rostrocaudal axis between the otic pit and the neuroepithelial site of int-2 protein secretion (a putative otogenic cue) is not significantly changed in Hoxa-1−/− embryos. However, the abnormal relationship between the rhombencephalon and the epithelial inner ear may account for the aplasia and faulty differentiation of the membranous labyrinth, the disruption of the cartilaginous otic capsule and the disorganisation of some middle ear structures. This phenotype is compared with that of the Hoxa-1−/− mutants generated by O. Chisaka, T. S. Musci and M. R. Capecchi, 1992 (Nature 335, 516–520) and with that of the mice homozygous for the kreisler mutation.

Medulla Oblongata and Cranial Nerves.

2006 ◽  
pp. 175-185
Author(s):  
G. L. Freeman
Keyword(s):  
Medulla Oblongata ◽  
Cranial Nerves

scholarly journals Intracranial nonvestibular neurinomas: Young neurosurgeons’ experience

2014 ◽  
Vol 05 (03) ◽  
pp. 231-243
Author(s):  
Forhad Hossain Chowdhury ◽  
Mohammod R. Haque ◽  
Khandkar A. Kawsar ◽  
Mainul H. Sarker ◽  
Mahmudul Hasan ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Cranial Nerve ◽  
Cranial Nerves ◽  
Craniovertebral Junction ◽  
Jugular Foramen ◽  
Clinical Profile ◽  
Clinical Feature ◽  
Subtotal Resection ◽  
Total Resection

ABSTRACT Background and Objectives: Neurinoma arising from other than nonvestibular cranial nerves is less prevalent. Here we present our experiences regarding the clinical profile, investigations, microneurosurgical management, and the outcome of nonvestibular cranial nerve neurinomas. Materials and Methods: From January 2005 to December 2011, the recorded documents of operated nonvestibular intracranial neurinomas were retrospectively studied for clinical profile, investigations, microneurosurgical management, complications, follow-up, and outcomes. Results: The average follow-up was 24.5 months. Total number of cases was 30, with age ranging from 9 to 60 years. Sixteen cases were males and 14 were females. Nonvestibular cranial nerve schwannomas most commonly originated from trigeminal nerve followed by glossopharyngeal+/vagus nerve. There were three abducent nerve schwannomas that are very rare. There was no trochlear nerve schwannoma. Two glossopharyngeal+/vagus nerve schwannomas extended into the neck through jugular foramen and one extended into the upper cervical spinal canal. Involved nerve dysfunction was a common clinical feature except in trigeminal neurinomas where facial pain was a common feature. Aiming for no new neurodeficit, total resection of the tumor was done in 24 cases, and near-total resection or gross total resection or subtotal resection was done in 6 cases. Preoperative symptoms improved or disappeared in 25 cases. New persistent deficit occurred in 3 cases. Two patients died postoperatively. There was no recurrence of tumor till the last follow-up. Conclusion: Nonvestibular schwannomas are far less common, but curable benign lesions. Surgical approach to the skull base and craniovertebral junction is a often complex and lengthy procedure associated with chances of significant morbidity. But early diagnosis, proper investigations, and evaluation, along with appropriate decision making and surgical planning with microsurgical techniques are the essential factors that can result in optimum outcome.

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