The structure and risk factors of the postoperative cerebral dysfunction in oncosurgery

Aim of the research was to study the features of the structure of postoperative cerebral dysfunction, establishing the risk factors for the development of postoperative cerebral dysfunction and for the each of the clinical types during operations for malignant neoplasms of the chest and abdomen. The study was conducted in 2 stages: a retrospective study based on medical records and a prospective study. In a retrospective study by the method of directed selection from 93,129 clinical cases of patients, 47 cases of patients with acute stroke after surgery were selected. In prospective study, 102 patients (69 men, 33 women) aged 38 to 85 years were examined, the median age was 67 years. They were divided into two study groups: thoracic, abdominal. In a retrospective study, the incidence of perioperative stroke was 0.05%. In a prospective study of surgical operations for malignant neoplasms of the chest and abdomen, the incidence of postoperative cerebral dysfunction was 34%, perioperative stroke 2%, symptomatic delirium of the early postoperative period 11%, deferred cognitive impairment 31%. Statistical processing of the prospective study data revealed 10 risk factors for postoperative cerebral dysfunction, 12 risk factors for perioperative stroke, 7 risk factors for symptomatic delirium of the early postoperative period, and 6 risk factors for deferred cognitive impairment. For each of the clinical types of postoperative cerebral dysfunction the Charlson comorbidity index has a significant predictive value, and therefore it seems appropriate to include this parameter in the preoperative examination algorithm (3 tables, bibliography: 8 refs)

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Risk factors for single and recurrent falls: A prospective study of falls in community dwelling seniors without cognitive impairment

Preventive Medicine ◽

10.1016/j.ypmed.2013.07.012 ◽

2013 ◽

Vol 57 (5) ◽

pp. 511-517 ◽

Cited By ~ 31

Author(s):

Tai-Yin Wu ◽

Wei-Chu Chie ◽

Rong-Sen Yang ◽

Kuan-Liang Kuo ◽

Wai-Kuen Wong ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Prospective Study ◽

Community Dwelling ◽

Recurrent Falls ◽

A Prospective Study

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Local Anesthesia and Conscious Sedation Does Not Affect Patient's Mood and Anxiety Levels during Percutaneous Endoscopic Lumbar Diskectomy: A Prospective Study

Journal of Neurological Surgery Part A Central European Neurosurgery ◽

10.1055/s-0041-1739203 ◽

2021 ◽

Author(s):

H. Yener Erken ◽

Oguz Karaeminogullari ◽

Onur Yilmaz ◽

Kerem Mirel ◽

R. Ozgur Ozer

Keyword(s):

Prospective Study ◽

Operating Room ◽

Local Anesthesia ◽

Postoperative Period ◽

Conscious Sedation ◽

Early Postoperative Period ◽

Preoperative Period ◽

Significant Difference ◽

Anxiety Levels ◽

A Prospective Study

Abstract Background and Study Aims Undergoing a surgical procedure can be very stressful for patients and can lead to high anxiety levels during both the preoperative and the postoperative period. Levels of anxiety and fear may depend on multiple factors including the type of anesthesia to be used. The objective of this study is to evaluate whether patient's awareness of the surgical environment in the operating room under local anesthesia and conscious sedation (LACS) affects their mood and anxiety levels. Methods We performed a prospective study for a series of consecutive patients who underwent transforaminal percutaneous endoscopic lumbar diskectomy (PELD) for the treatment of lumbar disk herniation. The patients completed Profile of Mood States (POMS) and State-Trait Anxiety Inventory (STAI) forms in the preoperative period and in the early postoperative period. We divided the patients into two groups according to the type of anesthesia applied during surgery: LACS and general anesthesia (GA) groups. We compared the preoperative and postoperative POMS and STAI scores between groups and the change of these scores between the preoperative and postoperative periods in each group. Results In this study, we included 30 patients who underwent PELD between May and December 2019 and met the inclusion criteria. The GA group consisted of 16 patients and the LACS group consisted of 14 patients. In each group, POMS and STAI scores decreased in the early postoperative period compared with the preoperative period. We found no significant difference in percentage of POMS and STAI TX-1 score changes between the LACS and GA groups. Conclusion The results of our study show that patients' awareness of the surgical environment in the operating room under LACS does not significantly affect their mood and anxiety levels and patients do not seem to endure increased emotional stress during the PELD operation, as compared with PELD operation under GA.

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PREVALENCE AND RISK FACTORS OF ESSENTIAL HYPERTENSION AND NEW ONSET OF DIABETES IN ESSENTIAL HYPERTENSION IN RURAL POPULATION OF HARYANA

International Journal of Pharmacy and Pharmaceutical Sciences ◽

10.22159/ijpps.2018v10i2.23891 ◽

2018 ◽

Vol 10 (2) ◽

pp. 142

Author(s):

Vikas Jhawat ◽

Sumeet Gupta ◽

Bimal K. Agarwal ◽

Partha Roy ◽

Vipin Saini

Keyword(s):

Risk Factors ◽

Essential Hypertension ◽

Retrospective Study ◽

Prospective Study ◽

Anthropometric Parameters ◽

Prescription Pattern ◽

Onset Of Diabetes ◽

Associated Risk Factors ◽

A Prospective Study ◽

New Onset

Objective: We conducted a well-designed prevalence study in a rural population of Haryana in Mullana rural area to find out the latest prevalence of essential hypertension, the prescription pattern of antihypertensive drugs and the associated risk of new onset of diabetes.Methods: A retrospective study was carried out on the patient data (2672 patients) from the years 2009 to 2013 at OPD of M. M. University hospital, Mullana to find the previous year’s prevalence of different diseases, including essential hypertension, new onset of diabetes and associated risk factors, prescription pattern of antihypertensive drug therapy. Based on the above results, a prospective study was conducted from January 2015 to December 2016 and total 510 patients (270 essential hypertension and 240 essential hypertension with new onset of diabetes) and 270 normal individuals were recruited in the study.Results: The retrospective study, a total of 2672 patients' data was evaluated which showed 41.21% prevalence of essential hypertension, 11.83% new onset of diabetes in Essential hypertension patients and 15.87% diabetic patients. Antihypertensive monotherapy was prescribed to 59.85% patients and combination therapy to 40.15% patients while that of a prospective study showed 40.37% patients of monotherapy and 59.63% patients of combination therapy. The prospective study also showed that different anthropometric parameters were significantly associated with risk of hypertension and new onset of diabetes except for age and height.Conclusion: An increase in the prevalence of essential hypertension and associated risk factors was observed when compared with previous studies and retrospective study. It is clearly seen by the change in drug therapy pattern and different anthropometric parameters. Implementation of a large scale awareness program is needed to combat these metabolic diseases.

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