CLINICAL FEATURES, DIAGNOSIS, THE RESULTS OF THERAPEUTIC AND SURGICAL TREATMENT OF ACANTHAMOEBIC KERATITIS

ABSTRACTAsymmetric ventriculomegly due to idiopathic occlusion of the foramen of Monro is rare. Such patients present with clinical features of raised intracranial pressure (ICP). Presentation as chronic headache has not been previously described. In the absence of raised ICP, pursuing surgical treatment raises a clinical dilemma as the headache may be a primary headache with no improvement after surgery. A 21-year-old woman presented with chronic headache. She was found to have asymmetric ventriculomegaly due to the occlusion of the foramen of Monro. She underwent endoscopic septostomy and widening of the foramen of Monro. Her headache subsided after surgery. At 15 months of follow-up, she was free from headache without medications. Unilateral occlusion of the foramen of Monro can present with asymmetric ventriculomegaly resulting in chronic headache. Though the symptoms of raised ICP may not be present, still endoscopic relief of ventriculomegaly leads to cure of headache.

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Pulmonary carcinosarcoma: analysis from the Surveillance, Epidemiology and End Results database

Interactive CardioVascular and Thoracic Surgery ◽

10.1093/icvts/ivz215 ◽

2019 ◽

Vol 30 (1) ◽

pp. 4-10 ◽

Cited By ~ 2

Author(s):

Liangdong Sun ◽

Jie Dai ◽

Xujun Wang ◽

Gening Jiang ◽

Diego Gonzalez-Rivas ◽

...

Keyword(s):

Surgical Treatment ◽

Cell Carcinoma ◽

Clinical Features ◽

Cox Regression ◽

Multivariable Analysis ◽

Area Under The Curve ◽

Concordance Index ◽

Elderly Age ◽

Pulmonary Carcinosarcoma ◽

End Results

Abstract OBJECTIVES Pulmonary carcinosarcoma (PCS) is a rare neoplasm. This study explored the clinicopathological characteristics and survival outcomes of PCS. METHODS The Surveillance, Epidemiology and End Results (SEER) database (1988–2014) was queried for PCS. Overall survival (OS) was evaluated by multivariable Cox regression and nomograms were constructed to predict 3-year OS for PCS. Prognostic performance was evaluated using concordance index and area under the curve analysis. In M0 surgically treated patients, interaction assessments were performed using likelihood ratio tests. Subgroup analysis was performed according to patient age. The clinical features of PCSs were further compared to other non-small-cell lung cancers (NSCLCs). RESULTS Multivariable analysis identified age [hazard ratio (HR) 1.03, 95% confidence interval (CI) 1.01–1.04], surgery (HR 0.53, 95% CI 0.36–0.77) and chemotherapy (HR 0.51, 95% CI 0.36–0.73) as significantly associated with OS. The nomogram had a concordance index of 0.747 and an area under the curve of 0.803. The association between age and OS was stronger in those receiving pneumonectomy (P = 0.04 for interactions) compared to those that did not (HR 5.14, 95% CI 1.64–16.07), and was associated with a poorer outcome compared to lobectomy amongst the elderly (age ≥ 70 years). Patients with PCS were more likely to receive surgical treatment and had lower lymphatic metastasis compared to adenocarcinoma, squamous cell carcinoma and large cell carcinoma (all P < 0.05). CONCLUSIONS PCS had unique clinical features compared to common types of NSCLCs in terms of lymphatic invasion and surgical treatment. Pneumonectomy was associated with poorer survival in elderly patients.

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Intramedullary inclusion cysts of the cervicothoracic junction

Journal of Neurosurgery Spine ◽

10.3171/spi-07/08/236 ◽

2007 ◽

Vol 7 (2) ◽

pp. 236-242 ◽

Cited By ~ 22

Author(s):

Alfred T. Ogden ◽

Alexander G. Khandji ◽

Paul C. McCormick ◽

Michael G. Kaiser

Keyword(s):

Spinal Cord ◽

Case Report ◽

Surgical Treatment ◽

Dermoid Cyst ◽

Clinical Features ◽

Epidermoid Cyst ◽

Relevant Literature ◽

Literature Discussion ◽

Cervicothoracic Junction

✓Intramedullary inclusion cysts are extremely rare within the rostral spinal cord. In this case report the authors outline the clinical features and surgical treatment of one dermoid cyst and one epidermoid cyst of the cervicothoracic junction. The authors also include a relevant literature discussion regarding the treatment and the embryological origin of these lesions.

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