scholarly journals Being Disoriented: Uncertain Encounters with Disability

2016 ◽  
Vol 36 (2) ◽  
Author(s):  
Ryan C. Parrey
Keyword(s):  
Disability Studies ◽  
Meeting Point ◽  
Open Question ◽  
The Relationship

<p>Disorienting encounter with disability are those in which the meaning of disability is an open question, and in which our relation to it is questionable. This essay explores the relationship between disability and disorientation on conceptual but also concrete levels. First, I examine the connection between disability and disorientation within disability studies. Second, I provide a preliminary sketch of disorientation through what I call <em>ontic disruption</em> and <em>ontological disorientation</em>. Third, I take up Leder's (1990) articulation of bodily disappearance and embodied dysappearance to address ableist violence. Finally, I develop the notion of <em>dysorientation — </em>a prolonged, persistent or recurrent sense of disorientation — as a useful concept for understanding experiences of ableism but also as a significant meeting point between impairment and disability. </p><p> </p>

scholarly journals From Culture 1.0 to Culture 3.0: Three Socio-Technical Regimes of Social and Economic Value Creation through Culture, and Their Impact on European Cohesion Policies

2018 ◽  
Vol 10 (11) ◽  
pp. 3923 ◽  
Author(s):  
Pier Sacco ◽  
Guido Ferilli ◽  
Giorgio Tavano Blessi
Keyword(s):  
Cultural Production ◽  
Value Creation ◽  
Cultural Policy ◽  
Policy Design ◽  
Economic Value ◽  
Cultural Participation ◽  
Social Value Creation ◽  
Open Question ◽  
The Relationship

We develop a new conceptual framework to analyze the evolution of the relationship between cultural production and different forms of economic and social value creation in terms of three alternative socio-technical regimes that have emerged over time. We show how, with the emergence of the Culture 3.0 regime characterized by novel forms of active cultural participation, where the distinction between producers and users of cultural and creative contents is increasingly blurred, new channels of social and economic value creation through cultural participation acquire increasing importance. We characterize them through an eight-tier classification, and argue on this basis why cultural policy is going to acquire a central role in the policy design approaches of the future. Whether Europe will play the role of a strategic leader in this scenario in the context of future cohesion policies is an open question.

scholarly journals Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation

2019 ◽  
Author(s):  
Fabiana Cerqueira Campos ◽  
Cynthia Dennis ◽  
Hervé Alégot ◽  
Cornelia Fritsch ◽  
Adam Isabella ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Ovarian Follicle ◽  
Follicle Cell ◽  
Autonomous Control ◽  
Stress Fibers ◽  
Follicle Growth ◽  
Growth Promoting ◽  
Fibers Orientation ◽  
Open Question ◽  
The Relationship

SummaryHow extracellular matrix participates to tissue morphogenesis is still an open question. In the Drosophila ovarian follicle, it has been proposed that after Fat2-dependent planar polarization of the follicle cell basal domain, oriented basement membrane (BM) fibrils and F-actin stress fibers constrain follicle growth, promoting its axial elongation. However, the relationship between BM fibrils and stress fibers and their respective impact on elongation are unclear. We found that Dystroglycan (Dg) and Dystrophin (Dys) are involved in BM fibril deposition. Moreover, they orient stress fibers, by acting locally and in parallel to Fat2. Nonetheless, Dg-Dys complex-mediated cell autonomous control of F-actin fibers orientation relies on the previous BM fibril deposition, indicating two distinct but interdependent functions. Thus, the Dg-Dys complex works as a critical organizer of the epithelial basal domain, regulating both F-actin and BM. Furthermore, BM fibrils act as a persistent cue for the orientation of stress fibers that are the main effector of elongation.

The Negative Effects of Using Smart Devices on the Physical and Psychological Health of Palestinian Children aged (13-16) years from their Perspective

2020 ◽  
Vol 8 (3) ◽  
pp. 01-19
Author(s):  
Nuha Iter
Keyword(s):  
Psychological Health ◽  
Smart Devices ◽  
Smart Device ◽  
Negative Effects ◽  
Physical And Psychological Health ◽  
Palestinian Children ◽  
Open Question ◽  
High Degree ◽  
The Relationship ◽  
Descriptive Method

The study aimed to explore the negative effects of using smart devices on the physical and psychological health of children aged (13-16) years from their perspective. The study was applied to a random sample of children aged (13-16), consisting of (102) male and female students. The descriptive method was used to answer the study questions, and a questionnaire was developed to collect data, which contains (3) sections, first section asked about the most used and preferred devices by children aged (13-16) years, and the number of hours the child used the smart device, the second one asked about the negative effects of using the smart devices on the physical and psychological health of children aged (13-16) years from their perspective, and the third section is an open question to know other negative effects of using the smart devices on the physical and psychological health of children aged (13-16) years. The study achieved a set of results, such as the smartphones are the most used and preferred devices by children aged (13-16) years, where (57%) of the study sample preferred to use, and there is  (86.3%) of children aged (13-16) use these devices at average from 4 up to 6 hours daily.  The responders highly agreed upon the negative effects of the use of smart devices on the physical health with average (4.2); which is a high degree, also the responders highly agreed upon the negative effects of  the use of smart devices on the physiological health with average  is  (3.73) which is also high,  added there are other effects caused by the use of smart devices for long hours on  children aged (13-16); the low rate of family discussions, and causes the low writing skills for child.   Depending on the results of the study, the researcher recommends that:  researchers should conduct a correlative study to know the relationship between the effects and the number of hours of daily use of devices; families should rationalize the use of smart devices.

Abnormally high variability in the uncrossed retinofugal pathway of mice with albino mosaicism

Development ◽  
1987 ◽  
Vol 101 (4) ◽  
pp. 857-867 ◽  
Author(s):  
R.W. Guillery ◽  
G. Jeffery ◽  
B.M. Cattanach
Keyword(s):  
Retinal Ganglion Cells ◽  
Ganglion Cells ◽  
Gene Dosage ◽  
Optic Tract ◽  
High Variability ◽  
Retinal Ganglion ◽  
Rare Occurrence ◽  
Autosome Translocation ◽  
Open Question ◽  
The Relationship

Female mice showing albino mosaicism due to an X-autosome translocation [Is(In7;X)Ct] have been studied in order to investigate the relationship between the distribution of melanin and the formation, early in development, of the abnormally small uncrossed retinofugal pathway characteristically found in all albino mammals. Earlier evidence indicates that cells normally bearing melanin play a role in producing the abnormality. In the mosaic mice, the albino gene is expressed in only about half of the cells due to random X-inactivation and the patches of normal and albino cells are extremely small relative to total retinal size (less than 1/50). We argued that if all the cells that would normally bear melanin play a role in producing the albino abnormality then the mosaic mice would have a pathway abnormality, about half the size of that in the albino mice. If, however, only a small patch of these cells plays a role, as has been proposed in earlier studies, then one would expect the size of the uncrossed pathway to be highly variable in the mosaic mice. The size of the uncrossed pathway was assessed by placing horseradish peroxidase in the region of the optic tract and lateral geniculate nucleus unilaterally and then counting the number of retrogradely labelled retinal ganglion cells on the same side. The mosaic mice showed a highly variable uncrossed pathway. In some of the mosaic mice, it was the same size as in the albinos and, in others, it was the same size as in normally pigmented mice. Surprisingly, in a small number of mosaic mice, the uncrossed pathway was larger than normal. Whether this relatively rare occurrence of a supernormal uncrossed pathway is due to the higher gene dosage or to the translocation itself remains an open question.

How to Argue for Law’s Full-Blooded Normativity

2019 ◽  
pp. 165-186
Author(s):  
George Letsas
Keyword(s):  
Moral Philosophy ◽  
Moral Concern ◽  
Legal Practice ◽  
Top Down ◽  
Specific Practice ◽  
Open Question ◽  
The Relationship

This chapter aims to make space for the view that law possesses full-blooded normativity in a top-down way. Here is the dialectic of the inquiry: What would have to be true of morality for the claim that some specific practice is full-bloodedly normative to be plausible? The chapter assumes that the practice of morality as a whole has full-blooded normativity in the sense that its requirements give one genuine reasons to act, irrespective of one’s subjective wants, desires, and beliefs. The focus is on what it means to say of a specific practice that it partakes of morality’s normativity. The reason is simple: it should be an open question whether this or that practice has full-blooded normativity. For if it is not possible for any particular practice to have full-blooded normativity, then the question of whether law has full-blooded normativity would make no sense from the get-go. The account put forward builds on the idea of obligations of role. A practice, has full-blooded normativity when it instantiates a distinct set of obligations, one that pertains to people in a particular capacity, such as friends, parents, doctors, or teachers. The proposition that there are distinct moral practices, which are not reducible to a single moral concern, is of course disputed territory in moral philosophy. But if this proposition is accepted, one can ask, by analogy, whether legal practice instantiates an obligation of role and, as a result, bears the attributes of full-blooded normativity. This way of proceeding perceives the relationship between law and metaethics differently: it shows that law’s claim to full-blooded normativity ultimately depends on contestable assumptions about the nature of morality as a whole.

scholarly journals Exploring the Influence of the Level of Technology and Expected Functions in Product Semantic

2019 ◽  
Vol 1 (1) ◽  
pp. 3881-3890
Author(s):  
SoJeong Kim ◽  
JungKyoon Yoon ◽  
Chajoong Kim
Keyword(s):  
User Satisfaction ◽  
Development Process ◽  
Product Development Process ◽  
Smart Technology ◽  
Hedonic Value ◽  
Smart Watch ◽  
On Line ◽  
Research Questions ◽  
Open Question ◽  
The Relationship

AbstractThis study attempted to explore how pragmatic and hedonic values are influenced by the level of technology and what particular functions have to be considered in the context of smart technology- driven design in terms of Pragmatic Value (PV) and Hedonic Value (HV). An on-line questionnaire survey was developed to answer the research questions. A total of 104 respondents participated in the survey. As target product for the study, analog watch and smart watch were selected as representative of low and high technology respectively. Semantic Differentials on PV and HV were used and expected functions were investigated via an open question. The results indicate that there are some differences between analog and smart watches in terms of PV and HV. Regarding expected functions, significant differences were identified in the study. The findings from the study could provide a better understanding of the relationship between PV and HV in terms of level of technology. If it is considered in product development process, it may contribute to an increase of user satisfaction with smart- technology based product and service.

The Is-Ought Problem, the Open Question Argument, and the new science of morality

Human Affairs ◽  
2011 ◽  
Vol 21 (3) ◽  
Author(s):  
Radim Bělohrad
Keyword(s):  
New Science ◽  
Open Question Argument ◽  
Open Question ◽  
The Relationship ◽  
Is Ought Problem ◽  
Recent Attack

AbstractThe article deals with a recent attack by Sam Harris on two famous arguments that purport to establish a gap between factual and evaluative statements—Hume’s Is-Ought Problem and Moore’s Open Question Argument. I present the arguments, analyze the relationship between them and critically assess Harris’ attempt to refute them. I conclude that Harris’ attempt fails.

scholarly journals Toward training surgeons with motion-based feedback: Initial validation of smoothness as a measure of motor learning

2017 ◽  
Vol 61 (1) ◽  
pp. 1531-1535 ◽  
Author(s):  
Shivam Pandey ◽  
Michael D. Byrne ◽  
William H. Jantscher ◽  
Marcia K. O’Malley ◽  
Priyanshu Agarwal
Keyword(s):  
Skill Acquisition ◽  
Motor Task ◽  
Subsequent Work ◽  
Motor Skill Acquisition ◽  
Movement Smoothness ◽  
Overall Performance ◽  
And Performance ◽  
Multiple Domains ◽  
Open Question ◽  
The Relationship

Surgery is a challenging domain for motor skill acquisition. A critical contributing factor in this difficulty is that feedback is often delayed from performance and qualitative in nature. Collection of highdensity motion information may offer a solution. Metrics derived from this motion capture, in particular indices of movement smoothness, have been shown to correlate with task outcomes in multiple domains, including endovascular surgery. The open question is whether providing feedback based on these metrics can be used to accelerate learning. In pursuit of that goal, we examined the relationship between a motion metric that is computationally simple to compute—spectral arc length—and performance on a simple but challenging motor task, mirror tracing. We were able to replicate previous results showing that movement smoothness measures are linked to overall performance, and now have performance thresholds to use in subsequent work on using these metrics for training.

scholarly journals ON THE BEGINNING OF THE EARLY IRON AGE IN THE TERRITORY OF MIDDLE DON BASIN

2019 ◽  
Vol 31 (2) ◽  
pp. 92-101
Author(s):  
A. P. Medvedev ◽  
R. S. Berestnev
Keyword(s):  
Iron Age ◽  
Early Iron Age ◽  
Forest Steppe ◽  
Funerary Monuments ◽  
Metal Plates ◽  
Regional Specificity ◽  
Open Question ◽  
Cultural Genesis ◽  
The Relationship

The article is devoted to the characterization of pre-Scythian time monuments in the forest-steppe course of the Don. The authors come to the conclusion about the regional specificity of the process of cultural genesis in this territory at the beginning of the early Iron Age. The authors analyze the new treasure of Novocherkassk type. It was opened in 2016 in the Podgorensky district of the Voronezh region. This treasure includes psalms, hatchet, metal plates, bracelet-like rings, spearheads. In inventory, it is close to the pre-Scythian burials in the forest-steppe Ukraine (Butenki, Kvitki). Obviously, the population that left the treasure penetrated into the territory of the Middle Don region from the steppes between the Dnieper and Ciscaucasia — the place where the Cimmerian culture was formed in the 9th century. Objects close to the Proto-Meotian, Novocherkassk complexes, their diversity show this process. It remains an open question about the relationship in the studied region of the funerary monuments of Novocherkassk type and Middle-Don mounds of the Scythian time.

scholarly journals Locality and Non locality

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
Ilija Barukčić
Keyword(s):  
Probability Theory ◽  
Quantum Mechanics ◽  
Pythagorean Theorem ◽  
Quantum Probabilities ◽  
Open Question ◽  
Relativistic Concept ◽  
The Relationship ◽  
Non Locality

Aim: Whether, under all the circumstances considered, a relativistic concept of locality and non-locality may fully reproduce the quantum probabilities for outcomes of experiments, is re-investigated.Methods: The usual methods and rules of statistics, probability theory and quantum mechanics were used. Results: The interior logic of the variance has been re-investigated. A relationship between the Pythagorean theorem and the variance has been established. A n-dimensional Pythagorean theorem has been derived. The problem of locality and non-locality and the relationship to the variance has been analysed.Conclusion: It may no longer stay an open question how to deal with the notions of locality and non-locality.

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