scholarly journals Treatment of Patients with Scoliosis Using a Unique Anterior Scoliosis Correction Technique

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Christopher Antonacci ◽  
M. Antonacci ◽  
William Bassett ◽  
Janet Cerrone ◽  
Allison Haas ◽  
...  
Keyword(s):  
Facet Joint ◽  
Skeletal Maturity ◽  
Curve Progression ◽  
Spinal Mobility ◽  
Surgical Approaches ◽  
Growth Modulation ◽  
Trunk Deformity ◽  
Correction Technique ◽  
Scoliosis Correction ◽  
Facet Joint Degeneration

Treatment for adolescent idiopathic scoliosis (AIS) is dependent upon multiple factors, including curve type and magnitude, curve progression, skeletal maturity, and clinical trunk deformity. While fusion is effective at achieving curve correction, it is associated with disadvantages including prominent implants beneath the skin, back muscle scarring and atrophy, decreased spine range of motion, and decreased functional spinal mobility. Additional concerns include the potential for longer term development of premature adjacent level disc and facet joint degeneration above and below the fusion. Due to these issues with spinal fusion, surgeons have explored alternative surgical approaches to correct spinal deformity and halt curve progression using either growth modulation or remodeling of the spine while preserving motion. This paper provides an overview of a non-fusion scoliosis correction technique called Anterior Scoliosis Correction (ASC).

Does Vertebral Body Tethering Cause Disc and Facet Joint Degeneration? A Preliminary MRI Study with Minimum 2-years Follow-up

2021 ◽  
Author(s):  
Altug Yucekul ◽  
Burcu Akpunarli ◽  
Atahan Durbas ◽  
Tais Zulemyan ◽  
Irem Havlucu ◽  
...  
Keyword(s):  
Vertebral Body ◽  
Facet Joint ◽  
Joint Degeneration ◽  
Facet Joint Degeneration ◽  
Mri Study

122. Does vertebral body tethering cause disc and facet joint degeneration? An MRI study with minimum two years of follow-up

2021 ◽  
Vol 21 (9) ◽  
pp. S60
Author(s):  
Altug Yucekul ◽  
Burcu Akpunarli ◽  
Atahan Durbas ◽  
Tais Zulemyan ◽  
Irem Havlucu ◽  
...  
Keyword(s):  
Vertebral Body ◽  
Facet Joint ◽  
Joint Degeneration ◽  
Facet Joint Degeneration ◽  
Mri Study

scholarly journals Facet joint degeneration adversely affects ultrasound imaging of the lumbar spine

2019 ◽  
Vol 21 (2) ◽  
pp. 131
Author(s):  
Karthikeyan Srinivasan ◽  
Hong Kuan Kok ◽  
Mona Mubarak ◽  
William Torregianni ◽  
Robert Whitty
Keyword(s):  
Lumbar Spine ◽  
Ligamentum Flavum ◽  
Facet Joint ◽  
Posterior Longitudinal Ligament ◽  
Joint Degeneration ◽  
Neuraxial Block ◽  
Interspinous Space ◽  
Facet Joint Degeneration ◽  
Experienced Operator ◽  
Magnetic Resonance Imaging Mri

Aim: Ultrasound of neuraxis can be used to identify the best possible inter-spinous space to perform neuraxial block. The aim of this study was to assess the anatomical correlation between neuraxial ultrasound and magnetic resonance imaging (MRI).Material and method: Twenty-one patients who underwent MRI of the lumbar spine had ultrasound of lumbar neuraxis performed by an experienced operator. Each lumbar interspinous space was graded on ultrasound as good [posteriorcomplex (ligamentum flavum and duramater) and anterior complex (posterior longitudinal ligament) visible], intermediate (either anterior complex or posterior complex visible) or poor (both anterior complex and posterior complex not visible) in both the transverse median (TM) and paramedian sagittal oblique (PSO) plane. Pre-determined MRI parameters were measured by a radiologist blinded to sonographic findings at each inter-spinal level.Results: Seventy-eight lumbar interspinous spaces were evaluated. There was a significant association (p<0.004) between the facet joint degeneration on MRI and the poor ultrasound view in the transverse median (TM) group. The odds of obtaining a poor view in TM plane was 7 times higher (95% CI 1.7-28.9, p=0.007) in the presence of facet joint degeneration. None of the other variables had a significant association with a poor neuraxial view in the TM plane. Poor views in the parasagittal oblique (PSO) plane did not correlate with any of the variables measured on MRI.Conclusion: Facet joint degeneration is a major contributing factor to poor neuraxial ultrasound views in the TM plane. 

scholarly journals A Study of Lumbar Disc Herniation and Facet Joint Asymmetry

2019 ◽  
Vol 103 (1-2) ◽  
pp. 87-94
Author(s):  
Qi Lai ◽  
Yuan Liu ◽  
Runsheng Guo ◽  
Xin Lv ◽  
Qiang Wang ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Facet Joint ◽  
Lumbar Disc ◽  
Patients Âgés ◽  
Lower Lumbar Spine ◽  
Significant Difference ◽  
Facet Joint Degeneration ◽  
Disc Herniations ◽  
Lumbar Facet

Purpose: To investigate the association of facet joint asymmetry with lumbar disc herniation at the lower lumbar spine. Methods: A total of 90 patients (ages 18–40 years) with single-level disc herniation (L3–L4, L4–L5, or L5–S1) were included in the study. Facet asymmetry was defined as a difference of 10° in facet joint angles between right and left sides. Normal discs in the same segment of other individuals were used as a control. Patients had facet asymmetry measured for L3 to S1 through 3.0T magnetic resonance imaging, and information was collected, including age, sex, degenerative degree of lumbar facet joints, and the presence or absence of lumbar disc herniation and type. Results: At the L3 to L4 level, 2 cases had facet asymmetry in 8 patients with lumbar disc herniation, compared with 17 cases of facet asymmetry in 82 patients without disc herniation (P = 0.7776, r = 0.030). At the L4 to L5 level, there were 21 cases of facet asymmetry in 45 patients with lumbar disc herniation, compared with 5 cases of asymmetry in 45 patients without disc herniation (P = 0.00019, r = 0.392). At the L5 to S1 level, there were 25 cases of facet asymmetry in 37 patients with lumbar disc herniation, compared with 11 cases of facet asymmetry in 53 patients without disc herniation (P = 0.0000, r = 0.492). There were 23 cases of facet asymmetry in 28 disc herniations of side type compared with 2 cases of facet asymmetry in 9 herniations of center type (P = 0.0008, r = 0.364). There was no significant difference in the relationship between age, facet joint degeneration, and lumbar facet joint asymmetry (P &gt; 0.05). Conclusion: Facet asymmetry is significantly associated with lumbar disc herniation at the L4 to L5 and the L5 to S1 levels, whereas there is an obvious association with the side type of lumbar disc herniation at the L5 to S1 level.

Hsp22 Inhibits Oxidative Stress-Induced Endplate Chondrocyte Apoptosis by Regulating Mitochondrial Pathway

2021 ◽  
Vol 11 (10) ◽  
pp. 1947-1954
Author(s):  
Yi Ye ◽  
Xucan Wang ◽  
Zhenqing Yang ◽  
Qian Xu ◽  
Bo Zhang
Keyword(s):  
Oxidative Stress ◽  
Cell Apoptosis ◽  
Facet Joint ◽  
Mitochondrial Pathway ◽  
Chondrocyte Apoptosis ◽  
Enzyme Linked Immunosorbent Assay ◽  
Ros Generation ◽  
Atp Level ◽  
Facet Joint Degeneration ◽  
Cyt C

Background: Facet joint degeneration (FJD), which is also called facet joint syndrome (FJS), has become one of the most commonly seen etiological factors for lumbago. Cartilage lesion triggered by lumbar facet joint (LFJ) degeneration might be related to mitochondrial impairment, but the its underlying mechanism remains unclear. Materials and methods: The endplate chondrocytes were induced by hydrogen peroxide (H2O2) to mimic the pathological conditions of oxidative stress. Enzyme linked immunosorbent assay (ELISA) were used for the evaluation of reactive oxygen species (ROS). Adenosine-triphosphate (ATP) level was assessed using ATP detection, along with the detection the expression of cytochrome C in mitochondria (mito-cyt c) and in cell cytoplasm (cyto-cyt c) and cleaved caspase 3 by Western blot analysis. TUNEL assay was conducted for the measurement of cell apoptosis in endplate chondrocytes. Reverse transcription-polymerase chain reaction (RT-qPCR) was used to verify the expression of heat shock protein 22 (HSP22) and the transfection efficiency of HSP22 interference plasmid. Results: It was found that H2O2 promoted the mitochondrial dysfunction, ROS generation and cell apoptosis in endplate chondrocytes. Moreover, HSP22 was down-regulated in H2O2-induced endplate chondrocytes, and interference of HSP22 decreased the ROS production, increased the ATP level and promoted the cell apoptosis, resulting in the enhanced impairment of endplate chondrocytes. Additionally, mitochondrial ROS inhibitor (Mito-TEMPO) ameliorated the injury effects of HSP22 silencing in the H2O2-induced endplate chondrocytes. Conclusion: In conclusion, HSP22 inhibits oxidative stress-induced endplate chondrocyte apoptosis by regulating mitochondrial pathway, possibly providing novel guidance direction for the treatment of LFJ degeneration.

scholarly journals When an incidental MRI finding becomes a clinical issue

2019 ◽  
Vol 132 (1-2) ◽  
pp. 27-34
Author(s):  
Ursula Schwarz-Nemec ◽  
Klaus M. Friedrich ◽  
Michael A. Arnoldner ◽  
Felix K. Schwarz ◽  
Michael Weber ◽  
...  
Keyword(s):  
Disc Degeneration ◽  
Facet Joint ◽  
Low Grade ◽  
Obese Patients ◽  
Joint Degeneration ◽  
Clinical Issue ◽  
Hepatic Diseases ◽  
Subcutaneous Edema ◽  
Facet Joint Degeneration ◽  
Magnetic Resonance Imaging Mri

Summary Background On magnetic resonance imaging (MRI), posterior lumbar subcutaneous edema (PLSE) is a frequent incidental, yet unclear finding within the deep subcutaneous perifascial tissue. This study aimed to investigate PLSE in various pathological lumbar conditions. Methods This retrospective study included the MR images of the lumbar spine of 279 patients (age range 18–82 years) without cardiovascular, renal or hepatic diseases, 79 of whom had low-grade disc degeneration, 101 combined endplate and facet joint degeneration, 53 axial spondyloarthritis and 46 infectious spondylodiscitis. There were 232 patients with a body mass index (BMI) <30, and 47 with a BMI ≥30 (obese). For each group, the relationship between PLSE and BMI was analyzed using multiple logistic regression, and between PLSE extension and BMI using ordinal regression. Results A PLSE was found in 11/79 (13.9%) patients with disc degeneration, 37/101 (36.6%) with endplate and facet joint degeneration, 7/53 (13.2%) with spondyloarthritis, and 28/46 (60.9%) with spondylodiscitis. For each group, a statistically significant relationship was demonstrated between PLSE and BMI (P = 0.000–P = 0.031), except for spondylodiscitis (P = 0.054), as well as between PLSE extension and BMI (P = 0.000–P = 0.049). A PLSE was found in 21.1% of nonobese and 72.3% of obese patients (P = 0.000). Conclusion The presence of PLSE seems to be associated with various lumbar conditions, particularly in obese patients. Its perifascial location may suggest a potential fascial origin; however, PLSE should not to be confused with posttraumatic, postsurgical or infectious edema or edema associated with internal diseases.

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