A case report: venous sinus thrombosis in pregnancy

Venous sinus thrombosis (VST) should be considered in the differential diagnosis of all unexplained central nervous system disorders of sudden onset. Etiological factors are subclinical forms of several common thrombophilic states occurring together, rather than the typical inherited and rare causes. Diagnosis is often missed because of the heterogeneity in clinical presentation and radiological investigation is essential for the diagnosis. Prognosis depends on the early detection. By correcting the cause, the complications can be prevented.

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Anticoagulant Therapy for Central Nervous System Venous Sinus Thrombosis - A Retrospective Study

Pediatric Research ◽

10.1203/00006450-199904020-00896 ◽

1999 ◽

Vol 45 (4, Part 2 of 2) ◽

pp. 151A-151A

Author(s):

Nicole F Parkerson ◽

John A Jane ◽

Pedro A de Alarcon

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Retrospective Study ◽

Anticoagulant Therapy ◽

Sinus Thrombosis ◽

Venous Sinus ◽

Venous Sinus Thrombosis

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Cerebral Venous Sinus Thrombosis: An Uncommon Presentation of Headache Mimicking Subarachnoid Hemorrhage

Journal of Medicine ◽

10.3329/jom.v10i2.2826 ◽

1970 ◽

Vol 10 (2) ◽

pp. 115-118

Author(s):

Naima Sultana ◽

Monzurul H Chowdhury ◽

Md Shahriar Mahbub ◽

Md Billal Alam

Keyword(s):

Subarachnoid Hemorrhage ◽

Oral Contraceptives ◽

Sinus Thrombosis ◽

Serum Levels ◽

Cerebral Venous Sinus Thrombosis ◽

Sudden Onset ◽

Interesting Case ◽

Venous Sinus ◽

Venous Sinus Thrombosis ◽

Uncommon Presentation

Cerebral venous sinus thrombosis is a rare disorder accounting for less than 1% of all strokes. It is more common in children and young adults. Here we report a rare and interesting case of cerebral venous l sinus thrombosis mimicking subarachnoid hemorrhage. A 40 years old women, presented with sudden onset of headache, vomiting and unconsciousness associated with convulsions. She had a history of taking oral contraceptives for the last 12 years. Clinical examinations showed ill-looking women with Glasgow Coma Scale of 12 along with neck rigidity and bilateral papilloedema. Although initially we suspected her as a case of subarachnoid hemorrhage, subsequent investigations with MRI and MRV showed to be a case of superior sagittal and transverse sinus thrombosis. Treatment with anticoagulation recovered her from headache and papilloedema. Serum levels of thrombophilic factors were within the normal physiological limits. Thus we concluded that although cerebral venous thrombosis is 100 times less than the cerebral arterial disease, a women presented with sudden onset of headache and vomiting with long term use of oral contraceptives, cerebral thrombosis should be considered as a differential. Key words: Cerebral venous sinus thrombosis , Sagittal sinus thrombosis, Subarachnoid hemorrhage , Magnetic resonance venography. doi: 10.3329/jom.v10i2.2826 J MEDICINE 2009; 10 : 115-118

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Cerebral venous sinus thrombosis in pregnancy: A case report

World Journal of Clinical Cases ◽

10.12998/wjcc.v10.i1.309 ◽

2022 ◽

Vol 10 (1) ◽

pp. 309-315

Author(s):

Biao Zhou ◽

Shan-Shan Huang ◽

Can Huang ◽

Shu-Yun Liu

Keyword(s):

Case Report ◽

Sinus Thrombosis ◽

Cerebral Venous Sinus Thrombosis ◽

Venous Sinus ◽

Venous Sinus Thrombosis ◽

In Pregnancy

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Cerebral venous sinus thrombosis associated with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh211004104n ◽

2021 ◽

pp. 104-104

Author(s):

Dragan Nikolic ◽

Marijana Basta-Nikolic ◽

Vladimir Manojlovic ◽

Zeljko Zivanovic ◽

Sanja Vickovic ◽

...

Keyword(s):

Risk Factors ◽

Mortality Rate ◽

Severe Acute Respiratory Syndrome ◽

High Mortality ◽

Clinical Presentation ◽

Sinus Thrombosis ◽

Cerebral Venous Sinus Thrombosis ◽

Neurological Symptoms ◽

Venous Sinus ◽

Venous Sinus Thrombosis

Introduction/Objective. Coagulopathy induced by severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2) can be an underlying cause of cerebral venous sinus thrombosis (CVST), a less common type of stroke with a variable clinical presentation and high mortality rate. Objective: to present a series of CVST cases associated with SARS-CoV-2 infection. Methods. This retrospective study evaluated clinical, laboratory and radiological presentation, risk factors, barriers to diagnosis, treatment and outcome of patients with SARS-CoV-2 infection induced CVST. Results. The study comprised 6 patients diagnosed with COVID-19 induced CVST during the 18 months period. Majority (66.7%) had no significant risk factors for developing CVST. Median time from initial COVID-19 diagnosis to onset of neurologic deficit was 7 days (interquartile range 0.5-7 days). Clinical presentation comprised non specific neurological symptoms: headache (83.3%) and decreased consciousness (33.3%), together with elevated levels of D-dimer and inflammatory biomarkers. The transverse (n = 4 or 66.7%), superior sagittal sinuses (n = 3 or 50%) and sigmoid sinus (n = 2 or 33.3%) were most commonly affected. Five patients (83.3%) had minimal to no symptoms at discharge (mRS ? 2). In-hospital mortality in our current series was relatively high (16.7%). Conclusion. The high mortality rate of SARS-CoV-2-associated CVST urges clinicians to suspect CVST in patients with a history of COVID-19 infection presenting with non-specific neurological symptoms in order to provide proper treatment and prevent complications.

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