scholarly journals Correlation between placental location and development of preeclampsia

2019 ◽  
Vol 8 (11) ◽  
pp. 4155
Author(s):  
Prashaant Uikey ◽  
Vaishali Gurwani ◽  
Megha Tajne
Keyword(s):  
Prospective Study ◽  
Screening Test ◽  
Odds Ratio ◽  
Cost Effective ◽  
Antenatal Clinic ◽  
P Value ◽  
Singleton Pregnancy ◽  
Urine Albumin ◽  
Obstetrics And Gynaecology ◽  
A Prospective Study

Background: Preeclampsia occurs in presence of placenta. Blood supply distribution within the uterus is not similar in central versus lateral sites implicating that, the site of placenta is likely to have a profound effect on the pregnancy outcome. In the light of these observations, a prospective study was designed to find out if the lateral location of placenta as seen by ultrasound between 18-24 weeks of gestation can be used to predict the development of preeclampsia.Methods: This prospective study was conducted in the department of Obstetrics and Gynaecology in IGGMC, Nagpur between January 2017 and June 2018. Pregnant women, with singleton pregnancy and without any risk factor, attending the antenatal clinic were subjected to USG between 18-24 weeks of gestation. Accordingly, patients were divided into 2 groups, 51 with lateral placenta and 51 with central placenta. All 102 women were followed till term. The end point of the study was development of preeclampsia i.e. BP >140/90 and urine albumin >300 mg in 24 hours sample. The data obtained was analysed using appropriate statistical tests.Results: Out of 102 patients, 80.9% were from lateral placenta group and only 19.1% were from central placenta. Sensitivity of this as screening test for preeclampsia was 80.9% while specificity was 58%, Odds ratio being 5.875. In predicting preeclampsia, lateral placenta had a meaningful effect with p value <0.001.Conclusions: Placental laterality, as determined by USG between 18-24 weeks of gestation, is a simple and cost-effective screening test for development of preeclampsia.

scholarly journals Computed tomography scan findings in eclampsia: a prospective study

2018 ◽  
Vol 7 (11) ◽  
pp. 4432
Author(s):  
K. S. Raja Rajeswari ◽  
R. Niranjana
Keyword(s):  
Computed Tomography ◽  
Prospective Study ◽  
Ct Scan ◽  
Brain Infarction ◽  
Cortical Blindness ◽  
Obstetrics And Gynaecology ◽  
A Prospective Study ◽  
Ct Finding ◽  
Brain Haemorrhage ◽  
Tomography Scan

Background: Eclampsia is a leading cause of maternal death, with classical neurological symptoms that include headache, nausea, vomiting, cortical blindness, coma and convulsions. Computed tomography (CT) scan helps in diagnosing and management of eclampsia in pregnant women. The present study was done with the objective to analyse the findings of CT scan of brain in eclampsia, to identify the prevalence of neurovascular complications in these cases and to determine if these findings can be of value in determining the prognosis of this disorder.Methods: This was a prospective study done on 100 patients with eclampsia. All of the 100 patients were screened with CT scan brain at Institute of Obstetrics and Gynaecology, Egmore, Chennai during the period from August 2008 to August 2009. All the data were analyzed and compared between the groups of positive CT scan and negative CT scan observations.Results: Out of 100 patients, positive CT scan findings were noticed in 15 patients. Of them, 7 patients expired, and 8 patients survived after treatment. Of the expired patients (7), 5 of them expired due to brain haemorrhage, and 1 patient died with cerebral oedema and 1 with brain infarction. Cerebral odema (46%) was the most common positive CT finding.  Parietal region of brain was the most common (40%) affected area.Conclusions: CT scan of brain provides valuable information in determining the prognosis and the prevalence of neurovascular complications in Eclampsia.

scholarly journals Comparative assessment of fetomaternal outcome in twin pregnancy with singleton pregnancy at tertiary care centre

2017 ◽  
Vol 6 (6) ◽  
pp. 2395
Author(s):  
Divya Gupta ◽  
Premlata Mital ◽  
Bhanwar Singh Meena ◽  
Devendra Benwal ◽  
. Saumya ◽  
...  
Keyword(s):  
Twin Pregnancy ◽  
Tertiary Care ◽  
Comparative Assessment ◽  
P Value ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Singleton Pregnancy ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Twin Pregnancies

Background: Multiple pregnancy remains one of the highest risk situations for the mother, foetus and neonate despite recent advances in obstetrics, perinatal and neonatal care. Twin pregnancies have increased rates of obstetric and perinatal complications compared to singletons Objective of present study was comparative assessment of fetomaternal outcome in twin pregnancy with singleton pregnancy in Obstetrics and Gynaecology Department of S.M.S. Medical College, Jaipur.Methods: This was a hospital based, prospective observational study done in the Department of Obstetrics and Gynaecology. S.M.S. Medical College, Jaipur from April 2015 to March 2016. 150 women with twin pregnancy and 150 women with singleton pregnancies at gestation age of 28 weeks and above coming for delivery and consented for the study were included in the study. Women with chronic medical disorder or chronic hypertension were excluded from the study. Maternal and neonatal outcome recorded and analysed.Results: Occurrence of twin in our study was 2.82%. Risk of preterm labour was about nine times higher in twin pregnancies than the singleton (OR: 2.74, 95% CI; 1.4494-5.1884, P value 0.001). The risk of premature rupture of membrane was increased by 2.74 times in twin pregnancies (OR:2.74; 95% CI: 1.4494-5.1884, p value .001). There was 3-time increased risk of malpresentation (OR 3.14; CI:1.7184-5.7480, p value .00002) and 2.28 times increase in hypertensive disorder (OR 2.28; 95% CI: 1.0727-4.8823, p value .03) in twin pregnancies. The risk of asphyxia and septicaemia was 2.5 times more in twins.Conclusions: Twin pregnancy is a high-risk pregnancy with more complications in mother and foetus and is a great challenge for obstetrician. So, it should be managed carefully at tertiary care centre to reduce the maternal and perinatal mortality and morbidity.

ESTIMATION OF FETAL WEIGHT BY CLINICAL METHODS AND ULTRASOUND AND CORRELATING ITS ACCURACY WITH ACTUAL BIRTH WEIGHT IN TERM PREGNANCIES AT ANMMCH, GAYA, BIHAR

2021 ◽  
pp. 17-19
Author(s):  
Kumari Ragini ◽  
Amit Kumar ◽  
Reena Kumari ◽  
Debarshi Jana
Keyword(s):  
Birth Weight ◽  
Prospective Study ◽  
Fetal Weight ◽  
Term Pregnancy ◽  
Abdominal Girth ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Clinical Methods ◽  
Fetal Birth Weight ◽  
A Prospective Study

Objective:This study was to estimate the fetal weight in term pregnancy by clinical methods and ultrasound and to compare the results with actual birth weight (ABW). Material and Methods:This study was conducted at Department of Obstetrics and Gynaecology, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar from December 2019 to May 2020. It was a prospective study covering 200 pregnant women at term gestation. Results: Estimated birth weight by abdominal girth × symphysis fundal height (AG × SFH) formula was closest to the ABW (P = 0.060), as compared to the estimated birth weight by Johnson's formula (P = 0.000) and Hadlock's formula (P = 0.000). Therefore, of the three formulae studied, AG × SFH formula had better predictive value as compared to Johnson's and Hadlock's formulae. The accuracy of AG × SFH (Insler's formula) for estimating the fetal weight at term was found to be comparable to Hadlock's formula (P= 0.104). Conclusion: Clinical estimation of birth weight denitely has a role in the management of labor and delivery. AG × SFH is a simple, easy, costeffective, and universally applicable method to predict fetal birth weight which can be used even by paramedics like midwives and also in centers where ultrasound is not available.

scholarly journals Spectrum of cutaneous manifestations in Wilson’s disease in children in a tertiary care center in South India: a prospective study

2017 ◽  
Vol 4 (6) ◽  
pp. 2060
Author(s):  
Karrunya K. J. ◽  
Sumathi Bavanandam ◽  
Nirmala Dheivamani ◽  
Vijayabhaskhar C. Reddy ◽  
Manoharan K.
Keyword(s):  
Portal Hypertension ◽  
Skin Biopsy ◽  
Prospective Study ◽  
Wilson’S Disease ◽  
Wilson's Disease ◽  
P Value ◽  
Indian Children ◽  
Cutaneous Manifestations ◽  
Mucosal Involvement ◽  
A Prospective Study

Background: Wilson’s disease in children is the most common inherited disorder of copper metabolism in India with varied clinical manifestations secondary to deposition of copper in various organs including skin. Methods: The aim of the study was to study various cutaneous manifestations of Wilson’s disease in south Indian children. A prospective study for a period of one year was conducted at Dermatology and Pediatric Gastroenterology clinic in Government Rajiv Gandhi Hospital, Chennai. Clinical, demographic details, various cutaneous manifestations and results of skin biopsy were analysed.  Results: Out of the total 30 children with Wilson’s disease, 93.3% had at least one cutaneous, mucosal, hair or nail findings but not statistically significant between naive and on treatment group. Cutaneous findings, mucosal involvement, hair changes and nail findings were observed in 90%, 36.7%, 46.7% and 60% respectively. Cutaneous findings were more common in liver disease (P value<0.05). Xerosis was the most common cutaneous manifestation seen in 63.3% patients, followed by pigmentation in 36.7% and infection in 30%.  KF ring was noted in 53.3%. Icterus and pruritus were seen in one fifth of study children and majority had portal hypertension. Vascular changes like spider nevi, purpura and other features of portal hypertension were noted in 16.6% of study population. Trichomegaly was one of the common hair manifestation found in 9 (30% especially in children already on treatment (p value <0.05). There was no evidence of stainable copper on skin biopsy. Conclusions: The physicians should be aware of various cutaneous manifestations of Wilson’s disease in children.

scholarly journals Sustained transanorectal cryogenic treatment of hemorrhoids with the cryocure device: a prospective study

2019 ◽  
Vol 6 (4) ◽  
pp. 1036
Author(s):  
Rajah Vijay Kumar ◽  
Hendrik R. Franke
Keyword(s):  
Treatment Outcome ◽  
Sustained Release ◽  
Prospective Study ◽  
Cryogenic Treatment ◽  
Cost Effective ◽  
Effective Solution ◽  
Choice Of Treatment ◽  
Effective Choice ◽  
A New Technique ◽  
A Prospective Study

Background: Globally about 330 million people suffer from hemorrhoids at some time during their lives.  About 1.2 million new cases are reported annually, it is not discussed freely and  a simple, safe and cost effective solution is yet to be proposed. The authors studied a new technique called Transanorectal Vasoconstriction as a possible treatment of grade 1, 2 and 3 hemorrhoids.Methods: The study randomly recruited 1591 patients suffering from grade 1 to 3 hemorrhoids in Europe and India and subjected them to Transanorectal Cryogenic Vasoconstriction technique using a device called Cryocure that provides sustained release cooling of hemorrhoids leading to vasoconstriction and shrinkage. The technique was applied between 7 and 15 days and patients were assessed after 3 months.Results: The treatment outcome of 1591 patients (M:F 962:629) recruited randomly, showed that 86.12% were practically symptom free after 7 to 14 days of the treatment, and during the assessment after three months. 6.36% of the treated patients reported that one or more symptoms of itching and pain persisted but were not bleeding after the treatment period of 7 to 14 days. A few patients, 3.11% had reported that they had no benefit whatsoever from the treatment. All patients were followed for a period of 9 months. However, it was found that 4.45% of patients had various types of recurrences including bleeding.Conclusions: The present study concludes that Transanorectal Cryogenic Vasoconstriction technique using Cryocure can be a simple, safe and cost effective choice of treatment in uncomplicated grade 1, 2 and 3 hemorrhoids.

scholarly journals A prospective study to find out the most cost effective preoperative prophylactic antibiotic regime in elective abdominal routine surgeries

2016 ◽  
Vol 4 (2) ◽  
pp. 157-163
Author(s):  
Dr. Narendra N Ganguly ◽  
◽  
Dr. Rituparna Phukan Ray ◽  
Dr. M Lahka ◽  
Dr Ms Aisha Siddiqui ◽  
...  
Keyword(s):  
Prospective Study ◽  
Prophylactic Antibiotic ◽  
Cost Effective ◽  
Antibiotic Regime ◽  
A Prospective Study

scholarly journals Reflexões sobre o trauma cardiovascular civil a partir de um estudo prospectivo de 1000 casos atendidos em um centro de trauma de nível I: a prospective study from 1000 cases

2008 ◽  
Vol 35 (3) ◽  
pp. 162-167 ◽  
Author(s):  
Ricardo Costa-Val ◽  
Sérgio Figueiredo Campos-Christo ◽  
Wilson Luiz Abrantes ◽  
Marcelo Barroca Campos-Christo ◽  
Maria Cristina Marques ◽  
...  
Keyword(s):  
Prospective Study ◽  
Odds Ratio ◽  
A Prospective Study

OBJETIVO: Analisar os dados referentes a uma grande série de casos de traumas cardiovasculares exclusivamente civil operados em um único centro de trauma brasileiro. MÉTODO: Trata-se de um estudo de coorte, prospectivo, descritivo e analítico registrados entre os anos de 1998 - 2005. RESULTADOS: No período foram operados 1000 casos que acometeram principalmente homens jovens devido a armas de fogo, armas brancas/vidros e trauma contuso e cuja topografia das lesões se deu na seguinte ordem: abdominais, cervicais, torácicas e extremidades. As três síndromes mais comuns a admissão foram: hemorrágica, isquêmica e hemorrágica/isquêmica. No entanto, 34.6% dos pacientes estavam em choque hipovolêmico grave e em 85% da casuística havia lesões não cardiovasculares associadas. A maioria dos pacientes foi submetida a tratamento cirúrgico sem propedêutica específica, mas 14% destes foram reoperados devido à síndrome compartimental, trombose aguda e/ou hemorragia grave. A taxa de amputação foi de 5.5% e da mortalidade de 7.5%, estando correlacionada com choque hipovolêmico grave ou síndrome da resposta inflamatória sistêmica. Lesões CCV isoladas ocorreram em 15% dos casos com taxa de letalidade global de 41%, sendo 22% venosa, 47% arterial e 81% cardíaca, proporcionando diferença significativa entre lesões cardíacas versus arteriais e venosas associadas (p = 0,01; odds ratio de 7.37) e lesões arteriais versus venosas (p = 0,01; odds ratio de 3.17). CONCLUSÃO: Esta grande série de casos demonstrou ser o homem jovem o mais acometido devido principalmente à violência interpessoal e os acidentes automobilísticos, que envolvem na maioria das vezes as extremidades, associadas com lesões em outros órgãos ou sistemas. Os fatores preditivos de mau prognóstico foram choque hipovolêmico, lesão de grandes vasos arteriais e lesão cardíaca.

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