scholarly journals A prospective study to compare levonogestrol intrauterine system and trans-cervical resection of endometrium for treatment of abnormal uterine bleeding

2019 ◽  
Vol 8 (12) ◽  
pp. 4919
Author(s):  
Kishorkumar V. Hol ◽  
Shraddha S. Shastri ◽  
Shilpa S. Magar ◽  
Sameer P. Darawade
Keyword(s):  
Adverse Effects ◽  
Blood Loss ◽  
User Satisfaction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Bipolar Electrode ◽  
Loss Assessment ◽  
Adnexal Pathology ◽  
Acceptance Rates ◽  
A Prospective Study

Background: This article is a study comparing the two most accepted forms of treatment for abnormal uterine bleeding - levonorgestrol intrauterine treatment and transcervical resection of endometrium, with regards to its acceptability, efficacy, adverse effects and user satisfaction. Aim of this study was to compare the acceptability, efficacy, adverse effects and user satisfaction of LNG-IUS and TCRE for treatment for AUB.Methods: A prospective observational study conducted in SKNMC and GH. Forty-nine women with abnormal uterine bleeding after hysteroscopic evaluation were included in this study; where 17 opted for LNG-IUS; 32 opted for TCRE with bipolar electrode. 15 patients in LNG-IUS group and 28 pts in TCRE group completed follow up. Menstrual pattern, pictorial blood loss assessment chart score, adverse effects, acceptability, satisfaction and reason for discontinuation were recorded at 6 weeks, 6 months and 12 months after the procedure. Prior to LNG-IUS insertion or endometrial ablation, endometrial and cervical pathology were excluded by D and C and cervical smear, respectively. TVUS was used to exclude possible causes of menorrhagia, including myomas and endometrial polyp as well as adnexal pathology. LNG-IUS insertion was performed as an office procedure one day after cessation of menstrual bleeding with a negative urine pregnancy test.Results: Menstrual blood loss reductions in TCRE and LNG-IUS groups were by 85.7% and 87.6% respectively after a year. Amenorrhoea was more common in TCRE group while spotting and systemic effects were more common in LNG-IUS group. Satisfaction and acceptance rates are higher in TCRE group.Conclusions: The TCRE and LNG-IUS are equally effective in reducing bleeding in AUB patients. Acceptance and satisfaction are better with TCRE, as a modality of treatment for AUB.

scholarly journals A CASE REPORT ON EFFECTIVE MANAGEMENT OF ASRIGDARA

2020 ◽  
pp. 106-111
Author(s):  
Khushboo Jha ◽  
K. Bharathi ◽  
Sonu
Keyword(s):  
Blood Loss ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Menstrual Bleeding ◽  
Menstrual Blood Loss ◽  
Loss Assessment ◽  
Sf 36 ◽  
Before And After ◽  
Normal Menstrual Cycle

Any uterine bleeding outside the normal volume, duration, regularity or frequency is considered as abnormal uterine bleeding (AUB). Nearly thirty percent of all gynaecological outpatient attendants are for AUB. Abnormal menstrual bleeding pattern have been traditionally expressed by terms like menorrhagia, metrorrhagia, polymenorrhagia & oligomenorrhoea. Normal menstrual cycle interval is 28 days (21-35 days), menstrual flow duration 4-5 days and normal menstrual blood loss should be 35ml (20-80 ml). Any deviation in the above criteria comes under abnormal uterine bleeding, means excessive amount of bleeding or increased duration of bleeding during menstruation or both termed as AUB. In Ayurveda same is described as Pradara. A female patient aged 22 years visited OPD of Prasuti Tantra and Stri Roga department of NIA, with complaints of heavy menstrual bleeding and prolonged menstrual bleeding more than seven days since six months. Pictorial blood loss assessment chart was used to assess the amount of blood loss before and after treatment. SF-36 questionnaire was assessed to know the improvement in quality of life. Patient was given Kutajashtakaleha 10 gm BD with cows milk.

A Study to Analyze the Efficacy of Levonorgestrel Intrauterine System in the Management of Abnormal Uterine Bleeding among Urban Indian Women

2017 ◽  
Vol 5 (1) ◽  
pp. 19-22
Author(s):  
Bijit Chowdhury ◽  
Poushali Sanyal ◽  
Anshu Gupta ◽  
Bidisha Roychoudhury ◽  
MMS Zoha
Keyword(s):  
Blood Loss ◽  
Hemoglobin Concentration ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Medical Sciences ◽  
Loss Assessment ◽  
Indian Women ◽  
Gynecology And Obstetrics ◽  
Level Of Satisfaction ◽  
Urban Indian

ABSTRACT Objective The study tried to analyze the efficacy of levonorgestrel intrauterine system (LNGIUS) for the treatment of heavy menstrual bleeding in the urban and suburban Indian women. Materials and methods The present study was conducted in the Department of Gynecology and Obstetrics, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, Kolkata, over a period of 1 year. A total of 20 patients suffering from abnormal uterine bleeding in the age group of 20 to 45 years were recruited in this study. The LNGIUS was inserted in all the women and they were followed up at the end of 3, 6, and 12 months. All subjects completed 1 year duration of follow-up. We used the Student’s paired t-test to evaluate the reduction in the menstrual blood loss, passage of clots, and increase in hemoglobin concentration at each point from the baseline. Results At the end of 6 months, most (90%) of the women had an acceptable bleeding, with 10% having amenorrhea (pictorial blood-loss assessment chart score 0). Statistically significant improvement in the hemoglobin level was observed at the end of 3, 6, and 12 months postinsertion. The level of satisfaction increased steadily with time. Conclusion Levonorgestrel intrauterine system is an effective reversible treatment for menorrhagia. Levonorgestrel intrauterine system can be used as an effective alternative to hysterectomy in the future in the urban and suburban affluent Indian women. How to cite this article Gupta A, Roychoudhury B, Sanyal P, Chowdhury B, Zoha MMS. A Study to Analyze the Efficacy of Levonorgestrel Intrauterine System in the Management of Abnormal Uterine Bleeding among Urban Indian Women. J South Asian Feder Menopause Soc 2017;5(1):19-22.

scholarly journals Evaluation of the Role of Ormeloxifene in Abnormal Uterine Bleeding

2017 ◽  
Vol 5 (2) ◽  
pp. 107-110
Author(s):  
Ritu Sharma ◽  
Savita R Singhal
Keyword(s):  
Side Effects ◽  
Blood Loss ◽  
Endometrial Thickness ◽  
Hormonal Treatment ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Hemoglobin Level ◽  
P Value ◽  
Loss Assessment

ABSTRACT Aim This is a prospective study to find the effect of ormeloxifene on menstrual blood loss and its side effects in patients with abnormal uterine bleeding (AUB). Materials and methods Fifty women in the age group of 30 to 52 years with AUB were enrolled in the study. After baseline assessment, each patient was given 60 mg of ormeloxifene orally twice a week for first 3 months, then once a week for the next 3 months. The patients were followed up after 1, 3, and 6 months. The effect of ormeloxifene was evaluated by a change in the pictorial blood loss assessment chart (PBAC) score, passage of clots during menstruation, hemoglobin level, endometrial thickness (ET), and dysmenorrhea. Side effects of the drug were also noted at each visit; p-value < 0.05 was taken as significant. Results There was statistically significant reduction in median PBAC score from baseline 360 to 113, 73, and 41.5 after 1, 3, and 6 months. There was significant reduction in ET, passage of clots, and dysmenorrhea at each visit. Mean hemoglobin level increased significantly by 1.56 gm% after 6 months treatment. Adverse effects included amenorrhea (28%), ovarian cyst (11.3%), nausea (4.5%), headache (2%), and weight gain (4.5%). There was no major side effect requiring termination of treatment. Conclusion Ormeloxifene is a safe and efficacious alternative for medical therapy in the management of AUB. Clinical significance Ormeloxifene can be used in women with AUB to avoid the side effects of hormonal treatment and unnecessary hysterectomies. How to cite this article Sharma R, Singhal SR. Evaluation of the Role of Ormeloxifene in Abnormal Uterine Bleeding. J South Asian Feder Menopause Soc 2017;5(2):107-110.

Improvement of Symptoms After Hysteroscopic  Isthmoplasty in Women with Abnormal Uterine Bleeding and Expected Pregnancy: A Prospective Study

2021 ◽  
Author(s):  
Anh Duy Nguyen ◽  
Ha Thi Thu Nguyen ◽  
Giang Thi Tra Giang ◽  
Thuong Thi Huyen Phan ◽  
Dat Tuan Do ◽  
...  
Keyword(s):  
Prospective Study ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
A Prospective Study

Association of cesarean scar defect with abnormal uterine bleeding: The results of a prospective study

2020 ◽  
Vol 244 ◽  
pp. 134-140 ◽  
Author(s):  
Riitta M. Antila ◽  
Johanna U. Mäenpää ◽  
Heini S. Huhtala ◽  
Eija I. Tomás ◽  
Synnöve M. Staff
Keyword(s):  
Prospective Study ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Cesarean Scar ◽  
A Prospective Study

scholarly journals Comparative Study of Desogestrel- Containing Oral Contraceptive and Levonorgestrel- Containing Oral Contraceptive in Dysfunctional Uterine Bleeding

2020 ◽  
Vol 11 (4) ◽  
pp. 5678-5684
Author(s):  
Swathi Suresh ◽  
Mariya Els Johny ◽  
Kiruba Shankari ◽  
Ahamed Irshath U ◽  
Yokesh M ◽  
...  
Keyword(s):  
Weight Gain ◽  
Oral Contraceptive ◽  
Side Effects ◽  
Menstrual Cycle ◽  
Blood Loss ◽  
Ethinyl Estradiol ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Dysfunctional Uterine Bleeding ◽  
Group D

Dysfunctional uterine bleeding is a type of abnormal uterine bleeding where vaginal bleeding occurs outside of the menstrual cycle in the absence of any known pelvic pathology. Dysfunctional uterine bleeding can be treated safely with hormone therapy. Combined oral contraceptives help in increased menstrual cycle regularity and decreased blood loss. In this study, a reliable drug for the dysfunctional uterine bleeding with maximum effectiveness and minimal side effects were assessed. This study was conducted on 120 cases of dysfunctional uterine bleeding. Patients who were diagnosed with dysfunctional uterine bleeding were randomly assigned into two groups. Group D and group L included patients who were given Ethinyl estradiol 0.02mg + desogestrel 0.15mg and Ethinyl estradiol 0.03mg + levonorgestrel 0.15mg respectively for the four consecutive 28- day cycles. Menstrual blood loss was assessed using the pictorial blood assessment chart (PBAC) score on 2nd and 4th months of recruitment. Side effects such as weight gain, acne and headache were assessed in both groups. This study shows 56.68% reduction in mean PBAC score in 2 months in desogestrel group whereas only 44.96% reduction in levonorgestrel group and 79.87% reduction in mean PBAC score in desogestrel group in 4 months whereas only 74.46% reduction in levonorgestrel group. Side effects like weight gain, acne and headache were more prominent in the levonorgestrel group than desogestrel group. Desogestrel containing combined oral contraceptive can be a useful and safe treatment for dysfunctional uterine bleeding.

scholarly journals A Literary Review of AsrigdarainAyurvedw.s.r. to Menometrorrhagia

2021 ◽  
Vol 04 (11) ◽  
pp. 97-99
Author(s):  
Sonu Kumari ◽  
Mahesh Dixit ◽  
Narendra Kumar Meena
Keyword(s):  
Menstrual Cycle ◽  
Blood Loss ◽  
Abnormal Uterine Bleeding ◽  
Causative Factor ◽  
Uterine Bleeding ◽  
Massive Blood Loss ◽  
Result Management

In PrasutitantraOPD, Menometrorrhagia is the most common gynaecological illness. It is a symptom that can be detected in the majority of gynecological issues. The irregular, massive blood loss per vaginum is a symptom of abnormal uterine bleeding. Bleeding in excess of regular amounts and for a longer period of time during the menstrual cycle. Abnormal uterine bleeding is known as Asrigdara in Ayurvedic samhitas, which implies pradirana(extreme excretion) of raja (menses) per vaginum. The causative factor or Dosa In Asrigdarais Vayu, and the vitiated Dhatu Or Dusya is Rakta(blood), or blood is also vitiated. Because the qualities of rakta and pittaare so similar, vitiating Raktawould aggravate pitta as well. As a result, management should be centered on the usage of medications with Kashaya Rasa and Pittashamak Guna.Due to its Stambhanafeature, Kashaya rasais mostly used to treat bleeding symptoms.There is loss of Rakta Dhatu, so we use the drugs and diet that increases Rakta Dhatu.Management mainly based on the principle of Raktastambhakaand Raktavardhaka.

scholarly journals Clinico-histopathological and ultrasonographic correlation of abnormal uterine bleeding in perimenopausal and postmenopausal women

2021 ◽  
Vol 10 (6) ◽  
pp. 2408
Author(s):  
Sharanya . ◽  
Julie Thomas
Keyword(s):  
Data Entry ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Common Finding ◽  
Ethical Review ◽  
Histopathological Correlation ◽  
Endometrial Pattern ◽  
Endometrial Hyperplasia With Atypia ◽  
Observational Group ◽  
A Prospective Study

Background: Abnormal uterine bleeding (AUB) accounts for one of the most common gynaecological problem, almost one third of total cases. The study was a prospective study done from December 2017 to November 2019. The histopathological reports of endometrial pattern as well as that of hysterectomy specimens were correlated with clinical diagnosis and ultrasonographic findings. The main objective was to study the correlation between clinical, ultrasonographic and histopathological correlation of AUB in perimenopausal, menopausal and postmenopausal women.Methods: Formal Permission was obtained from the administrator of St. Philomena’s hospital. Ethical clearance was obtained from institutional ethical review board of St. Philomena’s hospital. Informed consent was obtained from observational group and confidentiality was assured.  Data entry and analyses was done using the Statistical Package for Social Sciences (SPSS) for Windows software (version 20.0; SPSS Inc, Chicago).Results: A total number of 165 cases were studied. Maximum women were in the age group of 40-55 years 87.27%. Most common presentation of abnormal uterine bleeding is menorrhagia which accounts for 72.7% of women (120 women). The most common finding noted in USG was fibroid uterus which accounts for 44.2% of women (73 women). Most commonly observed histological pattern noted were proliferative (62.4%) followed by secretory endometrium (8.5%) and simple endometrial hyperplasia with atypia (8.5%).Conclusions: In conclusion, AUB is one of the most common condition for which patients seek advice in the gynaecological outpatient department. Analysis of histopathology of endometrium in abnormal uterine bleeding helps in management of patients and to know the pathological incidence of structural causes in AUB prior to surgery.

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