scholarly journals Connective tissue disorders in pregnancy: maternal and fetal perspective

2020 ◽  
Vol 9 (3) ◽  
pp. 1124
Author(s):  
Nehul Jha ◽  
Hemangi K. Chaudhari
Keyword(s):  
Connective Tissue ◽  
Stress Test ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Outpatient Department ◽  
Connective Tissue Disorders ◽  
Intensive Care Admission ◽  
Biophysical Profile ◽  
King Edward Memorial Hospital ◽  
In Pregnancy

Background: The objective of this study was to study maternal and fetal outcome in connective tissue disorders in pregnancy.Methods: This was a retrospective type of observational study done in department of obstetrics and gynecology and department of rheumatology at a King Edward Memorial hospital over a period of 1.5 years. 48 women were included in this study after informed consent. All these women presented with collagen disorders to ANC outpatient department or to rheumatology outpatient department or in emergency. All postpartum patients having connective tissue disorders not recruited during ANC were also included in this study after taking their written, informed and valid consent.Results: Connective tissue disorders are associated with multiple voluntary and involuntary abortions as well as intrauterine fetal deaths. Even in those women having live births, many undergo cesarean sections due to various indications like fetal distress, poor biophysical profile, non-reassuring non stress test etc. Neonates born to mothers with connective tissue disorders are growth restricted and many of them need intensive care admission. Also, these women were found to have multiple associated medical comorbidities in pregnancy.Conclusions: The data collected and the results arrived upon should help contribute significant literature regarding collagen disorders in pregnancy and help in better fetal and maternal management during pregnancy.

scholarly journals Role of modified biophysical profile and cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies

2018 ◽  
Vol 7 (3) ◽  
pp. 1104
Author(s):  
Urvashi . ◽  
Sujani B. K. ◽  
Krishna Sai Sushma
Keyword(s):  
High Risk ◽  
Perinatal Outcome ◽  
Pulsatility Index ◽  
Stress Test ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Low Risk ◽  
Cerebroplacental Ratio ◽  
Biophysical Profile

Background: The timely detection of morbid changes in the fetal status followed by adequate interventions to avoid death or disability is one of the most important objectives of prenatal care. Objective of present study was to Comparing the role of modified biophysical profile and the cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies.Methods: Two hundred and seventy three singleton pregnant women were included in this study. Following routine examination, amniotic fluid index, pulsatility index of middle cerebral artery and pulsatility index of umbilical artery, uterine artery mean pulsatility index were evaluated. Non stress test (NST) was done. Modified biophysical profile (MBPP) and Cerebroplacental ratio (CPR in percentile) was generated. Caeserean section because of Fetal distress, birth weight <10th centile, 5min APGAR <7, NICU stay >24hours were used in evaluating the perinatal outcome.Results: Out of 273 cases, 107 cases had poor perinatal outcome. Out of 107 cases, 35.5% cases were IUGR, 39.2% cases underwent caesarean section in view of fetal distress, 39.2% babies had 5min APGAR <7 and 32.7% babies had stayed in NICU for >24hrs. In high risk cases, poor perinatal outcome was seen in 45.5% pregnancies and 36.7% in low risk pregnancies. Sixty seven percent of these cases had abnormal modified biophysical profile and only 7.4% cases had cerebroplacental ratio <1.Conclusions: Modified biophysical profile was proved to be more significant than cerebroplacental ratio in prediction of perinatal outcome. 

scholarly journals FETAL BIOPHYSICAL PROFILE

2010 ◽  
Vol 17 (04) ◽  
pp. 670-675
Author(s):  
BUSHRA BANO ◽  
UZMA HUSSAIN ◽  
BUSHRA ZAHID
Keyword(s):  
Caesarean Section ◽  
Apgar Score ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Fetal Hypoxia ◽  
Effective Technique ◽  
Biophysical Profile ◽  
Fetal Movements ◽  
History Of ◽  
One Year

To evaluate fetal Biophysical Profile as an effective technique for the assessment of fetal condition and to improve fetal outcome by early detection of fetal hypoxia. Design: Co relational study: Place and Duration of Study: The study was carried out for a period of one year from Oct 2004-Oct 2005 at Obstetrics and Gynecology Department of Fatima memorial hospital Lahore. Patients and Methods: All patientswith history of sluggish fetal movements and clinical suspicion of IUGR, were underwent BPP from 32-42weeks. 100 patients were selected and their BPP score was recorded and were followed till delivery. Those who went into spontaneous labor and who were induced monitored during labor and at any sign of fetal distress immediate caesarean section performed. APGAR score of newborn was noted at one and five minutes and those having poor APGAR score were resuscitated and were followed till one week after delivery. APGAR score was compared with BPP score. Results: During this study 100 BPP were performed. 34patients were primigravidas and 66 were multigravidas. Among 100 patients 73had a BPP score of 9-10/10, 21 patients had a score of 7-8/10 and 6 patients had 4-6/10.In 2 patients with 4/10score emergency caesarean section led to the delivery of neonates with APGAR score of 8 at 5 minutes. Majority of patients with normal BPS of 8-9/10 had good APGAR score of 7- 8/10.Only 8 patients having BPP of 9-10/10 had poor APGAR score 6/10 or <6/10. Conclusion: The fetal BPP appears to be an effective technique for assessment of fetal condition.

scholarly journals True Umbilical Cord Knot Leading to Fetal Distress – an Obstetric Emergency

2021 ◽  
pp. 60-63
Author(s):  
Twisha Patel ◽  
Sandhya Pajai
Keyword(s):  
Umbilical Cord ◽  
Stress Test ◽  
Birth Asphyxia ◽  
Rare Condition ◽  
Fetal Distress ◽  
Well Being ◽  
Fetal Outcome ◽  
Fetal Movement ◽  
Normal Limits ◽  
Fetal Movements

Background: Umbilical cord true knot is a rare condition which affects about 1% of all pregnancies. Though the incidence is lower, it often goes undetected in antenatal period despite the availability of prenatal sonography and may lead to a compromised fetal outcome as presented in this case. In this case the presence of true knot of umbilical cord was missed despite routine sonography done just 1 week prior to delivery, when patient presented to casualty with complains of decreased fetal movements since 24 hours. This modality is said to be associated with adverse fetal outcome such as birth asphyxia or in adverse cases intra uterine fetal demise. Risk factors include long cord, polyhydramnios, small sized fetus, etc. Case Summary: 27 years old gravida two, para two, with 1 live issue with k/c/o hypothyroidism with previous lesions came with complaints of decreased fetal movement since 24 hours at 36 weeks 3 days of gestational period. The patient recorded regular ANC checkups and routine investigations within normal limits. Her USG scan done at 34.2 wks showing single loop of cord around neck and normal doppler findings. On examination her vitals were normal .Her abdominal examination showed uterus of 34 wks size, longitudinal lie, cephalic presentation and irritable with mild contractions present with scar tenderness . Her FHS were present/irregular/112 bpm with less variability. On p/v examination os was admitting tip of finger, cervix soft, 25% effaced, station high up, presenting part vertex, membrane present. She was advised admission and a cardio-tocography (CTG) was done which showed recurrent deep atypical variable decelerations with decreased beat to beat variability. An emergent cesarean section was taken. Newborn was a female diagnosed with true umbilical cord knot, 2 cm away from fetal insertion with cord length of 84 cm. The baby was shifted to NICU in view of respiratory distress. Conclusion: Despite of modern day ultrasonography and Doppler studies, true umbilical cord knot still remains a lesser diagnosed entity and so every pregnant patients should be monitored carefully with a watch for daily fetal movement count (DFMC)and weekly non stress test (NST) for fetal well being.

scholarly journals Biophysical profile and modified biophysical profile in predicting the fetal outcome

2018 ◽  
Vol 7 (9) ◽  
pp. 3516
Author(s):  
V. G. Vanamala ◽  
Aruna Rachel ◽  
Sushil Pakyanadhan ◽  
Sudheep Abraham P.
Keyword(s):  
Amniotic Fluid ◽  
Stress Test ◽  
Well Being ◽  
Fetal Outcome ◽  
Heart Beat ◽  
Amniotic Fluid Index ◽  
Uterine Contractions ◽  
Beat Pattern ◽  
Biophysical Profile ◽  
Fetal Movements

Background: Baby’s well-being in utero is often done by using a cardiotocograph (CTG) machine, which assesses the baby’s heart beat pattern as well as the mother’s uterine contractions. However, lowered fetal movements sometimes may be fatal for the baby. Thus, the biophysical and the modified biophysical profile have been introduced.Methods: 242 patients with over 34 weeks of gestation and with one or more risk factors were included in the study. After taking the demographic details, the patients were subjected to detailed physical and clinical evaluation. Modified BPP was done on all the patients. Index of acute fetal hypoxia the NST was done along with the cardiotocograph (CTG). Amniotic fluid volume was calculated.Results: According to the fetal non-stress test, majority of the patients (70.7%) were reactive while 29.3% were non-reactive. Most of the patients had an amniotic fluid index in the normal range i.e. between 8 -<25, 18.6%) had an AFI value of <6 cm while 13.6% had between 6 - <8. Among the babies with reactive NST, non-reactive NST and AFI ≤5, the most common outcome was low birth weight.  APGAR score <7 was observed in 11.1%, 13.1%, 20% among Reactive NST, Non-reactive NST and AFI ≤5 respectively.Conclusions: Present study shows that BPP and MBPP are both comparable to each other, therefore, MBPP, being an easier test can be substituted for BPP.

scholarly journals Fever in pregnancy and its maternal and fetal outcomes

2017 ◽  
Vol 6 (12) ◽  
pp. 5523
Author(s):  
Vibha S. More
Keyword(s):  
Tract Infection ◽  
Cohort Analysis ◽  
Tertiary Care ◽  
Fetal Distress ◽  
First Trimester ◽  
Fetal Outcome ◽  
Third Trimester ◽  
Tertiary Care Centre ◽  
Fetal Outcomes ◽  
In Pregnancy

Background: Contemporary obstetrics has witnessed improved maternal and fetal outcomes, owing to several advances. Any source of maternal hyperthermia that results in significant core temperature increase (>38.9°C), could potentially affect the fetus.  Hence a study was planned to know the effect of fever on maternal and fetal outcome.Methods: This was a retrospective cohort analysis of case-records, of patients admitted in the Department of Obstetrics and Gynecology at tertiary care centre, Mumbai, between May 2007 and October 2009. The main parameters of assessment included incidence of fever in pregnancy, causes of fever, effect of episode(s) of fever on maternal and fetal outcomes, effect of specific infection on maternal and fetal outcomes, impact of fever on antepartum, intrapartum and postpartum phasesResults: The incidence of fever was 10.5%. the common cause of fever was malaria (15%), urinary tract infection (14%), viral (14%), respiratory tract infection (18%), and typhoid (7%). Seventy eight percent had fever in third trimester. The most common antenatal complication observed was preterm (13%), premature rupture of membrane (12%), oligohydramnios (8%), intrauterine growth retardation (26%). The rate of LSCS was 13% in study group and the most common indication was fetal distress and meconium stained amniotic fluid.Conclusions: In the present study on fever during pregnancy and its maternal and fetal outcomes, fever was associated with a definite impact on maternal and fetal outcomes. Preterm and IUGR were the most common fetal complications. Duration of fever was linearly associated with poor outcomes. Different causes of fever also had different impact on maternal and fetal outcome. Preterm IUGR, MSAF were more common with malaria and tuberculosis. Abortion was more commonly seen in first trimester fever, whereas preterm, PROM in the third trimester fever. Hence it is suggested that fever during pregnancy needs to be promptly investigated and treated to have a better outcome.

Connective Tissue Disorders in Pregnancy

2019 ◽  
Vol 37 (1) ◽  
pp. 121-129 ◽  
Author(s):  
Sophia L. Ryan ◽  
Shamik Bhattacharyya
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disorders ◽  
In Pregnancy
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