scholarly journals Predictors of poor glycemic control in type 2 diabetic patients in South Indian population

2018 ◽  
Vol 6 (2) ◽  
pp. 545
Author(s):  
Pushpita De ◽  
Shaheen Banu ◽  
Diviya Muthukumar
Keyword(s):  
Glycemic Control ◽  
Blood Sugar ◽  
Glucose Control ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
South Indian Population ◽  
Type 2 Diabetic Patients ◽  
South Indian ◽  
Type 2 Diabetic

Background: The aim of this study is to shed light on the patients ‘knowledge, expectations and attitudes with regards to glucose control, and to understand the barriers to achieving good glucose control among south Indian patients with type 2 diabetes.Methods: A cross-sectional study was conducted among 76 type 2 diabetic patients in this study. Patients’ information such as sociodemographic characteristics, family history of diabetes, diabetes duration, medication adherence, dietary pattern, physical activity was obtained through interview. Anthropometric details were noted during the interview. All available last readings for fasting blood sugar, post prandial blood sugar and glycosylated hemoglobin were abstracted from patients’ records.Results: A total of 76 patients were enrolled in the study. The overall mean (SD) duration of the disease was 9±7.02 years. 63% had HbA1c ≥7%, which is categorized as a poor glycemic control. 43% of the subjects had poor glucose control who did not follow healthy eating plans. 84% of the patients did participate in physical exercise but did not follow as recommended. 67% of the patients have poor knowledge about glucose control.Conclusions: The main results indicate that glycemic control in type 2 diabetes is generally poor. Longer duration of diabetes and not adherent to diabetes self-care management behaviors were associated with poor glycemic control. Therefore, a balanced approach to improve awareness about diabetes and its control both among patients and the medical fraternity is urgent need of the hour in India.

scholarly journals Blood pressure, lipid profile and glycemic control among type-2 diabetic patients in North Kerala

2021 ◽  
Author(s):  
Liji Kavuparambil ◽  
Ashok Kumar Pammi ◽  
Jithesh Tharayil Kattil ◽  
Santha Kaliyaperumal ◽  
Shifa Kollathodi
Keyword(s):  
Glycemic Control ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Blood Sugar ◽  
Significant Positive Correlation ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Background: Glycemic control, lipid control and other modifiable risk factor, is very important to prevent complications of type 2 diabetes. The objective of this study was to analyze glycemic control, lipid profile, BP and find the correlation of these parameters in the diabetic population of North Kerala.Methods: This was a cross sectional study among the type 2 diabetic patients with 40-60 years of age, and those without any cardiac, renal, liver, and thyroid dysfunction. Fasting blood sugar, BP, HbA1c and lipid profile were assessed by VITROS 5600 integrated system. The study population was grouped in to two based on their glycemic control (HbA1c ≥7% and HbA1c <7%). Statistical analysis was performed by SPSS software. The comparison of variables age, BP, FBS, HbA1c, total cholesterol, LDL, HDL, TG, and TG/HDL was tested using independent student t test. The correlations between the variables were analyzed using Pearson correlation coefficient. P values less than 0.05 were considered significant.Results: There was a significant positive correlation between DBP and poor glycemic control group (t=2.35, p=0.0102). Fasting blood sugar (p≤0.00001), total cholesterol (p=0.0031), triglycerides (p≤0.00001), LDL (p=0.0051), HDL (p=0.0010) and TG/HDL (p≤0.00001) also were significantly higher in this group. Age or gender showed no correlation with HbA1c and BP.Conclusions: This study shows highly significant positive correlation between TG/HDL and poor glycemic control. It appears the degree of hypertension is not correlated with HbA1c, but significantly correlated with lipid profile especially among those with poor glycemic control.

scholarly journals Role of eNOS and TGFβ1 gene polymorphisms in the development of diabetic nephropathy in type 2 diabetic patients in South Indian population

2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Sindhu Varghese ◽  
Subbaraj Gowtham Kumar
Keyword(s):  
Diabetic Nephropathy ◽  
Genetic Variants ◽  
Gene Polymorphisms ◽  
Indian Population ◽  
Diabetic Patients ◽  
South Indian Population ◽  
Type 2 Diabetic Patients ◽  
South Indian ◽  
Type 2 Diabetic

Abstract Background Diabetic nephropathy is known to be a leading complication of diabetes mellitus, characterized by diverse aspects such as high urinary albumin level, elevated blood pressure, and genetic susceptibility leading to end-stage renal disease. The current study was carried out to investigate the association of eNOS and TGFβ1 gene polymorphisms in the progression of diabetic nephropathy among type 2 diabetic patients in the South Indian population. The eNOS and TGFβ1 genetic variants were genotyped in 280 T2DM patients, 140 with DN, 140 without DN, and 140 controls. Genotyping was performed using ARMS PCR and the genomic variants were confirmed by the Sanger sequencing method. Results A significant (p < 0.05) association was observed in the genotypic frequencies of eNOS (G > T) polymorphism in the T2DM patients with diabetic nephropathy when compared to controls. The frequency of TT (heterozygous) genotype was observed to increase in patients with type 2 diabetes and DN when compared to the diabetic patients without DN and controls. This indicates that diabetic patients with TT genotype are at an increased risk to develop DN. However, TGFβ1 (G > C) polymorphism did not show any association in the allele and genotypic frequencies with DN when compared with T2DM and controls. Conclusion The results of the study propose a strong influence of TT genotype of eNOS gene be significantly linked with diabetic nephropathy in T2DM patients. Whereas no association was examined concerning TGFβ1 gene polymorphism and DN. Nevertheless, large sample size studies are required to confirm the part of these genetic variants in the development of DN.

scholarly journals Achievements of Diabetes Goals and Their Determinants in Type 2 Diabetic Patients Attending Outpatient Diabetic Clinic in Northern Ethiopia

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Ezra Belay ◽  
Abel Abera ◽  
Aman Mehari ◽  
Gidey Gebremeskel ◽  
Asrat Endrias ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glycemic Control ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Duration Of Diabetes ◽  
Type 2 Diabetic

Background. The aim of this study was to assess target diabetic goal achievements and to explore variables associated with them. Methods. A cross-sectional study was conducted between December 2015 and April 2016 on 188 type 2 diabetic patients attending Ayder Referral Hospital’s outpatient diabetic clinic. Glycemic control was assessed using fasting plasma glucose values and total cholesterol and triglyceride were used to evaluate lipid profiles. Bivariate and multivariate logistic regression analyses were done to identify factors associated with poor glycemic control, hypertension, and dyslipidemia. Result. Mean duration of diabetes was 6.5 years. Combined glycemic, lipid, and blood pressure targets were achieved only in 8.5% of the participants. More males achieved combined targets than females. Separately, while above two-thirds of the patients had poor glycemic control (67%), more than half of the participants have had poor lipid (58.5%) and blood pressure (52.1%) control. A significant portion of the patients (68.1%) had also comorbidities other than hyperglycemia. In bivariate and multivariate analyses, longer duration of diabetes disease (AOR: 3.4; P=0.013) and marked month to month fasting plasma glucose (FPG) variability as measured by large standard deviation (AOR: 2.5; P=0.023) were significantly associated with overall poor mean FPG results. Female sex was also significantly associated with dyslipidemia (AOR: 1.9; P=0.049). Conclusion. The study showed that achievements of combined diabetic goals are generally poor.

scholarly journals In vivo oxidizability of LDL in type 2 diabetic patients in good and poor glycemic control

2004 ◽  
Vol 173 (1) ◽  
pp. 103-107 ◽  
Author(s):  
R. Gambino ◽  
B. Uberti ◽  
N. Alemanno ◽  
E. Pisu ◽  
G. Pagano ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Poor Glycemic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic
Sign in / Sign up

Export Citation Format

Share Document