scholarly journals Study of biochemical parameters of atherosclerosis male patients in tertiary care hospital of Rewa, Madhya Pradesh, India

2018 ◽  
Vol 6 (7) ◽  
pp. 2401
Author(s):  
Drutpal Singh Baghel ◽  
Adesh Patidar
Keyword(s):  
Biochemical Parameters ◽  
Tertiary Care Hospital ◽  
Blood Clot ◽  
Tertiary Care ◽  
Western World ◽  
P Value ◽  
Care Hospital ◽  
Male Patients ◽  
Student’S T ◽  
A Prospective Study

Background: Atherosclerosis is characterized by intimal lesions called atheromas or atheromatous or fibro fatty plaques which protrude into and obstruct vascular lumens and weaken the underlying media. Global in distribution, atherosclerosis over whelming contributes to more mortality approximately half of all deaths and serious morbidity in the Western World than any other disorder. The atherosclerotic plaque is a lumpy thickening of the arterial wall, narrows the passage way and initiates the formation of a blood clot that can ultimately close down a critical artery. The objective of the study was to comparative biochemical parameters in different age group of atherosclerosis male patients.Methods: It was a prospective study, conducted in department of medicine of tertiary care hospital at Rewa. 30 atherosclerotic patients were selected for this study on the basis of inclusion and exclusion criteria, Biochemical testing was done for all patients and data of biochemical parameters were reported as the Mean±SD. Results were performed by the unpaired student’s t-test.Results: Total 30 atherosclerosis male patients and 27 normal healthy male volunteers were enrolled for the study. Biochemical parameters of both of this group were compared with t-test and p-value was found significant.Conclusions: Risk factors such as elevations in body mass index, systolic blood pressure, serum LDL cholesterol, triglyceride concentration and cigarette smoking are significantly related to the extent of atherosclerotic lesions.

Enhancing the empiric antibiotic selection by introducing an antibiogram toolkit in a tertiary care hospital in Southern India – A prospective study

2021 ◽  
Author(s):  
Sadagoban G. Krishnamoorthy ◽  
Vyshak Raj ◽  
Balasubramaniam Viswanathan ◽  
Ganga Priyadharshini Dhanasekaran ◽  
Dhivyaprasath Palaniappan ◽  
...  
Keyword(s):  
Prospective Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Southern India ◽  
Care Hospital ◽  
Antibiotic Selection ◽  
Empiric Antibiotic ◽  
A Prospective Study

scholarly journals ANALYSIS OF ADVERSE DRUG REACTIONS SPONTANEOUSLY REPORTED TO ADVERSE DRUG MONITORING CENTRE OF A TERTIARY CARE HOSPITAL–PROSPECTIVE STUDY

2018 ◽  
Vol 10 (1) ◽  
pp. 23
Author(s):  
Gajanan P. Kulkarni ◽  
Lokesh V. Patil
Keyword(s):  
Prospective Study ◽  
Adverse Drug Reactions ◽  
Causality Assessment ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Monitoring Centre ◽  
Organ Systems ◽  
A Prospective Study

Objective: To assess ADRs with reference to causative drugs, organ systems involved and seriousness of reactions.Methods: A prospective study conducted over a period of 1 y. The spontaneous adverse drug reactions reported between July 2016 and July 2017 at AMC centre BRIMS, Bidar were analyzed using Naranjo’s scale. Causality assessment of suspected drugs involved, system affected, and seriousness of reactions was assessed.Results: GIT system was most commonly involved, followed by generalized features, skin and appendages, CNS i. e, extrapyramidal system and dizziness, hearing and vestibular systems.Conclusion: Majority of the ADRs reported were mild to moderate severity and 20% can be categorized as severe reactions, which needed to treat under hospitalization

scholarly journals Assessment of adverse drug reaction profile of the disease-modifying anti-rheumatic drugs at the department of orthopaedics in a tertiary care hospital, Silchar, Assam, India

2019 ◽  
Vol 8 (5) ◽  
pp. 1007
Author(s):  
Vijoy S. Kairi ◽  
Pinaki Chakravarty ◽  
Arun Kumar Sipani
Keyword(s):  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Early Recognition ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Case Record ◽  
Medical College ◽  
Disease Modifying ◽  
Reaction Profile

Background: The mainstay of treatment of Rheumatoid Arthritis (RA) is the use of the disease-modifying anti-rheumatic drugs (DMARDs). Methotrexate, sulfasalazine and hydroxychloroquine are some of the DMARDs which are used in combination for the treatment of RA. The current study was undertaken to assess the adverse drug reactions (ADRs) of DMARDs that are commonly encountered with the treatment of RA.Methods: The present study was designed as a prospective, observational study on newly diagnosed patients with RA. Patients diagnosed with RA above 18 years (excluding pregnant women) of either sex who were prescribed DMARDs in combination were included. ADRs reported spontaneously by the patients and also responses obtained in a questionnaire related to likely ADRs from the patients was recorded in the case record form. Statistical analysis was done using graph pad and p value <0.05 was considered to be statistically significant.Results: A total of 47 patients attending the Outpatient Department of Orthopaedics, Silchar Medical College and Hospital, Silchar, Assam, India were screened for the study. ADRs were monitored up to the last visit on 41 patients excluding the patients who were lost and who were not able to adhere to the treatment. A total of 27 ADRs were reported from 19 ADR forms. Gastrointestinal manifestations were the most common adverse effects of combination DMARDs seen in 10 patients (24.39%). Severity assessment done using modified Hartwig and Siegel scale that showed majority of the ADRs were mild (74.07%).Conclusions: Present study showed that DMARDs are well-tolerated and have an acceptable toxicity profile as majority of ADRs seen were mild. It was however difficult to prevent the occurrence of ADRs. Proper monitoring of therapy is needed for early recognition of ADRs.

scholarly journals A Study of Acute Scrotum and its Management at a Tertiary Care Hospital: A Prospective Study

2019 ◽  
Vol 6 (42) ◽  
pp. 2765-2768
Author(s):  
Vamseedhar K. ◽  
Ramanaiah N. V. ◽  
Vasavya Umapathi K. ◽  
Vulchi Sree Rama Raju ◽  
Ganesh Reddy E. ◽  
...  
Keyword(s):  
Prospective Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Acute Scrotum ◽  
Care Hospital ◽  
A Prospective Study
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