scholarly journals Comparison of clinical profile of urban vs. rural Indian youth with premature coronary artery disease (PCAD): a sub-study of the PCAD registry

2019 ◽  
Vol 7 (2) ◽  
pp. 503
Author(s):  
Rahul Patil ◽  
Raghu T. R. ◽  
Manjunath C. N. ◽  
Vikrant Vijan ◽  
Santu Ghosh
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Profile ◽  
Rural Populations ◽  
Premature Coronary Artery Disease ◽  
Cross Sectional ◽  
Multi Centre Study ◽  
Artery Disease ◽  
Two Populations

Background: We aimed to compare clinical profile of premature coronary artery disease (PCAD) in urban vs. rural Indian populations.Methods: This was a prospective cross-sectional observational multi-centre study. This study is a sub-study of the ongoing PCAD registry. Between the period April 2017 and April 2018, a total of 1061 patients <40 years with PCAD were studied. Urban (n=583) and rural (n=478) populations were statistically compared.Results: Mean age of the urban and rural populations were 34.50±4.15 years and 33.99±4.46 years, respectively. All cardiovascular risk factors (smoking, diabetes, hypertension, dyslipidemia, obesity, diet and family history), except for alcoholism were more prevalent in urban subjects compared to rural subjects. However, higher prevalence of only hypertension (p=0.05) was statistically significant. Religion was significant between the two populations (p<0.001). Window period was also significant between the two populations (p<0.001). Very low density lipoprotein cholesterol (VLDL) (p=0.037) was significantly different between both populations.Conclusions: All conventional risk factors were more prevalent among urban populations than rural populations, however none of these differences except for hypertension was statistically significant.

Coronary risk factors in children of parents with premature coronary artery disease

1993 ◽  
Vol 82 (2) ◽  
pp. 162-165 ◽  
Author(s):  
Y Beigel ◽  
J George ◽  
L Leibovici ◽  
A Mattityahu ◽  
S Sclarovsky ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Premature Coronary Artery Disease ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Artery Disease

Study on Clinical Profile and risk factors of Coronary Artery Disease in Indian Women

2018 ◽  
Vol 4 (2) ◽  
pp. 94-99
Author(s):  
Keshavamurthy Ganapathy Bhat ◽  
◽  
Krishnakumar Kanniyyappan ◽  
Bhupinder Kaur Anand ◽  
Marwaha Manvinder Pal Singh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Profile ◽  
Indian Women ◽  
Artery Disease

scholarly journals Diabetes mellitus and other cardiovascular risk factors in lower-extremity peripheral artery disease versus coronary artery disease: an analysis of 1,121,359 cases from the nationwide databases

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Mitsuyoshi Takahara ◽  
◽  
Osamu Iida ◽  
Shun Kohsaka ◽  
Yoshimitsu Soga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Cardiovascular Risk Factors ◽  
Clinical Profile ◽  
Peripheral Artery ◽  
Artery Disease

Abstract Background Lower-extremity peripheral artery disease (LE-PAD) and coronary artery disease (CAD) are both pathologically rooted in atherosclerosis, and their shared clinical features regarding the exposure to cardiovascular risk factors have been emphasized. However, comparative data of the two cardiovascular diseases (CVDs) were so far lacking. The purpose of this study was to directly compare the clinical profile between cases undergoing endovascular therapy (EVT) for LE-PAD and those undergoing percutaneous coronary intervention (PCI). Methods Data were extracted from the nationwide procedural databases of EVT and PCI in Japan (J-EVT and J-PCI) between 2012 and 2017. A total of 1,121,359 cases (103,887 EVT cases for critical limb ischemia [CLI] or intermittent claudication and 1,017,472 PCI cases for acute coronary syndrome [ACS] or stable angina) were analyzed. Heterogeneity in clinical profile between CVDs was evaluated using the C statistic of the logistic regression model for which dependent variable was one CVD versus another, and explanatory variables were clinical profile. When two CVDs were completely discriminated from each other by the developed model, the C statistic (discrimination ability) of the model would be equal to 1, indicating that the two CVDs were completely different in clinical profile. On the other hand, when two CVDs were identical in clinical profile, the developed model would not discriminate them at all, with the C statistic equal to 0.5. Results Mean age was 73.5 ± 9.3 years in LE-PAD patients versus 70.0 ± 11.2 years in CAD patients (P < 0.001). The prevalence of diabetes mellitus and end-stage renal disease was 1.96- and 6.39-times higher in LE-PAD patients than in CAD patients (both P < 0.001). The higher prevalence was observed irrespective of age group. The exposure to other cardiovascular risk factors and the likelihood of cardiovascular risk clustering also varied between the diseases. The between-disease heterogeneity in patient profile was particularly evident between CLI and ACS, with the C statistic equal to 0.833 (95% CI 0.831–0.836). Conclusions The current study, an analysis based on nationwide procedural databases, confirmed that patient profiles were not identical but rather considerably different between clinically significant LE-PAD and CAD warranting revascularization.

scholarly journals Risk factors of premature coronary artery disease in Iran: A systematic review and meta‐analysis

2019 ◽  
Vol 49 (7) ◽  
Author(s):  
Hoorak Poorzand ◽  
Konstantinos Tsarouhas ◽  
Seyyed Amin Hozhabrossadati ◽  
Nastaran Khorrampazhouh ◽  
Yones Bondarsahebi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Meta Analysis ◽  
Premature Coronary Artery Disease ◽  
Artery Disease

scholarly journals Genetic Variants and Haplotypes in OPG Gene Are Associated with Premature Coronary Artery Disease and Traditional Cardiovascular Risk Factors in Mexican Population: The GEA Study

2020 ◽  
Vol 39 (11) ◽  
pp. 2085-2094
Author(s):  
Nonanzit Pérez-Hernández ◽  
Rosalinda Posadas-Sánchez ◽  
Gilberto Vargas-Alarcón ◽  
Benny Giovanni Cazarín-Santos ◽  
Antonio Miranda-Duarte ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Genetic Variants ◽  
Mexican Population ◽  
Premature Coronary Artery Disease ◽  
Artery Disease
Sign in / Sign up

Export Citation Format

Share Document